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Research on chemotherapy, heart surgery, and vaccines has indicated that the risks and benefits of a treatment could vary depending on the time of day it is administered. A challenge with performing studies on timing treatment…

应用统计 · 统计学 2025-04-10 Michael T. Gorczyca , Tavish M. McDonald , Brandon Oppong-Antwi

Understanding the sleep quality and architecture is essential to human being's health, which is usually represented using multiple sleep stages. A standard sleep stage determination requires Electroencephalography (EEG) signals during the…

信号处理 · 电气工程与系统科学 2019-09-26 Yuezhou Zhang , Zhicheng Yang , Ke Lan , Xiaoli Liu , Zhengbo Zhang , Peiyao Li , Desen Cao , Jiewen Zheng , Jianli Pan

Drowsiness can put lives of many drivers and workers in danger. It is important to design practical and easy-to-deploy real-world systems to detect the onset of drowsiness.In this paper, we address early drowsiness detection, which can…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Reza Ghoddoosian , Marnim Galib , Vassilis Athitsos

The circadian clock is an internal timer that coordinates the daily rhythms of behavior and physiology, including sleep and hormone secretion. Accurately tracking the state of the circadian clock, or circadian phase, holds immense potential…

动力系统 · 数学 2023-06-14 Dae Wook Kim , Minki P. Lee , Daniel B. Forger

Characterizing the sleep-wake cycle in adolescents is an important prerequisite to better understand the association of abnormal sleep patterns with subsequent clinical and behavioral outcomes. The aim of this research was to develop hidden…

应用统计 · 统计学 2022-12-22 Semhar B. Ogbagaber , Yifan Cui , Kaigang Li , Ronald J. Iannotti , Paul S. Albert

Sleep is essential for the maintenance of the brain and the body, yet many features of sleep are poorly understood and mathematical models are an important tool for probing proposed biological mechanisms. The most well-known mathematical…

神经元与认知 · 定量生物学 2015-06-17 Anne C. Skeldon , Derk-Jan Dijk , Gianne Derks

For quantitative evaluation of sleep disturbances, a noninvasive monitoring system is developed by introducing an event-based method. We observe sleeping in home context and classify the sleep disturbances into three types of events: motion…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Lyn Chao-ling Chen , Kuan-Wen Chen , Yi-Ping Hung

A biophysical model of arousal dynamics is used to study mechanisms of synchronisation and loss of synchrony among the three key oscillators controlling sleep-wake cycles: the circadian, homeostatic, and light oscillators. Synchronisation…

生物物理 · 物理学 2021-01-22 Dmitry E. Postnov , Ksenia O. Merkulova , Svetlana Postnova

Gene expression levels, hormone secretion, and internal body temperature each oscillate over an approximately 24-hour cycle, or display circadian rhythms. Many circadian biology studies have investigated how these rhythms vary across…

Closed-loop sleep modulation is an emerging research paradigm to treat sleep disorders and enhance sleep benefits. However, two major barriers hinder the widespread application of this research paradigm. First, subjects often need to be…

信号处理 · 电气工程与系统科学 2022-11-24 Mingzhe Sun , Aaron Zhou , Naize Yang , Yaqian Xu , Yuhan Hou , Xilin Liu

In this paper, we propose a novel method and a practical approach to predicting early onsets of sleep syndromes, including restless leg syndrome, insomnia, based on an algorithm that is comprised of two modules. A Fast Fourier Transform is…

神经元与认知 · 定量生物学 2021-07-09 Tim Cvetko , Tinkara Robek

Sleep detection and annotation are crucial for researchers to understand sleep patterns, especially in children. With modern wrist-worn watches comprising built-in accelerometers, sleep logs can be collected. However, the annotation of…

信号处理 · 电气工程与系统科学 2023-12-14 Ashwin Ram , Sundar Sripada V. S. , Shuvam Keshari , Zizhe Jiang

Much attention has been given to automatic sleep staging algorithms in past years, but the detection of discrete events in sleep studies is also crucial for precise characterization of sleep patterns and possible diagnosis of sleep…

信号处理 · 电气工程与系统科学 2020-04-14 Alexander Neergaard Olesen , Stanislas Chambon , Valentin Thorey , Poul Jennum , Emmanuel Mignot , Helge B. D. Sorensen

This paper presents MIS-LSTM, a hybrid framework that joins CNN encoders with an LSTM sequence model for sleep quality and stress prediction at the day level from multimodal lifelog data. Continuous sensor streams are first partitioned into…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Seongwan Park , Jieun Woo , Siheon Yang

Humans spend vast hours in bed -- about one-third of the lifetime on average. Besides, a human at rest is vital in many healthcare applications. Typically, humans are covered by a blanket when resting, for which we propose a multimodal…

计算机视觉与模式识别 · 计算机科学 2020-12-15 Yu Yin , Joseph P. Robinson , Yun Fu

Cortical arousals are transient events of disturbed sleep that occur spontaneously or in response to stimuli such as apneic events. The gold standard for arousal detection in human polysomnographic recordings (PSGs) is manual annotation by…

The cosinor model is frequently used to represent the oscillatory behavior of different genes over time. When data are collected from multiple individuals, the cosinor model is estimated with recorded gene expression levels and the 24 hour…

应用统计 · 统计学 2024-07-18 Michael T. Gorczyca

We study downlink (DL) channel estimation in a multi-cell Massive multiple-input multiple-output (MIMO) system operating in a time-division duplex. The users must know their effective channel gains to decode their received DL data signals.…

信息论 · 计算机科学 2021-09-07 Amin Ghazanfari , Trinh Van Chien , Emil Björnson , Erik G. Larsson

Circadian disruption contributes to adverse effects on sleep, performance, and health. One accepted method to track continuous daily changes in circadian timing is to measure core body temperature (CBT), and establish daily,…

Sleep constitutes a key indicator of human health, performance, and quality of life. Sleep deprivation has long been related to the onset, development, and worsening of several mental and metabolic disorders, constituting an essential…

信号处理 · 电气工程与系统科学 2023-01-25 María Martínez-García , Fernando Moreno-Pino , Pablo M. Olmos , Antonio Artés-Rodríguez
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