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Pain in sickle cell disease (SCD) is often associated with increased morbidity, mortality, and high healthcare costs. The standard method for predicting the absence, presence, and intensity of pain has long been self-report. However,…

计算机与社会 · 计算机科学 2025-11-21 Swati Padhee , Amanuel Alambo , Tanvi Banerjee , Arvind Subramaniam , Daniel M. Abrams , Gary K. Nave , Nirmish Shah

Recently, computer-aided diagnostic systems (CADs) that could automatically interpret medical images effectively have been the emerging subject of recent academic attention. For radiographs, several deep learning-based systems or models…

计算机视觉与模式识别 · 计算机科学 2020-09-15 Hieu X. Le , Phuong D. Nguyen , Thang H. Nguyen , Khanh N. Q. Le , Thanh T. Nguyen

The level of PD-L1 expression in immunohistochemistry (IHC) assays is a key biomarker for the identification of Non-Small-Cell-Lung-Cancer (NSCLC) patients that may respond to anti PD-1/PD-L1 treatments. The quantification of PD-L1…

计算机视觉与模式识别 · 计算机科学 2018-12-03 Ansh Kapil , Armin Meier , Aleksandra Zuraw , Keith Steele , Marlon Rebelatto , Günter Schmidt , Nicolas Brieu

With the increasing use of smartphones in our daily lives, these devices have become capable of performing many complex tasks. Concerning the need for continuous monitoring of vital signs, especially for the elderly or those with certain…

信号处理 · 电气工程与系统科学 2024-03-29 Taha Samavati , Mahdi Farvardin , Aboozar Ghaffari

The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have…

图像与视频处理 · 电气工程与系统科学 2025-02-03 Gergely Szabó , Paolo Bonaiuti , Andrea Ciliberto , András Horváth

Understanding sickle cell dynamics requires accurate identification of morphological transitions under diverse biophysical conditions, particularly in densely packed and overlapping cell populations. Here, we present an automated deep…

计算机视觉与模式识别 · 计算机科学 2026-02-06 Nikhil Kadivar , Guansheng Li , Jianlu Zheng , Ming Dao , George Em Karniadakis , Mengjia Xu

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

Physical photographs now can be conveniently scanned by smartphones and stored forever as a digital version, yet the scanned photos are not restored well. One solution is to train a supervised deep neural network on many digital photos and…

计算机视觉与模式识别 · 计算机科学 2021-08-19 Man M. Ho , Jinjia Zhou

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

定量方法 · 定量生物学 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

图像与视频处理 · 电气工程与系统科学 2020-04-06 Filip Lux , Petr Matula

The outbreak of COVID-19 exposed the inadequacy of our technical tools for home health surveillance, and recent studies have shown the potential of smartphones as a universal optical microscopic imaging platform for such applications.…

图像与视频处理 · 电气工程与系统科学 2023-12-20 Haoran Zhang , Weiyi Zhang , Zirui Zuo , Jianlong Yang

Results: We present an application that enables the quantitative analysis of multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels,…

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

图像与视频处理 · 电气工程与系统科学 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

图像与视频处理 · 电气工程与系统科学 2024-01-08 Manoj S H , Arya A Bosale

Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…

图像与视频处理 · 电气工程与系统科学 2020-11-22 Hina Raja , Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Accelerating material discovery has tremendous societal and industrial impact, particularly for pharmaceuticals and clean energy production. Many experimental instruments have some degree of automation, facilitating continuous running and…

计算机视觉与模式识别 · 计算机科学 2022-03-22 Gabriella Pizzuto , Jacopo de Berardinis , Louis Longley , Hatem Fakhruldeen , Andrew I. Cooper

This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single…

计算机与社会 · 计算机科学 2019-01-07 Neil Deshmukh

This paper proposes a novel automatic classification framework for the recognition of five types of white blood cells. Segmenting complete white blood cells from blood smears images and extracting advantageous features from them remain…

计算机视觉与模式识别 · 计算机科学 2020-09-07 Na Dong , Meng-die Zhai , Jian-fang Chang , Chun-ho Wu