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Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

软凝聚态物质 · 物理学 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

We systematically explore the self-assembly of semi-flexible polymers in deformable spherical confinement across a wide regime of chain stiffness, contour lengths and packing fractions by means of coarse-grained molecular dynamics…

软凝聚态物质 · 物理学 2021-07-12 Maxime M. C. Tortora , Daniel Jost

We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…

软凝聚态物质 · 物理学 2018-05-18 Wen-de Tian , Yong-kun Guo , Kang Chen , Yu-qiang Ma

Shells, when confined, can deform in a broad assortment of shapes and patterns, often quite dissimilar to what is produced by their flat counterparts (plates). In this work we discuss the morphological landscape of shells deposited on a…

软凝聚态物质 · 物理学 2018-06-12 Octavio Albarrán , Desislava V. Todorova , Eleni Katifori , Lucas Goehring

Liquid shells (e.g. double emulsions, vesicles etc.) are susceptible to interfacial instability and rupturing when driven out of mechanical equilibrium. This poses a significant challenge for the design of liquid shell based micro-machines,…

软凝聚态物质 · 物理学 2019-10-30 Babak Vajdi Hokmabad , Kyle A. Baldwin , Carsten Krüger , Christian Bahr , Corinna C. Maass

Morphogenesis involves the transformation of initially simple shapes, such as multicellular spheroids, into more complex $3D$ shapes. These shape changes are governed by mechanical forces including molecular motor-generated forces as well…

软凝聚态物质 · 物理学 2023-10-13 Ajoy Maji , Kinjal Dasbiswas , Yitzhak Rabin

Topological defects play a prominent role in the physics of two-dimensional materials. When driven out of equilibrium in active nematics, disclinations can acquire spontaneous self-propulsion and drive self-sustained flows upon…

软凝聚态物质 · 物理学 2019-12-06 Suraj Shankar , M. Cristina Marchetti

Epithelial monolayers are a central building block of complex organisms. Topological defects have emerged as important elements for single cell behavior in flat epithelia. Here we theoretically study such defects in a three-dimensional…

生物物理 · 物理学 2025-02-19 Oliver M. Drozdowski , Ulrich S. Schwarz

We describe the flows and morphological dynamics of topological defect lines and loops in three-dimensional active nematics and show, using theory and numerical modelling, that they are governed by the local profile of the orientational…

软凝聚态物质 · 物理学 2020-03-13 Jack Binysh , Žiga Kos , Simon Čopar , Miha Ravnik , Gareth P. Alexander

Point-like motile topological defects control the universal dynamics of diverse two-dimensional active nematics ranging from shaken granular rods to cellular monolayers. A comparable understanding in higher dimensions has yet to emerge. We…

Morphological trends in growing colonies of living cells are at the core of physiological and evolutionary processes. Using active gel equations, which include cell division, we show that shape changes during the growth can be regulated by…

软凝聚态物质 · 物理学 2016-07-27 Amin Doostmohammadi , Sumesh P. Thampi , Julia M. Yeomans

Colloidal gels are prime examples of functional materials exhibiting disordered, amorphous, yet meta-stable forms. They maintain stability through short-range attractive forces and their material properties are tunable by external forces.…

We use numerical simulations to show how noninteracting hard particles binding to a deformable elastic shell may self-assemble into a variety of linear patterns. This is a result of the nontrivial elastic response to deformations of shells.…

软凝聚态物质 · 物理学 2011-02-25 Andela Šarić , Angelo Cacciuto

Topological defects are distinctive signatures of liquid crystals. They profoundly affect the viscoelastic behavior of the fluid by constraining the orientational structure in a way that inevitably requires global changes not achievable…

软凝聚态物质 · 物理学 2015-06-19 Luca Giomi , Mark J. Bowick , Prashant Mishra , Rastko Sknepnek , M. Cristina Marchetti

Living systems are chiral on multiple scales, from constituent biopolymers to large scale morphology, and their active mechanics is both driven by chiral components and serves to generate chiral morphologies. We describe the mechanics of…

软凝聚态物质 · 物理学 2023-07-03 Sami C. Al-Izzi , Gareth P. Alexander

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

软凝聚态物质 · 物理学 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

Active materials are capable of converting free energy into directional motion, giving rise to striking dynamical phenomena. Developing a general understanding of their structure in relation to the underlying non-equilibrium physics would…

软凝聚态物质 · 物理学 2018-10-17 Nitin Kumar , Rui Zhang , Juan J. de Pablo , Margaret L. Gardel

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

软凝聚态物质 · 物理学 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger

From the Golgi apparatus to endosomes, organelles in the endomembrane system exhibit complex and varied morphologies that are often related to their function. Such membrane-bound organelles operate far from equilibrium due to directed…

软凝聚态物质 · 物理学 2024-11-27 S. Alex Rautu , Richard G. Morris , Madan Rao

Topological phenomena typically govern the behavior of delocalized waves, giving rise to robust transport in electronic, photonic, and mechanical systems. Whether similar principles can directly control the motion of a localized particle,…

流体动力学 · 物理学 2026-03-13 Ethan Andersson , Valeri Frumkin