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相关论文: Sepsis World Model: A MIMIC-based OpenAI Gym "Worl…

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Sepsis management in the ICU requires sequential treatment decisions under rapidly evolving patient physiology. Although large language models (LLMs) encode broad clinical knowledge and can reason over guidelines, they are not inherently…

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

机器学习 · 计算机科学 2025-11-11 Atharva Thakur , Shruti Dhumal

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

机器学习 · 计算机科学 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst…

机器学习 · 计算机科学 2019-08-14 Supreeth P. Shashikumar , Christopher Josef , Ashish Sharma , Shamim Nemati

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

机器学习 · 计算机科学 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Sepsis is a lethal syndrome of organ dysfunction that is triggered by an infection and claims 11 million lives per year globally. Prognostic algorithms based on deep learning have shown promise in detecting the onset of sepsis hours before…

组织与器官 · 定量生物学 2024-08-19 Marco Giordano , Kanika Dheman , Michele Magno

Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection…

Sepsis is a dangerous condition that is a leading cause of patient mortality. Treating sepsis is highly challenging, because individual patients respond very differently to medical interventions and there is no universally agreed-upon…

机器学习 · 计算机科学 2018-11-28 Aniruddh Raghu , Matthieu Komorowski , Sumeetpal Singh

Sepsis is a condition caused by the body's overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure, and finally death. Common signs and symptoms include fever, increased heart rate, increased…

机器学习 · 计算机科学 2017-09-07 Eitam Sheetrit , Nir Nissim , Denis Klimov , Lior Fuchs , Yuval Elovici , Yuval Shahar

Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…

机器学习 · 计算机科学 2017-05-24 Aniruddh Raghu , Matthieu Komorowski , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Sepsis is a life-threatening condition affecting one million people per year in the US in which dysregulation of the body's own immune system causes damage to its tissues, resulting in a 28 - 50% mortality rate. Clinical trials for sepsis…

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

机器学习 · 计算机科学 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

These two synthetic datasets comprise vital signs, laboratory test results, administered fluid boluses and vasopressors for 3,910 patients with acute hypotension and for 2,164 patients with sepsis in the Intensive Care Unit (ICU). The…

机器学习 · 计算机科学 2021-12-09 Nicholas I-Hsien Kuo , Mark Polizzotto , Simon Finfer , Louisa Jorm , Sebastiano Barbieri

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

机器学习 · 计算机科学 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

Sepsis is one of the leading causes of death in Intensive Care Units (ICU). The strategy for treating sepsis involves the infusion of intravenous (IV) fluids and administration of antibiotics. Determining the optimal quantity of IV fluids…

人工智能 · 计算机科学 2020-09-18 Akash Gupta , Michael T. Lash , Senthil K. Nachimuthu

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

机器学习 · 计算机科学 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this…

Sepsis is a syndrome that develops in the body in response to the presence of an infection. Characterized by severe organ dysfunction, sepsis is one of the leading causes of mortality in Intensive Care Units (ICUs) worldwide. These…

机器学习 · 计算机科学 2023-11-20 Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

机器学习 · 计算机科学 2021-05-12 Margherita Rosnati , Vincent Fortuin
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