相关论文: Topology and morphology of self-deforming active s…
Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…
Active matter embraces systems that self-organize at different length and time scales, often exhibiting turbulent flows. Here, we use a quasi-two-dimensional nematically ordered layer of a protein-based active gel to experimentally…
The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…
Topological defects in active polar fluids exhibit complex dynamics driven by internally generated stresses, reflecting the deep interplay between topology, flow, and non-equilibrium hydrodynamics. Feedback control offers a powerful means…
We investigate how thin structures change their shape in response to non-mechanical stimuli that can be interpreted as variations in the structure's natural curvature. Starting from the theory of non-Euclidean plates and shells, we derive…
During the early-stages of embryo development, morphogenesis--- the emergence of shape and form in living organisms--- is almost exclusively associated with monolayers of tightly bound epithelial cells. To understand how such tissues change…
We study emergent dynamics in a viscous drop subject to interfacial nematic activity. Using hydrodynamic simulations, we show how the interplay of nematodynamics, activity-driven flows and surface deformations gives rise to a sequence of…
We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with additional, far-reaching implications…
We derive an asymptotically consistent morphoelastic shell model to describe the finite deformations of biological tissues using the variational asymptotical method. Biological materials may exhibit remarkable compressibility when under…
We review progress in active hydrodynamic descriptions of flowing media on curved and deformable manifolds: the state-of-the-art in continuum descriptions of single-layers of epithelial and/or other tissues during development. First, after…
Self-propulsion and navigation due to the sensing of environmental conditions - such as durotaxis and chemotaxis - are remarkable properties of biological cells that cannot be reproduced by single-component self-propelled particles. We…
The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that…
When considering flows in biological membranes, they are usually treated as flat, though more often than not, they are curved surfaces, even extremely curved, as in the case of the endoplasmic reticulum. Here, we study the topological…
We consider active nematodynamics on deformable surfaces. Based on a thermodynamically consistent surface Beris-Edwards model we add nematic activity and focus on the emerging additional coupling mechanism between the nematic field, the…
We study the kinematics and dynamics of a highly compliant membrane disk placed head-on in a uniform flow. With increasing flow velocity, the membrane deforms nonlinearly into increasingly parachute-like shapes. These aerodynamically…
Large deformations play a central role in the shape transformations of slender active and biological structures. A classical example is the eversion of the Volvox embryo, which demonstrates the need for shell theories that can describe…
The persistent dynamics in systems out of equilibrium, particularly those characterized by annihilation and creation of topological defects, is known to involve complicated spatiotemporal processes and is deemed difficult to control. Here…
The ordering of rod-like particles in soft, deformable containers emerges from the interplay of anisotropic interactions, geometric confinement, and boundary compliance. This competition couples internal particle organization to container…
We study phase separation between coexisting active and passive fluids in three-dimensions, using numerical simulation and experiments. Chaotic flows of the active phase drive giant interfacial deformations, causing the co-existing phases…
Topological defects are ubiquitous on surfaces with orientational order fields. Here, we study equilibrium states generated by the feedback between geometry and nematic order on fluid membranes with an integer topological defect. When the…