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Brain-Computer Interfaces enable direct communication between the brain and external systems, with functional Near-Infrared Spectroscopy emerging as a portable and non-invasive method for capturing cerebral hemodynamics. This study…

神经元与认知 · 定量生物学 2025-05-16 Mohammad Ghalavand , Javad Hatami , Seyed Kamaledin Setarehdan , Hananeh Ghalavand

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

神经元与认知 · 定量生物学 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

A mixed suspension of red blood cells (RBCs) and microparticles flows through a cylindrical channel with a constriction mimicking a stenosed blood vessel. Our three-dimensional Lattice-Boltzmann simulations show that the RBCs are depleted…

流体动力学 · 物理学 2017-02-01 Christian Bächer , Lukas Schrack , Stephan Gekle

To characterize atypical brain dynamics under diseases, prevalent studies investigate functional magnetic resonance imaging (fMRI). However, most of the existing analyses compress rich spatial-temporal information as the brain functional…

图像与视频处理 · 电气工程与系统科学 2023-05-08 Xiaozhao Liu , Mianxin Liu , Lang Mei , Yuyao Zhang , Feng Shi , Han Zhang , Dinggang Shen

Heterogeneous treatment effect estimation is an important problem in precision medicine. Specific interests lie in identifying the differential effect of different treatments based on some external covariates. We propose a novel…

统计方法学 · 统计学 2024-10-21 Peter Chang , Arkaprava Roy

Modern nonlinear control theory seeks to develop feedback controllers that endow systems with properties such as safety and stability. The guarantees ensured by these controllers often rely on accurate estimates of the system state for…

系统与控制 · 电气工程与系统科学 2020-11-02 Sarah Dean , Andrew J. Taylor , Ryan K. Cosner , Benjamin Recht , Aaron D. Ames

Mediation analysis aims to decipher the underlying causal mechanisms between an exposure, an outcome, and intermediate variables called mediators. Initially developed for fixed-time mediator and outcome, it has been extended to the…

统计方法学 · 统计学 2025-01-15 K. Le Bourdonnec , L. Valeri , C. Proust-Lima

A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It is hypothesized that a microstate implements a functional/physiological state of the brain during…

It is shown that the dependence of the cerebral blood flow (CBF) on mean arterial blood pressure (MABP) can be described with a simple model having the following assumptions. Below certain MABP (denoted as MABP1) there are no autoregulatory…

生物物理 · 物理学 2011-03-30 Alexander Gersten

Adequate brain perfusion is required for proper brain function and life. Maintaining optimal brain perfusion to avoid secondary brain injury is one of the main concerns of neurocritical care. Cerebral autoregulation is responsible for…

定量方法 · 定量生物学 2022-02-09 J. K. Briggs , J. N. Stroh , T. D. Bennett , S. Park , D. J. Albers

Among the major factors controlling the cerebral blood flow (CBF) - cerebral perfusion pressure, arterial partial pressure of oxygen (PaO2), cerebral metabolism, arterial partial pressure of carbon dioxide (PaCO2), and cardiac output, the…

医学物理 · 物理学 2007-05-23 A. Gersten

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

机器学习 · 计算机科学 2024-12-02 Guiran Liu , Binrong Zhu

Baroreflex (BR) and cerebral autoregulation (CA) are two important mechanisms regulating blood pressure and flow. However, the functional relationship between BR and CA in humans is unknown. Since BR impairment is an adverse prognostic…

组织与器官 · 定量生物学 2015-12-16 Adam Mahdi , Mette S. Olufsen , Stephen J. Payne

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

统计理论 · 数学 2008-08-08 Chunming Zhang , Tao Yu

We present a data-driven framework to characterize large-scale brain dynamical states directly from correlation matrices at the single-subject level. By treating correlation thresholding as a percolation-like probe of connectivity, the…

Motor imagery based brain-computer interfaces (MI-BCIs) allow the control of devices and communication by imagining different muscle movements. However, most studies have reported a problem of "BCI-illiteracy" that does not have enough…

神经元与认知 · 定量生物学 2020-02-21 Jae-Geun Yoon , Minji Lee

A brain--machine interface (BMI) based on motor imagery (MI) enables the control of devices using brain signals while the subject imagines performing a movement. It plays a vital role in prosthesis control and motor rehabilitation. To…

信号处理 · 电气工程与系统科学 2024-09-20 Xiaying Wang , Michael Hersche , Michele Magno , Luca Benini

A BEC interacting with an optical field via a feedback mirror can be a realisation of the quantum Hamiltonian Mean Field (HMF) model, a paradigmatic model of long-range interactions in quantum systems. We demonstrate that the…

量子物理 · 物理学 2023-07-12 Gordon Robb , Josh Walker , Gian-Luca Oppo , Thorsten Ackemann

Now over 20 years old, functional MRI (fMRI) has a large and growing literature that is best synthesised with meta-analytic tools. As most authors do not share image data, only the peak activation coordinates (foci) reported in the paper…

统计方法学 · 统计学 2016-06-23 Silvia Montagna , Tor Wager , Lisa Feldman-Barrett , Timothy D. Johnson , Thomas E. Nichols

Being able to adequately process and combine data arising from different sites is crucial in neuroimaging, but is difficult, owing to site, sequence and acquisition-parameter dependent biases. It is important therefore to design algorithms…

图像与视频处理 · 电气工程与系统科学 2021-11-05 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso