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Electronic Health Records (EHRs) exhibit a high amount of missing data due to variations of patient conditions and treatment needs. Imputation of missing values has been considered an effective approach to deal with this challenge. Existing…

机器学习 · 计算机科学 2022-10-25 Yuxi Liu , Shaowen Qin , Zhenhao Zhang , Wei Shao

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

This work presents a novel semi-supervised learning approach for data-driven modeling of asset failures when health status is only partially known in historical data. We combine a generative model parameterized by deep neural networks with…

机器学习 · 计算机科学 2017-09-05 Andre S. Yoon , Taehoon Lee , Yongsub Lim , Deokwoo Jung , Philgyun Kang , Dongwon Kim , Keuntae Park , Yongjin Choi

Medical vision-language datasets are often limited in size and biased toward negative findings, as clinicians report abnormalities mostly but might omit some positive/neutral findings because they might be considered as irrelevant to the…

机器学习 · 计算机科学 2026-04-14 Halil Ibrahim Gulluk , Olivier Gevaert

Structural failure time models are causal models for estimating the effect of time-varying treatments on a survival outcome. G-estimation and artificial censoring have been proposed to estimate the model parameters in the presence of…

统计方法学 · 统计学 2019-02-19 Shu Yang , Karen Pieper , Frank Cools

Conventional approaches to statistical inference preclude structures that facilitate incorporation of supplemental information acquired from similar circumstances. For example, the analysis of data obtained using perfusion computed…

应用统计 · 统计学 2015-11-18 Thomas A. Murray , Brian P. Hobbs , Bradley P. Carlin

Estimating the cure fraction in a diseased population, especially in the presence of competing mortality causes, is crucial for both patients and clinicians. It offers a valuable measure for monitoring and interpreting trends in disease…

统计方法学 · 统计学 2025-04-08 Fabrizio Di Mari , Roberto Rocci , Silvia Rossi , Giovanna Tagliabue , Roberta De Angelis

Electronic medical records (EMRs) supports the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But insofar most algorithms have been centralized,…

机器学习 · 计算机科学 2019-03-25 Li Huang , Dianbo Liu

We propose a new method of classifying documents into categories. The simple method of conducting hypothesis testing over word-based distributions in categories suffers from the data sparseness problem. In order to address this difficulty,…

cmp-lg · 计算机科学 2008-02-03 Hang Li , Kenji Yamanishi

In this paper, we extend the vertical modeling approach for the analysis of survival data with competing risks to incorporate a cured fraction in the population, that is, a proportion of the population for which none of the competing events…

统计方法学 · 统计学 2015-08-18 M. A. Nicolaie , J. M. G. Taylor , C. Legrand

Structural health monitoring (SHM) relies on non-destructive techniques such as acoustic emission (AE) that generate large amounts of data over the lifespan of systems. Clustering methods are used to interpret these data and gain insights…

We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

机器学习 · 计算机科学 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

Traditional statistical inference in cluster randomized trials typically invokes the asymptotic theory that requires the number of clusters to approach infinity. In this article, we propose an alternative conformal causal inference…

统计方法学 · 统计学 2024-10-03 Bingkai Wang , Fan Li , Mengxin Yu

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Measurement error arises commonly in clinical research settings that rely on data from electronic health records or large observational cohorts. In particular, self-reported outcomes are typical in cohort studies for chronic diseases such…

统计方法学 · 统计学 2021-02-08 Lillian A. Boe , Lesley F. Tinker , Pamela A. Shaw

We consider survival data in the presence of a cure fraction, meaning that some subjects will never experience the event of interest. We assume a mixture cure model consisting of two sub-models: one for the probability of being uncured…

统计方法学 · 统计学 2023-03-17 Eni Musta , Tsz Pang Yuen

In the context of clinical and biomedical studies, joint frailty models have been developed to study the joint temporal evolution of recurrent and terminal events, capturing both the heterogeneous susceptibility to experiencing a new…

统计方法学 · 统计学 2023-11-08 Chiara Masci , Marta Spreafico , Francesca Ieva

In this paper, we consider the task of clustering a set of individual time series while modeling each cluster, that is, model-based time series clustering. The task requires a parametric model with sufficient flexibility to describe the…

机器学习 · 计算机科学 2023-02-23 Ryohei Umatani , Takashi Imai , Kaoru Kawamoto , Shutaro Kunimasa

In this article, we propose a penalized clustering method for large scale data with multiple covariates through a functional data approach. In the proposed method, responses and covariates are linked together through nonparametric…

统计方法学 · 统计学 2008-01-17 Ping Ma , Wenxuan Zhong