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Randomized Controlled Trials (RCTs) are often considered the gold standard for estimating causal effect, but they may lack external validity when the population eligible to the RCT is substantially different from the target population.…

统计方法学 · 统计学 2023-01-11 Bénédicte Colnet , Julie Josse , Erwan Scornet , Gaël Varoquaux

The ability to generalize experimental results from randomized control trials (RCTs) across locations is crucial for informing policy decisions in targeted regions. Such generalization is often hindered by the lack of identifiability due to…

计量经济学 · 经济学 2021-12-10 Xinkun Nie , Guido Imbens , Stefan Wager

In some causal inference scenarios, the treatment variable is measured inaccurately, for instance in epidemiology or econometrics. Failure to correct for the effect of this measurement error can lead to biased causal effect estimates.…

机器学习 · 计算机科学 2024-09-13 Antti Pöllänen , Pekka Marttinen

The case$^2$ study, also referred to as the case-case study design, is a valuable approach for conducting inference for treatment effects. Unlike traditional case-control studies, the case$^2$ design compares treatment in two types of cases…

统计方法学 · 统计学 2025-03-03 Kan Chen , Ting Ye , Dylan S. Small

Causal inference from observational data can be viewed as a missing data problem arising from a hypothetical population-scale randomized trial matched to the observational study. This links a target trial protocol with a corresponding…

统计方法学 · 统计学 2022-07-27 Andrew Yiu , Edwin Fong , Stephen Walker , Chris Holmes

In observational studies, the identification of causal estimands depends on the no unmeasured confounding (NUC) assumption. As this assumption is not testable from observed data, sensitivity analysis plays an important role in observational…

统计方法学 · 统计学 2023-09-28 Md Abdul Basit , Mahbub A. H. M. Latif , Abdus S Wahed

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

In designed experiments and surveys, known laws or design feat ures provide checks on the most relevant aspects of a model and identify the target parameters. In contrast, in most observational studies in the health and social sciences, the…

统计方法学 · 统计学 2010-01-18 Sander Greenland

Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target population in which experimentation may not be possible but covariate information can be…

统计方法学 · 统计学 2022-05-03 Jon A. Steingrimsson , David H. Barker , Ruofan Bie , Issa J. Dahabreh

In the absence of a randomized experiment, a key assumption for drawing causal inference about treatment effects is the ignorable treatment assignment. Violations of the ignorability assumption may lead to biased treatment effect estimates.…

统计方法学 · 统计学 2021-08-17 Liangyuan Hu , Jungang Zou , Chenyang Gu , Jiayi Ji , Michael Lopez , Minal Kale

Transportability provides a principled framework to address the problem of applying study results to new populations. Here, we consider the problem of selecting variables to include in transport estimators. We provide a brief overview of…

统计方法学 · 统计学 2019-12-11 Megha L. Mehrotra , M. Maria Glymour , Elvin Geng , Daniel Westreich , David V. Glidden

A randomized trial and an analysis of observational data designed to emulate the trial sample observations separately, but have the same eligibility criteria, collect information on some shared baseline covariates, and compare the effects…

统计方法学 · 统计学 2022-03-29 Issa J. Dahabreh , Jon A. Steingrimsson , James M. Robins , Miguel A. Hernán

Recent methods to improve generalizations from nonrandom samples typically invoke assumptions such as the strong ignorability of sample selection that are often controversial in practice to derive point estimates. Rather than focus on the…

应用统计 · 统计学 2017-01-06 Wendy Chan

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal…

统计方法学 · 统计学 2025-08-06 Wei Li , Jiapeng Liu , Peng Ding , Zhi Geng

The sensitivities revealed by a sensitivity analysis of a probabilistic network typically depend on the entered evidence. For a real-life network therefore, the analysis is performed a number of times, with different evidence. Although…

人工智能 · 计算机科学 2012-07-19 Silja Renooij , Linda C. van der Gaag

Difference-in-differences (DiD) is one of the most popular approaches for empirical research in economics, political science, and beyond. Identification in these models is based on the conditional parallel trends assumption: In the absence…

计量经济学 · 经济学 2025-10-13 Philipp Bach , Sven Klaassen , Jannis Kueck , Mara Mattes , Martin Spindler

Methods of transfer learning try to combine knowledge from several related tasks (or domains) to improve performance on a test task. Inspired by causal methodology, we relax the usual covariate shift assumption and assume that it holds true…

机器学习 · 统计学 2018-09-25 Mateo Rojas-Carulla , Bernhard Schölkopf , Richard Turner , Jonas Peters

Inferring the causal effect of a non-randomly assigned exposure on an outcome requires adjusting for common causes of the exposure and outcome to avoid biased conclusions. Notwithstanding the efforts investigators routinely make to measure…

统计方法学 · 统计学 2021-02-04 Wen Wei Loh , Stijn Vansteelandt

In observational studies, identification of ATEs is generally achieved by assuming that the correct set of confounders has been measured and properly included in the relevant models. Because this assumption is both strong and untestable, a…

统计方法学 · 统计学 2020-12-18 Matteo Bonvini , Edward H Kennedy

Sensitivity analysis is popular in dealing with missing data problems particularly for non-ignorable missingness. It analyses how sensitively the conclusions may depend on assumptions about missing data e.g. missing data mechanism (MDM). We…

统计方法学 · 统计学 2015-01-26 Peng Yin , Jian Qing Shi