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This paper explores Bayesian inference for a biased sampling model in situations where the population of interest cannot be sampled directly, but rather through an indirect and inherently biased method. Observations are viewed as being the…

应用统计 · 统计学 2007-11-26 Russell Zaretzki , Michael A. Gilchrist , William M. Briggs , Artin Armagan

We investigate a simple objective for nonlinear instrumental variable (IV) regression based on a kernelized conditional moment restriction (CMR) known as a maximum moment restriction (MMR). The MMR objective is formulated by maximizing the…

机器学习 · 计算机科学 2023-02-10 Rui Zhang , Masaaki Imaizumi , Bernhard Schölkopf , Krikamol Muandet

This paper develops a semiparametric Bayesian instrumental variable analysis method for estimating the causal effect of an endogenous variable when dealing with unobserved confounders and measurement errors with partly interval-censored…

统计方法学 · 统计学 2025-01-28 Elvis Han Cui , Xuyang Lu , Jin Zhou , Hua Zhou , Gang Li

Measurement error can often be harmful when estimating causal effects. Two scenarios in which this is the case are in the estimation of (a) the average treatment effect when confounders are measured with error and (b) the natural indirect…

统计方法学 · 统计学 2024-06-04 Caleb H. Miles , Linda Valeri , Brent Coull

In clinical trials, inferences on clinical outcomes are often made conditional on specific selective processes. For instance, only when a treatment demonstrates a significant effect on the primary outcome, further analysis is conducted to…

统计方法学 · 统计学 2025-04-15 Tianyu Pan , Vivek Charu , Ying Lu , Lu Tian

In this paper, we discuss causal inference on the efficacy of a treatment or medication on a time-to-event outcome with competing risks. Although the treatment group can be randomized, there can be confoundings between the compliance and…

统计方法学 · 统计学 2016-12-06 Cheng Zheng , Ran Dai , Parameswaran Hari , Mei-Jie Zhang

In the statistical literature, a number of methods have been proposed to ensure valid inference about marginal effects of variables on a longitudinal outcome in settings with irregular monitoring times. However, the potential biases due to…

统计方法学 · 统计学 2021-12-23 Janie Coulombe , Erica E M Moodie , Robert W Platt

In Mendelian randomization (MR) studies, genetic variants are used as instrumental variables (IVs) to investigate causal relationships between exposures and outcomes based on observational data. However, numerous genetic studies have shown…

统计方法学 · 统计学 2026-04-10 Julien St-Pierre , Archer Y. Yang , Mireille E. Schnitzer , Marc-André Legault

External controls from historical trials or observational data can augment randomized controlled trials when large-scale randomization is impractical or unethical, such as in drug evaluation for rare diseases. However, non-randomized…

统计方法学 · 统计学 2025-05-08 Ke Zhu , Shu Yang , Xiaofei Wang

The identification of pollutant effects is an important task in environmental health. Bayesian kernel machine regression (BKMR) is a standard tool for inference of individual-level pollutant health-effects, and we present a mean field…

统计计算 · 统计学 2018-11-08 Raphael Small , Brent A. Coull

Causal effect moderation investigates how the effect of interventions (or treatments) on outcome variables changes based on observed characteristics of individuals, known as potential effect moderators. With advances in data collection,…

统计方法学 · 统计学 2024-11-26 Soham Bakshi , Walter Dempsey , Snigdha Panigrahi

We present a randomization-based inferential framework for experiments characterized by a strongly ignorable assignment mechanism where units have independent probabilities of receiving treatment. Previous works on randomization tests often…

统计方法学 · 统计学 2019-02-01 Zach Branson , Marie-Abele Bind

Inference in models where the parameter is defined by moment inequalities is of interest in many areas of economics. This paper develops a new method for improving the performance of generalized moment selection (GMS) testing procedures in…

计量经济学 · 经济学 2020-08-26 Rami V. Tabri , Christopher D. Walker

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

Mendelian randomization is a powerful tool for inferring the presence, or otherwise, of causal effects from observational data. However, the nature of genetic variants is such that pleiotropy remains a barrier to valid causal effect…

统计方法学 · 统计学 2021-08-04 Andrew J. Grant , Stephen Burgess

Robins 1997 introduced marginal structural models (MSMs), a general class of counterfactual models for the joint effects of time-varying treatment regimes in complex longitudinal studies subject to time-varying confounding. In his work,…

统计方法学 · 统计学 2020-07-27 Haben Michael , Yifan Cui , Scott Lorch , Eric Tchetgen Tchetgen

Mendelian randomization (MR) is a powerful approach to examine the causal relationships between health risk factors and outcomes from observational studies. Due to the proliferation of genome-wide association studies (GWASs) and abundant…

统计方法学 · 统计学 2020-09-02 Qing Cheng , Baoluo Sun , Yingcun Xia , Jin Liu

The quantification and inference of predictive importance for exposure covariates have recently gained significant attention in the context of interpretable machine learning. Contemporary scientific investigations often involve data…

统计方法学 · 统计学 2024-12-31 Zitao Wang , Nian Si , Zijian Guo , Molei Liu

The recent availability of huge, many-dimensional data sets, like those arising from genome-wide association studies (GWAS), provides many opportunities for strengthening causal inference. One popular approach is to utilize these…

机器学习 · 统计学 2020-12-21 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

We develop randomization-based tests for heterogeneous treatment effects in the presence of network interference. Leveraging the exposure mapping framework, we study a broad class of null hypotheses that represent various forms of constant…

计量经济学 · 经济学 2025-06-25 Julius Owusu