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Radiation therapy is an important tool in the treatment of breast cancer and can play a crucial role in improving patient outcomes. For breast cancer, if the technique has been for a long time the use of 3DCRT, clinicians have seen the…

Pancreatic cancer, characterized by its notable prevalence and mortality rates, demands accurate lesion delineation for effective diagnosis and therapeutic interventions. The generalizability of extant methods is frequently compromised due…

图像与视频处理 · 电气工程与系统科学 2025-05-06 Jun Li , Yijue Zhang , Haibo Shi , Minhong Li , Qiwei Li , Xiaohua Qian

A distinct feature of pancreatic ductal adenocarcinoma (PDAC) is a prominent tumor microenvironment (TME) with remarkable cellular and spatial heterogeneity that meaningfully impacts disease biology and treatment resistance. The dynamic…

Purpose: To introduce a simple system exploitation with the potential to turn MRI scanners into general-purpose RF motion monitoring systems. Methods: Inspired by Pilot Tone (PT), this work proposes Beat Pilot Tone (BPT), in which two or…

医学物理 · 物理学 2024-06-11 Suma Anand , Michael Lustig

Cancer is a heterogeneous disease and tumours of the same type can differ greatly at the genetic and phenotypic levels. Understanding how these differences impact sensitivity to treatment is an essential step towards patient-specific…

组织与器官 · 定量生物学 2023-02-28 Chloé Colson , Philip K. Maini , Helen M. Byrne

Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…

Over the last decade, there has been significant progress in the field of interactive virtual rehabilitation. Physical therapy (PT) stands as a highly effective approach for enhancing physical impairments. However, patient motivation and…

人机交互 · 计算机科学 2024-05-24 Pavan Uttej Ravva , Pinar Kullu , Mohammad Fahim Abrar , Roghayeh Leila Barmaki

We consider the effects of parameter uncertainty on the optimal radiation schedule in the context of the linear-quadratic model. Our interest arises from the observation that if inter-patient variations in OAR and tumor sensitivities to…

组织与器官 · 定量生物学 2015-06-05 Hamidreza Badri , Yoichi Watanabe , Kevin Leder

This study estimated the planning quality of intensity-modulated radiotherapy in 42 lung cancer cases to provide preliminary data for the development of a planning quality assurance algorithm. Organs in or near the thoracic cavity…

医学物理 · 物理学 2015-03-11 Jihye Koo , Myonggeun Yoon , Weon Kuu Chung , Dong Wook Kim

Papillary thyroid microcarcinoma (PTMC) is increasingly managed with radio-frequency ablation (RFA), yet accurate lesion segmentation in ultrasound videos remains difficult due to low contrast, probe-induced motion, and heat-related…

计算机视觉与模式识别 · 计算机科学 2025-10-22 Maryam Dialameh , Hossein Rajabzadeh , Jung Suk Sim , Hyock Ju Kwon

Stimulated Raman scattering (SRS) microscopy has emerged as a powerful technique for probing the spatiotemporal dynamics of molecular bonds with exceptional sensitivity, resolution, and speed. However, classically, its performance remains…

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

In radiation therapy tumor size, and thus also volume, has a significant impact on the local control of tumors. Moreover, tumor volume is a significant prognostic factor for modelling and predicting therapeutic outcomes in cancer treatment.…

医学物理 · 物理学 2023-03-21 Stephan Radonic , Jürgen Besserer , Jessica Kneubühl , Valeria Meier , Uwe Schneider

Objectives: MR elastography (MRE) offers valuable mechanical tissue characterization, however, in deep abdominal organs like the pancreas conventional single-driver, single-frequency approaches often fail. This study evaluates whether…

Background: Low-risk prostate cancer patients enrolled in active surveillance programs commonly undergo biopsies for examination of cancer progression. Biopsies are conducted as per a fixed and frequent schedule (e.g., annual biopsies).…

Radiopharmaceutical therapies (RPTs) present a major opportunity to improve cancer therapy. Although many current RPTs use the same injected activity for all patients, there is interest in using absorbed dose measurements to enable…

In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

While cancer has traditionally been considered a genetic disease, mounting evidence indicates an important role for non-genetic (epigenetic) mechanisms. Common anti-cancer drugs have recently been observed to induce the adoption of…

种群与进化 · 定量生物学 2025-07-04 Einar Bjarki Gunnarsson , Benedikt Vilji Magnússon , Jasmine Foo

Automated segmentation of Pancreatic Ductal Adenocarcinoma (PDAC) from MRI is critical for clinical workflows but is hindered by poor tumor-tissue contrast and a scarcity of annotated data. This paper details our submission to the PANTHER…

计算机视觉与模式识别 · 计算机科学 2025-09-01 Omer Faruk Durugol , Maximilian Rokuss , Yannick Kirchhoff , Klaus H. Maier-Hein