相关论文: Brain state stability during working memory is exp…

Neurons regulate the distribution of signaling components across an extended tree-like cellular structure using both local and global feedback control. This is hypothesized to allow homeostatic control of the electrical activity of a neuron…

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Dynamics of a chaotic spiking neuron model are being studied mathematically and experimentally. The Nonlinear Dynamic State neuron (NDS) is analysed to further understand the model and improve it. Chaos has many interesting properties such…

Neural circuits exhibit complex activity patterns, both spontaneously and evoked by external stimuli. Information encoding and learning in neural circuits depend on how well time-varying stimuli can control spontaneous network activity. We…

Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Cognitive control researchers aim to describe the processes that support adaptive cognition to achieve specific goals. Control theorists consider how to influence the state of systems to reach certain user-defined goals. In brain networks,…

Stroke-induced disturbances of large-scale cortical networks are known to be associated with the extent of motor deficits. We argue that identifying brain networks representative of motor behavior in the resting brain would provide…

We present a new paradigm in the study of brain mental dynamics on the basis of the stable transient activity neural networks observed in experiments. This new approach is in contrast to traditional system analysis usually adopted in…

Memories in the brain are separated in two categories: short-term and long-term memories. Long-term memories remain for a lifetime, while short-term ones exist from a few milliseconds to a few minutes. Within short-term memory studies,…

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Continuous attractor neural networks generate a set of smoothly connected attractor states. In memory systems of the brain, these attractor states may represent continuous pieces of information such as spatial locations and head directions…

The development of neuromorphic systems based on memristive elements - resistors with memory - requires a fundamental understanding of their collective dynamics when organized in networks. Here, we study an experimentally inspired model of…

The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

The neural network is a powerful computing framework that has been exploited by biological evolution and by humans for solving diverse problems. Although the computational capabilities of neural networks are determined by their structure,…

Models of the cortico-basal ganglia network and volume conductor models of the brain can provide insight into the mechanisms of action of deep brain stimulation (DBS). In this study, the coupling of a network model, under parkinsonian…

Changes in an animal's behavioral state, such as arousal and movements, induce {complex modulations of the baseline input currents to sensory areas, eliciting sensory modality-specific effects. A simple computational principle explaining…

The influence of the synaptic channel properties on the stability of delayed activity maintained by recurrent neural network is studied. The duration of excitatory post-synaptic current (EPSC) is shown to be essential for the global…