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In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming…

Diabetic retinopathy (DR) is a leading cause of vision loss worldwide, and early diagnosis through automated retinal image analysis can significantly reduce the risk of blindness. This paper presents a robust deep learning framework for…

Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

Diabetic retinopathy (DR) is a leading cause of preventable blindness worldwide, demanding accurate automated diagnostic systems. While general-domain vision-language models like Contrastive Language-Image Pre-Training (CLIP) perform well…

As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments. As clinical trials in AD increasingly focus on…

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

In this paper, an ensemble-based method for the screening of diabetic retinopathy (DR) is proposed. This approach is based on features extracted from the output of several retinal image processing algorithms, such as image-level (quality…

Imaging methods by using computer techniques provide doctors assistance at any time and relieve their workload, especially for iterative processes like identifying objects of interest such as lesions and anatomical structures from the…

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

In an era where the global population is aging significantly, cognitive impairments among the elderly have become a major health concern. The need for effective assistive technologies is clear, and facial recognition systems are emerging as…

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

We developed Macular, a simulation platform with a graphical interface, designed to produce in silico experiment scenarios for the retina and the primary visual system. A scenario consists of generating a three-dimensional structure with…

Diabetic retinopathy (DR) is one of the most common eye conditions among diabetic patients. However, vision loss occurs primarily in the late stages of DR, and the symptoms of visual impairment, ranging from mild to severe, can vary…

Diabetic retinopathy (DR) is the result of a complication of diabetes affecting the retina. It can cause blindness, if left undiagnosed and untreated. An ophthalmologist performs the diagnosis by screening each patient and analyzing the…

High perceptual quality and low distortion degree are two important goals in image restoration tasks such as super-resolution (SR). Most of the existing SR methods aim to achieve these goals by minimizing the corresponding yet conflicting…

Hallucination is a common issue in Multimodal Large Language Models (MLLMs), yet the underlying principles remain poorly understood. In this paper, we investigate which components of MLLMs contribute to object hallucinations. To analyze…

Diabetic Retinopathy is a global health problem, influences 100 million individuals worldwide, and in the next few decades, these incidences are expected to reach epidemic proportions. Diabetic Retinopathy is a subtle eye disease that can…

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…