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In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

For the in vivo range verification in proton therapy, it has been tried to measure the spatial distribution of the prompt gammas generated by the proton-induced interactions with the close relationship with the proton dose distribution.…

医学物理 · 物理学 2015-03-13 Wook-Geun Shin , Chul Hee Min , Jae-Ik Shin , Jong Hwi Jeong , Se Byeong Lee

GASTOF (Gas Time-of-Flight) detector is a Cherenkov detector proposed for very precise (10--20 ps) arrival time measurements of forward protons at some 420 m from the central detectors of CMS and ATLAS. Such an excellent time resolution…

高能物理 - 唯象学 · 物理学 2008-11-26 L. Bonnet , T. Pierzchala , K. Piotrzkowski , P. Rodeghiero

Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose.…

Time-of-Flight (ToF) cameras possess compact design and high measurement precision to be applied to various robot tasks. However, their limited sensing range restricts deployment in large-scale scenarios. Depth completion has emerged as a…

机器人学 · 计算机科学 2026-03-24 Juncheng Chen , Tiancheng Lai , Xingpeng Wang , Bingxin Liao , Baozhe Zhang , Chao Xu , Yanjun Cao

We demonstrate the implementation of a simple time-of-flight (ToF) mass spectrometer with medium-mass resolution ($m/\Delta m\sim50$) geared towards the demands of atomic, molecular, and chemical physics experiments. By utilizing a novel…

We present a novel single-shot interferometric ToF camera targeted for precise 3D measurements of dynamic objects. The camera concept is based on Synthetic Wavelength Interferometry, a technique that allows retrieval of depth maps of…

计算机视觉与模式识别 · 计算机科学 2022-12-05 Manuel Ballester , Heming Wang , Jiren Li , Oliver Cossairt , Florian Willomitzer

Plastic scintillation detectors for Time-of-Flight (TOF) measurements are almost essential for event-by-event identification of relativistic rare isotopes. In this work, a pair of plastic scintillation detectors of 50 $\times$ 50 $\times$…

State-of-the-art time-of-flight (ToF) based 3D sensors suffer from poor lateral and depth resolutions. In this work, we introduce a novel sensor concept that provides ToF-based 3D measurements of real world objects with depth precisions up…

Ion computed tomography (iCT) is an imaging modality for the direct determination of the relative stopping power (RSP) distribution within a patient's body. Usually, this is done by estimating the path and energy loss of ions traversing the…

Proton computed tomography (CT) is similar to x-ray CT but relies on protons rather than photons to form an image. In its most common operation mode, the measured quantity is the amount of energy that a proton has lost while traversing the…

医学物理 · 物理学 2022-08-17 Nils Krah , Denis Dauvergne , Jean Michel Létang , Simon Rit , Étienne Testa

The photoneutron source (PNS, phase 1), an electron linear accelerator (linac)-based pulsed neutron facility that uses the time-of-flight (TOF) technique, was constructed for the acquisition of nuclear data from the thorium molten salt…

Hadrontherapy is a novel technique of cancer radiation therapy which employs beams of charged hadrons, protons and carbon ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal…

医学物理 · 物理学 2015-05-14 Saverio Braccini

Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…

仪器与探测器 · 物理学 2021-11-16 J. S. L. Yap , N. J. S. Bal , A. Kacperek , J. Resta López , C. P. Welsch

We present a novel method to correct flying pixels within data captured by Time-of-flight (ToF) sensors. Flying pixel (FP) artifacts occur when signals from foreground and background objects reach the same sensor pixel, leading to a…

图像与视频处理 · 电气工程与系统科学 2024-10-11 Ekamresh Vasudevan , Shashank N. Sridhara , Eduardo Pavez , Antonio Ortega , Raghavendra Singh , Srinath Kalluri

Measurement of the Time-of-Flight (TOF) of the 511 keV gammas brings an important reduction of statistical noise in the PET image, with higher precision time measurements producing clearer images. Scintillating crystals are used to convert…

仪器与探测器 · 物理学 2019-12-03 K. Doroud , Z. Liu , M. C. S. Williams

We report on an hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA…

Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…

Cone beam computed tomography (CBCT) for breast imaging has potential to replace conventional mammograms. However, concerns over dose and image quality prevent CBBCT systems from the clinical trial phase to next stage. The time of flight…

医学物理 · 物理学 2021-02-01 Ignacio O. Romero , Changqing Li

The distribution of the prompt gamma emissions induced by proton interactions in a target material carries information concerning the proton range and target composition. In order to image prompt gamma we present different approaches. The…