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We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

机器学习 · 计算机科学 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

Acute brain dysfunctions (ABD), which include coma and delirium, are prevalent in the ICU, especially among older patients. The current approach in manual assessment of ABD by care providers may be sporadic and subjective. Hence, there…

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

机器学习 · 计算机科学 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

Patients resuscitated from cardiac arrest who enter a coma are at high risk of death. Forecasting neurological outcomes of these patients (the task of neurological prognostication) could help with treatment decisions. In this paper, we…

信号处理 · 电气工程与系统科学 2023-12-04 Xiaobin Shen , Jonathan Elmer , George H. Chen

Accurate predictive models are crucial for analysing COVID-19 mortality trends. This study evaluates the impact of a custom data preprocessing pipeline on ten machine learning models predicting COVID-19 mortality using data from Our World…

机器学习 · 计算机科学 2026-02-27 Sangita Das , Subhrajyoti Maji

Purpose: Summarize ICU delirium prediction models published within the past five years. Methods: Electronic searches were conducted in April 2019 using PubMed, Embase, Cochrane Central, Web of Science, and CINAHL to identify peer reviewed…

Correlated survival data are prevalent in various clinical settings and have been extensively discussed in literature. One of the most common types of correlated survival data is clustered survival data, where the survival times from…

统计方法学 · 统计学 2024-08-02 Chengqian Xian , Camila P. E. de Souza , Wenqing He , Felipe F. Rodrigues , Renfang Tian

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst…

机器学习 · 计算机科学 2019-08-14 Supreeth P. Shashikumar , Christopher Josef , Ashish Sharma , Shamim Nemati

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

机器学习 · 计算机科学 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Motivated by an observational study of the effect of hospital ward versus intensive care unit admission on severe sepsis mortality, we develop methods to address two common problems in observational studies: (1) when there is a lack of…

应用统计 · 统计学 2015-08-13 Colin B. Fogarty , Mark E. Mikkelsen , David F. Gaieski , Dylan S. Small

Recent advances in causal inference techniques, more specifically, in the theory of structural causal models, provide the framework for identification of causal effects from observational data in the cases where the causal graph is…

机器学习 · 计算机科学 2020-10-29 Md Osman Gani , Shravan Kethireddy , Marvi Bikak , Paul Griffin , Mohammad Adibuzzaman

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

Lung cancer patients frequently experience breakthrough pain episodes, with up to 91% requiring timely intervention. To enable proactive pain management, we propose a hybrid machine learning and large language model pipeline that predicts…

Acute kidney injury (AKI) is a common and serious complication after a surgery which is associated with morbidity and mortality. The majority of existing perioperative AKI risk score prediction models are limited in their generalizability…

Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…

计算机与社会 · 计算机科学 2017-11-20 Anand Avati , Kenneth Jung , Stephanie Harman , Lance Downing , Andrew Ng , Nigam H. Shah

Delirium is an acute confusional state that has been shown to affect up to 31% of patients in the intensive care unit (ICU). Early detection of this condition could lead to more timely interventions and improved health outcomes. While…

Trauma mortality results from a multitude of non-linear dependent risk factors including patient demographics, injury characteristics, medical care provided, and characteristics of medical facilities; yet traditional approach attempted to…

机器学习 · 计算机科学 2020-09-11 Joshua D. Cardosi , Herman Shen , Jonathan I. Groner , Megan Armstrong , Henry Xiang

We develop and analyze explainable machine learning (ML) models for sepsis outcome prediction using a novel Electronic Health Record (EHR) dataset from 12,286 hospitalizations at a large emergency hospital in Romania. The dataset includes…

机器学习 · 计算机科学 2026-04-07 Andrei-Alexandru Bunea , Ovidiu Ghibea , Dan-Matei Popovici , Ion Daniel , Octavian Andronic

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

机器学习 · 计算机科学 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

Acute myocardial infarction (AMI) is one of the most severe manifestation of coronary artery disease. ST-segment elevation myocardial infarction (STEMI) is the most serious type of AMI. We proposed to develop a machine learning algorithm…

定量方法 · 定量生物学 2022-11-29 Ding Tao , Chen Liu , Shihan Wan
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