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In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

神经元与认知 · 定量生物学 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

神经元与认知 · 定量生物学 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Human brain dynamics can be profitably viewed through the lens of statistical mechanics, where neurophysiological activity evolves around and between local attractors representing preferred mental states. Many physically-inspired models of…

神经元与认知 · 定量生物学 2016-09-06 Arian Ashourvan , Shi Gu , Marcelo G. Mattar , Jean M. Vettel , Danielle S. Bassett

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

机器学习 · 计算机科学 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Today the human brain can be modeled as a graph where nodes represent different regions and links stand for statistical interactions between their activities as recorded by different neuroimaging techniques. Empirical studies have lead to…

神经元与认知 · 定量生物学 2017-11-01 J. H. Martínez , J. M. Buldú , D. Papo , F. De Vico Fallani , M. Chavez

Understanding the intricate architecture of brain networks and its connection to brain function is essential for deciphering the underlying principles of cognition and disease. While traditional graph-theoretical measures have been widely…

混沌动力学 · 物理学 2025-11-13 Anca Radulescu , Eva Kaslik , Alexandru Fikl , Johan Nakuci , Sarah Muldoon , Michael Anderson

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

神经元与认知 · 定量生物学 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

Understanding the relationship between the structure and function of the human brain is one of the most important open questions in Neurosciences. In particular, Resting State Networks (RSN) and more specifically the Default Mode Network…

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

神经元与认知 · 定量生物学 2013-04-16 Gaël Varoquaux , R. C. Craddock

How human brain function emerges from structure has intrigued researchers for decades and numerous models have been put forward, yet none of them yields a close structure-function relation. Here we present a resonance model based on…

神经元与认知 · 定量生物学 2022-10-10 Yanjiang Wang , Jichao Ma , Jiebin Luo , Xue Chen , Yue Yuan

The study of dynamic functional connectomes has provided valuable insights into how patterns of brain activity change over time. Neural networks process information through artificial neurons, conceptually inspired by patterns of activation…

神经元与认知 · 定量生物学 2025-08-12 Yutong Wu , Peilin He , Tananun Songdechakraiwut

Unraveling how macroscopic cognitive phenotypes emerge from microscopic neuronal connectivity remains one of the core pursuits of neuroscience. To this end, researchers typically leverage multi-modal information from structural connectivity…

人工智能 · 计算机科学 2026-02-03 Tianhao Huang , Guanghui Min , Zhenyu Lei , Aiying Zhang , Chen Chen

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

机器学习 · 计算机科学 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

神经元与认知 · 定量生物学 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

神经元与认知 · 定量生物学 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

In this paper, we consider stable stochastic linear systems modeling whole-brain resting-state dynamics. We parametrize the state matrix of the system (effective connectivity) in terms of its steady-state covariance matrix (functional…

系统与控制 · 电气工程与系统科学 2023-10-12 Umberto Casti , Giacomo Baggio , Danilo Benozzo , Sandro Zampieri , Alessandra Bertoldo , Alessandro Chiuso

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

应用统计 · 统计学 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the…

神经元与认知 · 定量生物学 2018-11-01 Gorka Zamora-López , Yuhan Chen , Gustavo Deco , Morten L. Kringelbach , Changsong Zhou

Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can…

神经元与认知 · 定量生物学 2015-06-22 Anca Radulescu , Sergio Verduzco-Flores