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Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…

基因组学 · 定量生物学 2024-08-02 Boyi Guo , Wodan Ling , Sang Ho Kwon , Pratibha Panwar , Shila Ghazanfar , Keri Martinowich , Stephanie C. Hicks

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…

应用统计 · 统计学 2008-07-30 Xiaoxi Zhang , Timothy D. Johnson , Roderick J. A. Little , Yue Cao

A novel multi-focus image fusion algorithm performed in spatial domain based on similarity characteristics is proposed incorporating with region segmentation. In this paper, a new similarity measure is developed based on the structural…

计算机视觉与模式识别 · 计算机科学 2022-02-01 Ya-Qiong Zhang , Xiao-Jun Wu , Hui Li

In medical imaging, radiological scans of different modalities serve to enhance different sets of features for clinical diagnosis and treatment planning. This variety enriches the source information that could be used for outcome…

图像与视频处理 · 电气工程与系统科学 2020-06-01 William Le , Francisco Perdigón Romero , Samuel Kadoury

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

定量方法 · 定量生物学 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

Objectives: Analyze the types of studies and algorithms that are most applied, Identify the anatomical regions treated. Determine the application of parallel techniques used in studies carried out between 2010 and 2022 in research on noise…

图像与视频处理 · 电气工程与系统科学 2023-01-05 Sussana M. Florez-Aroni , Mijail A. Hancco-Condori , Fred Torres-Cruz

Perfusion MRI (pMRI) offers valuable insights into tumor vascularity and promises to predict tumor genotypes, thus benefiting prognosis for glioma patients, yet effective models tailored to 4D pMRI are still lacking. This study presents the…

图像与视频处理 · 电气工程与系统科学 2024-06-11 Ruodan Yan , Carola-Bibiane Schönlieb , Chao Li

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

医学物理 · 物理学 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

Contemporary interventional imaging lacks the real-time 3D guidance needed for the precise localization of mobile thoracic targets. While Cone-Beam CT (CBCT) provides 3D data, it is often too slow for dynamic motion tracking. Deep learning…

医学物理 · 物理学 2025-11-19 Fawazilla Utomo , Tess Reynolds , Nicholas Hindley

Radiation therapy (RT) is essential in treating head and neck cancer (HNC), with magnetic resonance imaging(MRI)-guided RT offering superior soft tissue contrast and functional imaging. However, manual tumor segmentation is time-consuming…

图像与视频处理 · 电气工程与系统科学 2024-11-25 Nikoo Moradi , André Ferreira , Behrus Puladi , Jens Kleesiek , Emad Fatemizadeh , Gijs Luijten , Victor Alves , Jan Egger

Purpose: Tumor-associated vasculature differs from healthy blood vessels by its chaotic architecture and twistedness, which promotes treatment resistance. Measurable differences in these attributes may help stratify patients by likely…

Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. However, there is growing concern about GBCA toxicity. This…

图像与视频处理 · 电气工程与系统科学 2024-09-04 Zach Eidex , Mojtaba Safari , Richard L. J. Qiu , David S. Yu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Diagnosis of liver infection at preliminary stage is important for better treatment. In todays scenario devices like sensors are used for detection of infections. Accurate classification techniques are required for automatic identification…

机器学习 · 计算机科学 2015-02-20 Kalyan Nagaraj , Amulyashree Sridhar

Randomized Controlled Trials (RCTs) are the gold standard for comparing the effectiveness of a new treatment to the current one (the control). Most RCTs allocate the patients to the treatment group and the control group by uniform…

机器学习 · 统计学 2018-10-22 Onur Atan , William R. Zame , Mihaela van der Schaar

Head and neck squamous cell carcinoma (HNSCC) presents significant challenges in clinical oncology due to its heterogeneity and high mortality rates. This study aims to leverage clinical data and machine learning (ML) principles to predict…

定量方法 · 定量生物学 2025-02-18 Naman Dhariwal , Abeyankar Giridharan

Head and Neck (H\&N) organ-at-risk (OAR) and tumor segmentations are essential components of radiation therapy planning. The varying anatomic locations and dimensions of H\&N nodal Gross Tumor Volumes (GTVn) and H\&N primary gross tumor…

图像与视频处理 · 电气工程与系统科学 2022-11-01 Abhishek Srivastava , Debesh Jha , Bulent Aydogan , Mohamed E. Abazeed , Ulas Bagci

The variability introduced by differences in MRI scanner models, acquisition protocols, and imaging sites hinders consistent analysis and generalizability across multicenter studies. We present a novel image-based harmonization framework…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Luca Caldera , Lara Cavinato , Francesca Ieva

During and after a course of therapy, imaging is routinely used to monitor the disease progression and assess the treatment responses. Despite of its significance, reliably capturing and predicting the spatial-temporal anatomic changes from…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Liang Qiu , Liyue Shen , Lianli Liu , Junyan Liu , Yizheng Chen , Lei Xing

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

计算机视觉与模式识别 · 计算机科学 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke