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The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…

定量方法 · 定量生物学 2026-02-17 Reza Bozorgpour , Jacob R. Rammer

The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…

计算工程、金融与科学 · 计算机科学 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Enrico Dall'Ara , Marco Viceconti

3D printing technology offers the possibility of producing synthetic samples with accurately defined microstructures. As indicated by effective medium theory (EMT), the shapes, orientations, and sizes of voids significantly affect the…

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

组织与器官 · 定量生物学 2023-03-24 Jennifer Buoncore , Alexis Sobecki , Brian Lee Beatty

The interaction between turbulence and surface tension is studied numerically using the one-dimensional-turbulence (ODT) model. ODT is a stochastic model simulating turbulent flow evolution along a notional one-dimensional line of sight by…

流体动力学 · 物理学 2024-04-16 A. Movaghar , R. Chiodi , M. Oevermann , O. Desjardins , A. R. Kerstein

The biomechanical properties of blood clots, which are dictated by their compositions and micro-structures, play a critical role in determining their fates, occlusion, persistency, or embolization in the human circulatory system. While…

生物物理 · 物理学 2024-03-18 Nicholas Filla , Beikang Gu , Jixin Hou , Kenan Song , He Li , Ning Liu , Xianqiao Wang

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

流体动力学 · 物理学 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

While stress visualization within 3-dimensional particles would greatly advance our understanding of the behaviors of complex particles, traditional photoelastic methods suffer from a lack of available technology for producing suitable…

The mechanisms of flow in suspensions of soft particles above the glass-transition volume fraction and in the jammed state were probed using Orthogonal Superposition Rheometry (OSR). A small amplitude oscillatory shear flow is superimposed…

软凝聚态物质 · 物理学 2026-02-06 Panagiota Bogri , Gabriele Pagani , Jan Vermant , Joris Sprakel , George Petekidis

Optical Coherence Tomography Angiography (OCTA) has been increasingly used in the management of eye and systemic diseases in recent years. Manual or automatic analysis of blood vessel in 2D OCTA images (en face angiograms) is commonly used…

图像与视频处理 · 电气工程与系统科学 2021-03-01 Shuai Yu , Jianyang Xie , Jinkui Hao , Yalin Zheng , Jiong Zhang , Yan Hu , Jiang Liu , Yitian Zhao

The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…

图像与视频处理 · 电气工程与系统科学 2023-11-10 Jiawen Li , Yunqian Huang , Sheng Song , Hongbo Chen , Junni Shi , Duo Xu , Haibin Zhang , Man Chen , Rui Zheng

Hemodynamic parameters are often estimated assuming a constant Newtonian viscosity, even though blood exhibits shear-thinning behavior. This article investigates the influence of blood rheology and hematocrit (Hct) percentage on the…

信号处理 · 电气工程与系统科学 2025-07-15 Hernán Mella , Felipe Galarce , Tetsuro Sekine , Julio Sotelo , Ernesto Castillo

Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…

图像与视频处理 · 电气工程与系统科学 2022-06-10 Ziyi Huang , Yu Gan , Theresa Lye , Yanchen Liu , Haofeng Zhang , Andrew Laine , Elsa Angelini , Christine Hendon

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

流体动力学 · 物理学 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

Segmentation of blood vessels in murine cerebral 3D OCTA images is foundational for in vivo quantitative analysis of the effects of neurovascular disorders, such as stroke or Alzheimer's, on the vascular network. However, to accurately…

图像与视频处理 · 电气工程与系统科学 2024-03-13 Bastian Wittmann , Lukas Glandorf , Johannes C. Paetzold , Tamaz Amiranashvili , Thomas Wälchli , Daniel Razansky , Bjoern Menze

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

流体动力学 · 物理学 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

Typical approaches to patient-specific hemodynamic studies of cerebral aneurysms use image based computational fluid dynamics (CFD) and seek to statistically correlate parameters such as wall shear stress (WSS) and oscillatory shear index…

Shear stresses are the driving forces for the creation of both point and extended defects in crystals subjected to high pressures and temperatures. Recently, we observed anomalous elastic materials response in shock-compressed silicon and…

材料科学 · 物理学 2009-11-11 I. I. Oleynik , S. V. Zybin , M. L. Elert , C. T. White