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In rare disease physician targeting, a major challenge is how to identify physicians who are treating diagnosed or underdiagnosed rare diseases patients. Rare diseases have extremely low incidence rate. For a specified rare disease, only a…

机器学习 · 统计学 2017-01-23 Yong Cai , Yunlong Wang , Dong Dai

Unsupervised domain adaptation for object detection is a challenging problem with many real-world applications. Unfortunately, it has received much less attention than supervised object detection. Models that try to address this task tend…

计算机视觉与模式识别 · 计算机科学 2021-06-11 Hongsong Wang , Shengcai Liao , Ling Shao

Routinely collected clinical blood tests are an emerging molecular data source for large-scale biomedical research but inherently feature irregular sampling and informative observation. Traditional approaches rely on imputation, which can…

定量方法 · 定量生物学 2025-03-20 Andrea Zerio , Maya Bechler-Speicher , Tine Jess , Aleksejs Sazonovs

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

计算机视觉与模式识别 · 计算机科学 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

This paper proposes an innovative Attention-GAN framework for enhancing cybersecurity, focusing on anomaly detection. In response to the challenges posed by the constantly evolving nature of cyber threats, the proposed approach aims to…

密码学与安全 · 计算机科学 2024-02-29 Mohammed Abo Sen

Disease severity regression by a convolutional neural network (CNN) for medical images requires a sufficient number of image samples labeled with severity levels. Conditional generative adversarial network (cGAN)-based data augmentation…

图像与视频处理 · 电气工程与系统科学 2023-02-27 Shumpei Takezaki , Kiyohito Tanaka , Seiichi Uchida , Takeaki Kadota

Minimizing the need for pixel-level annotated data to train PET lesion detection and segmentation networks is highly desired and can be transformative, given time and cost constraints associated with expert annotations. Current unsupervised…

图像与视频处理 · 电气工程与系统科学 2025-09-18 Shadab Ahamed , Arman Rahmim

Generative adversarial networks (GANs) are able to model the complex highdimensional distributions of real-world data, which suggests they could be effective for anomaly detection. However, few works have explored the use of GANs for the…

机器学习 · 计算机科学 2019-05-03 Houssam Zenati , Chuan Sheng Foo , Bruno Lecouat , Gaurav Manek , Vijay Ramaseshan Chandrasekhar

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

图像与视频处理 · 电气工程与系统科学 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel

Medical image reconstruction is typically an ill-posed inverse problem. In order to address such ill-posed problems, the prior distribution of the sought after object property is usually incorporated by means of some sparsity-promoting…

图像与视频处理 · 电气工程与系统科学 2020-01-30 Sayantan Bhadra , Weimin Zhou , Mark A. Anastasio

Early detection of many life-threatening diseases (e.g., prostate and breast cancer) within at-risk population can improve clinical outcomes and reduce cost of care. While numerous disease-specific "screening" tests that are closer to…

For most diseases, building large databases of labeled genetic data is an expensive and time-demanding task. To address this, we introduce genetic Generative Adversarial Networks (gGAN), a semi-supervised approach based on an innovative GAN…

机器学习 · 计算机科学 2020-07-03 Caio Davi , Ulisses Braga-Neto

This paper introduces a paradigm of smartphone application based disease diagnostics that may completely revolutionise the way healthcare services are being provided. Although primarily aimed to assist the problems in rendering the…

图像与视频处理 · 电气工程与系统科学 2020-08-21 Hrithwik Shalu , Harikrishnan P , Akash Das , Megdut Mandal , Harshavardhan M Sali , Juned Kadiwala

Noisy data and the similarity in the ocular appearances caused by different ophthalmic pathologies pose significant challenges for an automated expert system to accurately detect retinal diseases. In addition, the lack of knowledge…

图像与视频处理 · 电气工程与系统科学 2021-10-20 Sharif Amit Kamran , Alireza Tavakkoli , Stewart Lee Zuckerbrod

Fine-grained recognition is challenging due to its subtle local inter-class differences versus large intra-class variations such as poses. A key to address this problem is to localize discriminative parts to extract pose-invariant features.…

计算机视觉与模式识别 · 计算机科学 2017-03-22 Xiao Liu , Tian Xia , Jiang Wang , Yi Yang , Feng Zhou , Yuanqing Lin

In this paper, we present a memory-augmented algorithm for anomaly detection. Classical anomaly detection algorithms focus on learning to model and generate normal data, but typically guarantees for detecting anomalous data are weak. The…

机器学习 · 计算机科学 2020-02-10 Ziyi Yang , Teng Zhang , Iman Soltani Bozchalooi , Eric Darve

Vessel segmentation is crucial in many medical image applications, such as detecting coronary stenoses, retinal vessel diseases and brain aneurysms. However, achieving high pixel-wise accuracy, complete topology structure and robustness to…

计算机视觉与模式识别 · 计算机科学 2023-05-11 Tianyi Shi , Xiaohuan Ding , Wei Zhou , Feng Pan , Zengqiang Yan , Xiang Bai , Xin Yang

Imbalanced regression arises when the target distribution is skewed, causing models to focus on dense regions and struggle with underrepresented (minority) samples. Despite its relevance across many applications, few methods have been…

机器学习 · 计算机科学 2025-08-05 Shayan Alahyari , Shiva Mehdipour Ghobadlou , Mike Domaratzki

Unsupervised anomaly detection (UAD) learns one-class classifiers exclusively with normal (i.e., healthy) images to detect any abnormal (i.e., unhealthy) samples that do not conform to the expected normal patterns. UAD has two main…

计算机视觉与模式识别 · 计算机科学 2021-07-01 Yu Tian , Guansong Pang , Fengbei Liu , Yuanhong chen , Seon Ho Shin , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro