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In growing active matter systems, a large collection of engineered or living autonomous units metabolize free energy and create order at different length scales as they proliferate and migrate collectively. One such example is bacterial…

软凝聚态物质 · 物理学 2021-06-15 Japinder Nijjer , Changhao Li , Qiuting Zhang , Haoran Lu , Sulin Zhang , Jing Yan

Biofilms are complex structures which are inhabited by numerous amount of different species of microorganisms. Due to their ubiquity, they influence human life on an everyday basis. It is therefore important to understand the interactions…

计算工程、金融与科学 · 计算机科学 2025-09-03 Felix Klempt , Hendrik Geisler , Meisam Soleimani , Philipp Junker

In Nature, liquids often circulate in channels textured with leaflets, cilia or porous walls that deform with the flow. These soft structures are optimized to passively control flows and inspire the design of novel microfluidic and soft…

软凝聚态物质 · 物理学 2020-08-19 Martin Brandenbourger , Adrien Dangremont , Rudolf Sprik , Corentin Coulais

Slicks are thin viscous films that can be found at the air--water interface of water bodies such as lakes, rivers and oceans. These micro-layers are enriched in surfactants, organic matter, and microorganisms, and exhibit steep physical and…

流体动力学 · 物理学 2025-10-30 Felipe A. Barros , Italo Salas , Enkeleida Lushi , Francisca Guzman-Lastra

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Biofilms, bacteria cells surrounded by a self-produced polymeric matrix, are common on medical devices and lead to many hospital infections. The biofilm lifecycle includes disassembly and dispersion, where bacteria clusters detach from the…

定量方法 · 定量生物学 2026-05-18 Yuehui Xu , Jasmine A. F. Kreig , Zhuoran Wang , Elizabeth J. Stewart , Rayanne A. Luke , Sarah D. Olson

Conspectus: The ability to navigate in chemical gradients, called chemotaxis, is crucial for the survival of microorganisms. It allows them to find food and to escape from toxins. Many microorganisms can produce the chemicals to which they…

软凝聚态物质 · 物理学 2018-10-03 Benno Liebchen , Hartmut Löwen

Bacterial colonies are abundant on living and nonliving surfaces and are known to mediate a broad range of processes in ecology, medicine, and industry. Although extensively researched, from single cells to demographic scales, a…

软凝聚态物质 · 物理学 2018-09-14 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development and depends on complex biomechanical interactions between the biofilm and the underlying substrate. Changes in the physical…

生物物理 · 物理学 2021-03-16 Merrill Asp , Minh Tri Ho Thanh , Arvind Gopinath , Alison E. Patteson

Artificial microswimmers are a new technology with promising microfluidics and biomedical applications, such as directed cargo transport, microscale assembly, and targeted drug delivery. A fundamental barrier to realising this potential is…

流体动力学 · 物理学 2018-06-27 Thomas D. Montenegro-Johnson

We present a new methodology for efficient and high-quality patterning of biological reagents for surface-based biological assays. The method relies on hydrodynamically confined nanoliter volumes of reagents to interact with the substrate…

生物大分子 · 定量生物学 2016-04-27 J. Autebert , J. F. Cors , David P. Taylor , G. V. Kaigala

Dense suspensions of swimming bacteria are known to exhibit collective behaviour arising from the interplay of steric and hydrodynamic interactions. Unconfined suspensions exhibit transient, recurring vortices and jets, whereas those…

生物物理 · 物理学 2016-07-04 Hugo Wioland , Enkeleida Lushi , Raymond E. Goldstein

The acoustofluidic method holds great promise for manipulating microorganisms. When exposed to the steady vortex structures of acoustic streaming flow, these microorganisms exhibit intriguing dynamic behaviors, such as hydrodynamic trapping…

流体动力学 · 物理学 2025-04-25 Xuyang Sun , Wenchang Tan , Yi Man

We study the time evolution and driven motion of thin liquid films lying on top of chemical patterns on a substrate. Lattice-Boltzmann and molecular dynamics methods are used for simulations of the flow of microscopic and nanoscopic films,…

软凝聚态物质 · 物理学 2012-04-04 Fabian Dörfler , Markus Rauscher , Joel Koplik , Jens Harting , S. Dietrich

We use moving light patterns to control the motion of {\it Escherichia coli} bacteria whose motility is photo-activated. Varying the pattern speed controls the magnitude and direction of the bacterial flux, and therefore the accumulation of…

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

机器学习 · 计算机科学 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Quantifying the action of antibiotics on biofilms is essential to devise therapies against chronic infections. Biofilms are bacterial communities attached to moist surfaces, sheltered from external aggressions by a polymeric matrix.…

生物物理 · 物理学 2017-05-30 Bjorn Birnir , Ana Carpio , Elena Cebrian , Perfecto Vidal

A hallmark of bacterial populations cultured in vitro is their homogeneity of growth, where the majority of cells display identical growth rate, cell size and content. Recent insights, however, have revealed that even cells growing in…

定量方法 · 定量生物学 2022-06-07 Santosh Pandey , Yunsoo Park , Ankita Ankita , Gregory J. Phillips

The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to…

流体动力学 · 物理学 2011-03-16 A. Rathgeber , C. Strobl , H. -J. Kutschera , A. Wixforth

We study theoretically the evaporation-driven phase separation of a binary fluid mixture in a thin film deposited on a moving substrate, as occurs in meniscus-guided deposition for solution-processed materials. Our focus is on rapid…

软凝聚态物质 · 物理学 2024-07-01 René de Bruijn , Anton A. Darhuber , Jasper J. Michels , Paul van der Schoot