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We propose robust methods for inference on the effect of a treatment variable on a scalar outcome in the presence of very many controls. Our setting is a partially linear model with possibly non-Gaussian and heteroscedastic disturbances.…

统计方法学 · 统计学 2017-10-05 Alexandre Belloni , Victor Chernozhukov , Christian Hansen

The notion of hypothetical bias (HB) constitutes, arguably, the most fundamental issue in relation to the use of hypothetical survey methods. Whether or to what extent choices of survey participants and subsequent inferred estimates…

计量经济学 · 经济学 2021-09-08 Milad Haghani , Michiel C. J. Bliemer , John M. Rose , Harmen Oppewal , Emily Lancsar

The power of a large clinical trial can be adversely affected by low recruitment, follow-up and adherence rates. External pilot trials estimate these rates and use them, via pre-specified decision rules, to determine if the definitive trial…

统计方法学 · 统计学 2021-06-16 Duncan T. Wilson , Rebecca E. A. Walwyn , Julia Brown , Amanda J. Farrin

Randomized Controlled Trials (RCTs) are pivotal in generating internally valid estimates with minimal assumptions, serving as a cornerstone for researchers dedicated to advancing causal inference methods. However, extending these findings…

统计方法学 · 统计学 2024-05-28 Melody Y Huang , Harsh Parikh

The Global Precedence Effect (GPE) suggests that the processing of global properties of a visual stimulus precedes the processing of local properties. The generality of this theory was argued for four decades during different known…

计算机视觉与模式识别 · 计算机科学 2023-07-11 Zahra Rezvani , Ali Katanforoush , Richard van Wezel , Hamidreza Pouretemad

In estimating the causal effect of a continuous exposure or treatment, it is important to control for all confounding factors. However, most existing methods require parametric specification for how control variables influence the outcome…

应用统计 · 统计学 2020-07-21 Spencer Woody , Carlos M. Carvalho , P. Richard Hahn , Jared S. Murray

Beyond conditional average treatment effects, treatments may impact the entire outcome distribution in covariate-dependent ways, for example, by altering the variance or tail risks for specific subpopulations. We propose a novel estimand to…

机器学习 · 统计学 2026-03-18 Saksham Jain , Alex Luedtke

In nutritional and environmental epidemiology, exposures are impractical to measure accurately, while practical measures for these exposures are often subject to substantial measurement error. Regression calibration is among the most used…

统计方法学 · 统计学 2026-01-27 Zexiang Li , Donna Spiegelman , Molin Wang , Zuoheng Wang , Xin Zhou

External controls (ECs) from historical trials or real-world data have gained increasing attention as a way to augment hybrid and single-arm trials, especially when balanced randomization is infeasible. While most existing work has focused…

统计方法学 · 统计学 2025-12-15 Yujing Gao , Xiang Zhang , Shu Yang

Using administrative patient-care data such as Electronic Health Records (EHR) and medical/ pharmaceutical claims for population-based scientific research has become increasingly common. With vast sample sizes leading to very small standard…

统计方法学 · 统计学 2023-08-21 Ritoban Kundu , Xu Shi , Jean Morrison , Jessica Barrett , Bhramar Mukherjee

This paper concerns robust inference on average treatment effects following model selection. In the selection on observables framework, we show how to construct confidence intervals based on a doubly-robust estimator that are robust to…

统计理论 · 数学 2018-04-13 Max H. Farrell

It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treatment effect estimation involve ambiguous…

统计方法学 · 统计学 2025-03-28 Bo Liu , Laine Thomas , Rury R. Holman , Fan Li

This paper shows how to use a randomized saturation experimental design to identify and estimate causal effects in the presence of spillovers--one person's treatment may affect another's outcome--and one-sided non-compliance--subjects can…

The NLP community typically relies on performance of a model on a held-out test set to assess generalization. Performance drops observed in datasets outside of official test sets are generally attributed to "out-of-distribution" effects.…

计算与语言 · 计算机科学 2024-04-03 Aparna Elangovan , Jiayuan He , Yuan Li , Karin Verspoor

Analyses of voting algorithms often overlook informational externalities shaping individual votes. For example, pre-polling information often skews voters towards candidates who may not be their top choice, but who they believe would be a…

计算机科学与博弈论 · 计算机科学 2024-04-12 Yiling Chen , Jessie Finocchiaro

Genetic data are often used to infer demographic history and changes or detect genes under selection. Inferential methods are commonly based on models making various strong assumptions: demography and population structures are supposed…

种群与进化 · 定量生物学 2020-07-28 Clotilde Lepers , Sylvain Billiard , Matthieu Porte , Sylvie Méléard , Viet Chi Tran

Different statistical samples (e.g., from different locations) offer populations and learning systems observations with distinct statistical properties. Samples under (1) 'Unconfounded' growth preserve systems' ability to determine the…

统计方法学 · 统计学 2025-08-05 Andre F. Ribeiro

Causal inference is crucial for understanding the true impact of interventions, policies, or actions, enabling informed decision-making and providing insights into the underlying mechanisms that shape our world. In this paper, we establish…

统计方法学 · 统计学 2024-03-26 Jingyue Huang , Changbao Wu , Leilei Zeng

In observational studies, causal inference relies on several key identifying assumptions. One identifiability condition is the positivity assumption, which requires the probability of treatment be bounded away from 0 and 1. That is, for…

统计方法学 · 统计学 2022-02-21 Yaqian Zhu , Nandita Mitra , Jason Roy

In data analysis, unexpected results often prompt researchers to revisit their procedures to identify potential issues. While some researchers may struggle to identify the root causes, experienced researchers can often quickly diagnose…

统计方法学 · 统计学 2026-01-06 H. Sherry Zhang , Roger D. Peng