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相关论文: Learning Multimorbidity Patterns from Electronic H…

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Chronic diseases frequently co-occur in patterns that are unlikely to arise by chance, a phenomenon known as multimorbidity. This growing challenge for patients and healthcare systems is amplified by demographic aging and the rising burden…

物理与社会 · 物理学 2025-10-14 Johanna Einsiedler , Katharina Ledebur , Peter Klimek , Laust Hvas Mortensen

Non-negative matrix factorization (NMF) is a prob- lem with many applications, ranging from facial recognition to document clustering. However, due to the variety of algorithms that solve NMF, the randomness involved in these algorithms,…

数值分析 · 数学 2018-12-17 Connor Sell , Jeremy Kepner

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with…

机器学习 · 计算机科学 2023-06-07 Xinlu Zhang , Shiyang Li , Zhiyu Chen , Xifeng Yan , Linda Petzold

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

机器学习 · 计算机科学 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

机器学习 · 计算机科学 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Nonnegative Matrix Factorization (NMF) is a widely used technique for data representation. Inspired by the expressive power of deep learning, several NMF variants equipped with deep architectures have been proposed. However, these methods…

机器学习 · 计算机科学 2017-11-21 Yuning Qiu , Guoxu Zhou , Kan Xie

The availability of large and deep electronic healthcare records (EHR) datasets has the potential to enable a better understanding of real-world patient journeys, and to identify novel subgroups of patients. ML-based aggregation of EHR data…

机器学习 · 计算机科学 2022-08-03 Owen Parsons , Nathan E Barlow , Janie Baxter , Karen Paraschin , Andrea Derix , Peter Hein , Robert Dürichen

Objectives: The fee-for-service approach to healthcare leads to the management of a patient's conditions in an independent manner, inducing various negative consequences. It is recognized that a bundled care approach to healthcare-one that…

计算机与社会 · 计算机科学 2017-06-05 You Chen , Abel N. Kho , David Liebovitz , Catherine Ivory , Sarah Osmundson , Jiang Bian , Bradley A. Malin

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

Cancer, with its inherent heterogeneity, is commonly categorized into distinct subtypes based on unique traits, cellular origins, and molecular markers specific to each type. However, current studies primarily rely on complete multi-omics…

机器学习 · 计算机科学 2024-11-26 Yingxuan Ren , Fengtao Ren , Bo Yang

Integrating multimodal Electronic Health Records (EHR) data, such as numerical time series and free-text clinical reports, has great potential in predicting clinical outcomes. However, prior work has primarily focused on capturing temporal…

机器学习 · 计算机科学 2025-11-10 Fuying Wang , Feng Wu , Yihan Tang , Lequan Yu

Multimorbidity research in mental health services requires data from physical health conditions which is traditionally limited in mental health care electronic health records. In this study, we aimed to extract data from physical health…

Clustering on the data with multiple aspects, such as multi-view or multi-type relational data, has become popular in recent years due to their wide applicability. The approach using manifold learning with the Non-negative Matrix…

机器学习 · 计算机科学 2020-09-08 Khanh Luong , Richi Nayak

In this work, we apply topic modeling using Non-Negative Matrix Factorization (NMF) on the COVID-19 Open Research Dataset (CORD-19) to uncover the underlying thematic structure and its evolution within the extensive body of COVID-19…

计算与语言 · 计算机科学 2025-03-25 Divya Patel , Vansh Parikh , Om Patel , Agam Shah , Bhaskar Chaudhury

Electronic medical records (EMRs) supports the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But insofar most algorithms have been centralized,…

机器学习 · 计算机科学 2019-03-25 Li Huang , Dianbo Liu

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

机器学习 · 计算机科学 2021-11-10 Ziyi Liu , Jiaqi Zhang , Yongshuai Hou , Xinran Zhang , Ge Li , Yang Xiang

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

医学物理 · 物理学 2020-06-17 Changhee Lee , Mihaela van der Schaar

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

机器学习 · 统计学 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah