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Nonparametric Instrumental Variables (NPIV) analysis is based on a conditional moment restriction. We show that if this moment condition is even slightly misspecified, say because instruments are not quite valid, then NPIV estimates can be…

计量经济学 · 经济学 2022-12-13 Ben Deaner

We extend Fisher's randomization test (FRT) to test conditional independence between observed outcomes and treatments given covariates in both randomized experiments and observational studies, with no restriction on the variable type of…

统计方法学 · 统计学 2025-06-12 Zhen Zhong

In all measurement campaigns, one needs to assert that the instrumentation tools do not significantly impact the system being monitored. This is critical to future claims based on the collected data and is sometimes overseen in experimental…

性能 · 计算机科学 2012-05-18 Olivier Mehani , Guillaume Jourjon , Thierry Rakotoarivelo

Exposure measurement error is a ubiquitous but often overlooked challenge in causal inference with observational data. Existing methods accounting for exposure measurement error largely rely on restrictive parametric assumptions, while…

统计方法学 · 统计学 2025-06-27 Keith Barnatchez , Rachel Nethery , Bryan E. Shepherd , Giovanni Parmigiani , Kevin P. Josey

Real-World Data (RWD), with its large sample sizes and rich clinical detail, offers a compelling alternative to randomized controlled trials (RCTs) for studying treatment effects in diverse and complex patient populations. However, its…

应用统计 · 统计学 2026-05-26 Yifei Xu , Hwiyoung Lee , Zhenyao Ye , Yezhi Pan , Jingsong Zhou , Yun Yang , Chixiang Chen , Shuo Chen

Recently, there has been a surge in methodological development for the difference-in-differences (DiD) approach to evaluate causal effects. Standard methods in the literature rely on the parallel trends assumption to identify the average…

统计方法学 · 统计学 2023-10-17 Pan Zhao , Yifan Cui

Causal inference is the process of using assumptions, study designs, and estimation strategies to draw conclusions about the causal relationships between variables based on data. This allows researchers to better understand the underlying…

机器学习 · 计算机科学 2022-12-13 Anpeng Wu , Kun Kuang , Ruoxuan Xiong , Fei Wu

The inferential models (IM) framework provides prior-free, frequency-calibrated, posterior probabilistic inference. The key is the use of random sets to predict unobservable auxiliary variables connected to the observable data and unknown…

统计理论 · 数学 2016-01-26 Ryan Martin , Chuanhai Liu

Randomization tests are a popular method for testing causal effects in clinical trials with finite-sample validity. In the presence of heterogeneous treatment effects, it is often of interest to select a subgroup that benefits from the…

统计方法学 · 统计学 2025-04-29 Zijun Gao

Studies investigating the causal effects of spatially varying exposures on outcomes often rely on observational and spatially indexed data. A prevalent challenge is unmeasured spatial confounding, where an unobserved spatially varying…

统计方法学 · 统计学 2025-11-19 Sophie M. Woodward , Mauricio Tec , Francesca Dominici

Methods have been developed for Mendelian randomization that can obtain consistent causal estimates while relaxing the instrumental variable assumptions. These include multivariable Mendelian randomization, in which a genetic variant may be…

统计方法学 · 统计学 2017-08-02 Jessica M. B. Rees , Angela Wood , Stephen Burgess

\noindent Randomized nomination sampling (RNS) is a rank-based sampling technique which has been shown to be effective in several nonparametric studies involving environmental and ecological applications. In this paper, we investigate…

统计方法学 · 统计学 2015-12-18 Mohammad Nourmohammadi , Mohammad Jafari Jozani , Brad Johnson

Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV…

统计方法学 · 统计学 2025-09-23 Zhonghua Liu , Baoluo Sun , Ting Ye , David Richardson , Eric Tchetgen Tchetgen

The use of machine learning (ML) in high-stakes societal decisions has encouraged the consideration of fairness throughout the ML lifecycle. Although data integration is one of the primary steps to generate high quality training data, most…

机器学习 · 计算机科学 2022-04-01 Sainyam Galhotra , Karthikeyan Shanmugam , Prasanna Sattigeri , Kush R. Varshney

This article considers Bayesian model selection via mean-field (MF) variational approximation. Towards this goal, we study the non-asymptotic properties of MF inference under the Bayesian framework that allows latent variables and model…

统计方法学 · 统计学 2023-12-29 Yangfan Zhang , Yun Yang

With nonignorable nonresponse, an effective method to construct valid estimators of population parameters is to use a covariate vector called instrument that can be excluded from the nonresponse propensity but are still useful covariate…

统计方法学 · 统计学 2025-09-17 Ji Chen , Jun Shao

Empirical researchers are often interested in not only whether a treatment affects an outcome of interest, but also how the treatment effect arises. Causal mediation analysis provides a formal framework to identify causal mechanisms through…

计量经济学 · 经济学 2022-02-01 Bora Kim

We introduce the Multiplicative Quasi-Instrumental Variable (MQIV) model, a framework for causal inference with unmeasured confounding that leverages an instrument that may be imperfectly exogenous. We allow the candidate quasi-instrument…

统计方法学 · 统计学 2026-05-13 Jiewen Liu , Chan Park , David Richardson , Eric J. Tchetgen Tchetgen

This dissertation focuses on modern causal inference under uncertainty and data restrictions, with applications to neoadjuvant clinical trials, distributed data networks, and robust individualized decision making. In the first project, we…

统计方法学 · 统计学 2023-01-24 Xiaoqing Tan

A major limitation of machine learning (ML) prediction models is that they recover associational, rather than causal, predictive relationships between variables. In high-stakes automation applications of ML this is problematic, as the model…

机器学习 · 计算机科学 2025-11-04 Jianqiao Mao , Max A. Little
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