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Several organelles in eukaryotic cells, including mitochondria and the endoplasmic reticulum, form interconnected tubule networks extending throughout the cell. These tubular networks host many biochemical pathways that rely on proteins…

The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular…

Network science investigates the architecture of complex systems to understand their functional and dynamical properties. Structural patterns such as communities shape diffusive processes on networks. However, these results hold under the…

物理与社会 · 物理学 2015-06-26 Jean-Charles Delvenne , Renaud Lambiotte , Luis E. C. Rocha

Quantifying how spatial disorder affects the movement of a diffusing particle or agent is fundamental to target search studies. When diffusion occurs on a network, that is on a highly disordered environment, we lack the mathematical tools…

统计力学 · 物理学 2025-08-15 Daniel Marris , Chittaranjan Hens , Subrata Ghosh , Luca Giuggioli

Novel experimental techniques reveal the simultaneous activity of larger and larger numbers of neurons. As a result there is increasing interest in the structure of cooperative -- or correlated -- activity in neural populations, and in the…

神经元与认知 · 定量生物学 2015-05-30 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

A heterogeneous continuous time random walk is an analytical formalism for studying and modeling diffusion processes in heterogeneous structures on microscopic and macroscopic scales. In this paper we study both analytically and numerically…

统计力学 · 物理学 2019-11-05 Liubov Tupikina , Denis S. Grebenkov

We present a novel framework for understanding node target search in systems organized as hierarchical networks-within-networks. Our work generalizes traditional search models on complex networks, where the mean-first passage time is…

生物物理 · 物理学 2024-11-06 Lucas Hedström , Seong-Gyu Yang , Ludvig Lizana

In eukaryotic cells, mitochondria form networks that range from highly fused interconnected structures to fragmented populations of individual organelles that undergo transient interactions. These structures can be described as temporal…

生物物理 · 物理学 2026-02-24 Keaton B. Holt , Camryn Zurita , Lizzy Teryoshin , Samantha C. Lewis , Elena F. Koslover

In a recurrent setting, conventional approaches to neural architecture search find and fix a general model for all data samples and time steps. We propose a novel algorithm that can dynamically search for the structure of cells in a…

机器学习 · 计算机科学 2019-05-28 Xin Qian , Matthew Kennedy , Diego Klabjan

Network science has emerged as a powerful tool through which we can study the higher-order architectural properties of the world around us. How human learners exploit this information remains an essential question. Here, we focus on the…

神经元与认知 · 定量生物学 2017-02-02 Elisabeth A. Karuza , Ari E. Kahn , Sharon L. Thompson-Schill , Danielle S. Bassett

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

分子网络 · 定量生物学 2007-05-23 Kanchan Thadani , Ashutosh

The brain can be considered as a system that dynamically optimizes the structure of anatomical connections based on the efficiency requirements of functional connectivity. To illustrate the power of this principle in organizing the…

神经元与认知 · 定量生物学 2024-02-07 Carlos Calvo Tapia , Valeriy A. Makarov Slizneva , Cees van Leeuwen

We use a simple dynamical model and explore coherent dynamics of wavepackets in complex networks of optical fibers. We start from a symmetric lattice and through the application of a Monte-Carlo criterion we introduce structural disorder…

光学 · 物理学 2014-09-30 F. Perakis , M. Mattheakis , G. P. Tsironis

Recent decades have seen the discovery of numerous complex materials. At the root of the complexity underlying many of these materials lies a large number of possible contending atomic- and larger-scale configurations and the intricate…

材料科学 · 物理学 2023-01-30 P. Ronhovde , S. Chakrabarty , M. Sahu , K. K. Sahu , K. F. Kelton , N. Mauro , Z. Nussinov

To better understand the temporal characteristics and the lifetime of fluctuations in stochastic processes in networks, we investigated diffusive persistence in various graphs. Global diffusive persistence is defined as the fraction of…

Intracellular processes often rely on the timely encounter of mobile reaction partners, including intermittently motor-driven organelles. The underlying cytoskeletal network presents a complex landscape that both directs particle movement…

生物物理 · 物理学 2025-12-17 Lizzy Teryoshin , Mario Hidalgo-Soria , Elena F. Koslover

Routing information through networks is a universal phenomenon in both natural and manmade complex systems. When each node has full knowledge of the global network connectivity, finding short communication paths is merely a matter of…

物理与社会 · 物理学 2009-05-20 Marian Boguna , Dmitri Krioukov , kc claffy

We develop a framework to track the structure of temporal networks with a signal processing approach. The method is based on the duality between networks and signals using a multidimensional scaling technique. This enables a study of the…

社会与信息网络 · 计算机科学 2015-05-13 Ronan Hamon , Pierre Borgnat , Patrick Flandrin , Céline Robardet

Experimentally monitoring the kinematics of branching network growth is a tricky task, given the complexity of the structures generated in three dimensions. One option is to drive the network in such a way as to obtain two-dimensional…

生物物理 · 物理学 2024-11-26 Thibault Chassereau , Florence Chapeland-Leclerc , Eric Herbert

Many real-world systems can be modeled as interconnected multilayer networks, namely a set of networks interacting with each other. Here we present a perturbative approach to study the properties of a general class of interconnected…

物理与社会 · 物理学 2018-07-10 Giacomo Rapisardi , Alex Arenas , Guido Caldarelli , Giulio Cimini
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