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相关论文: Challenges for automated spike sorting: beware of …

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Reliable spike detection and sorting, the process of assigning each detected spike to its originating neuron, is an essential step in the analysis of extracellular electrical recordings from neurons. The volume and complexity of the data…

神经元与认知 · 定量生物学 2018-09-05 Matthias H. Hennig , Cole Hurwitz , Martino Sorbaro

Spikes in the membrane electrical potentials of neurons play a major role in the functioning of nervous systems of animals. Obtaining the spikes from different neurons has been a challenging problem for decades. Several schemes have been…

定量方法 · 定量生物学 2016-02-11 Anupam Mitra , Anagh Pathak , Kaushik Majumdar

Extracellular recordings with multi-electrode arrays is one of the basic tools of contemporary neuroscience. These recordings are mostly used to monitor the activities, understood as sequences of emitted action potentials, of many…

计算工程、金融与科学 · 计算机科学 2014-12-22 Christophe Pouzat , Georgios Is. Detorakis

Spike sorting refers to the problem of assigning action potentials observed in extra-cellular recordings of neural activity to the neuron(s) from which they originate. We cast this problem as one of learning a convolutional dictionary from…

统计方法学 · 统计学 2018-06-07 Andrew H. Song , Francisco Flores , Demba Ba

This paper deals with the problem of extracting the activity of individual neurons from multi-electrode recordings. Important aspects of this work are: 1) the sorting is done in two stages - a statistical model of the spikes from different…

数据分析、统计与概率 · 物理学 2007-05-23 Dima Rinberg , William Bialek , Hanan Davidowitz , Naftali Tishby

One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

神经元与认知 · 定量生物学 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

We introduce a new supervised learning algorithm based to train spiking neural networks for classification. The algorithm overcomes a limitation of existing multi-spike learning methods: it solves the problem of interference between…

神经与进化计算 · 计算机科学 2021-08-12 Huy Le Nguyen , Dominique Chu

Understanding the function of complex cortical circuits requires the simultaneous recording of action potentials from many neurons in awake and behaving animals. Practically, this can be achieved by extracellularly recording from multiple…

定量方法 · 定量生物学 2008-09-25 Ueli Rutishauser , Erin M. Schuman , Adam N. Mamelak

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

机器学习 · 计算机科学 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

An important prerequisite for the analysis of spike synchrony in extracellular recordings is the extraction of single unit activity from the recorded multi unit signal. To identify single units (SUs), potential spikes are detected and…

神经元与认知 · 定量生物学 2018-11-01 Jeyathevy Sukiban , Nicole Voges , Till A. Dembek , Robin Pauli , Michael Denker , Immo Weber , Lars Timmermann , Sonja Grün

Decoding extracellular recordings is a crucial task in electrophysiology and brain-computer interfaces. Spike sorting, which distinguishes spikes and their putative neurons from extracellular recordings, becomes computationally demanding…

信号处理 · 电气工程与系统科学 2024-12-31 Yuntao Han , Shiwei Wang

Estimating neuron location from extracellular recordings is essential for developing advanced brain-machine interfaces. Accurate neuron localization improves spike sorting, which involves detecting action potentials and assigning them to…

神经元与认知 · 定量生物学 2025-08-20 Hao Zhao , Xinhe Zhang , Arnau Marin-Llobet , Xinyi Lin , Jia Liu

Spike sorting is a fundamental preprocessing step in neuroscience that is central to access simultaneous but distinct neuronal activities and therefore to better understand the animal or even human brain. But numerical complexity limits…

机器学习 · 统计学 2019-07-01 Laurent Dragoni , Rémi Flamary , Karim Lounici , Patricia Reynaud-Bouret

Spike sorting is an essential process in neural recording, which identifies and separates electrical signals from individual neurons recorded by electrodes in the brain, enabling researchers to study how specific neurons communicate and…

神经元与认知 · 定量生物学 2025-12-23 Yimu Zhang , Dongqi Han , Yansen Wang , Zhenning Lv , Yu Gu , Dongsheng Li

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

神经与进化计算 · 计算机科学 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Two major initiatives to accelerate research in the brain sciences have focused attention on developing a new generation of scientific instruments for neuroscience. These instruments will be used to record static (structural) and dynamic…

Human brain neuron activities are incredibly significant nowadays. Neuronal behavior is assessed by analyzing signal data such as electroencephalography (EEG), which can offer scientists valuable information about diseases and…

Modern recording technologies now enable simultaneous recording from large numbers of neurons. This has driven the development of new statistical models for analyzing and interpreting neural population activity. Here we provide a broad…

神经元与认知 · 定量生物学 2021-07-13 Cole Hurwitz , Nina Kudryashova , Arno Onken , Matthias H. Hennig

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

神经与进化计算 · 计算机科学 2021-01-27 Christoph Stöckl , Wolfgang Maass

We propose a construction for joint feature learning and clustering of multichannel extracellular electrophysiological data across multiple recording periods for action potential detection and discrimination ("spike sorting"). Our…

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