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Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

This study introduces a new framework for the artificial intelligence-assisted characterization of Gram-stained whole-slide images (WSIs). As a test for the diagnosis of bloodstream infections, Gram stains provide critical early data to…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Jack McMahon , Naofumi Tomita , Elizabeth S. Tatishev , Adrienne A. Workman , Cristina R Costales , Niaz Banaei , Isabella W. Martin , Saeed Hassanpour

Whole-Slide Images (WSIs) have revolutionized medical analysis by presenting high-resolution images of the whole tissue slide. Despite avoiding the physical storage of the slides, WSIs require considerable data volume, which makes the…

图像与视频处理 · 电气工程与系统科学 2025-03-25 Yu Mao , Jun Wang , Nan Guan , Chun Jason Xue

Assessing microsatellite stability status of a patient's colorectal cancer is crucial in personalizing treatment regime. Recently, convolutional-neural-networks (CNN) combined with transfer-learning approaches were proposed to circumvent…

计算机视觉与模式识别 · 计算机科学 2022-08-23 Daniel Shats , Hadar Hezi , Guy Shani , Yosef E. Maruvka , Moti Freiman

To obtain microscope images at multiple focal planes, the distance between the objective and sample can be mechanically adjusted. Images are acquired sequentially at each axial distance. Digital refocusing with a light-emitting diode (LED)…

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Whole slide image (WSI) classification is a crucial problem for cancer diagnostics in clinics and hospitals. A WSI, acquired at gigapixel size, is commonly tiled into patches and processed by multiple-instance learning (MIL) models.…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Doanh C. Bui , Jin Tae Kwak

Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

计算机视觉与模式识别 · 计算机科学 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

计算机视觉与模式识别 · 计算机科学 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Objective: This article presents an automatic image processing framework to extract quantitative high-level information describing the micro-environment of glomeruli in consecutive whole slide images (WSIs) processed with different staining…

计算机视觉与模式识别 · 计算机科学 2021-05-04 Odyssee Merveille , Thomas Lampert , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…

计算工程、金融与科学 · 计算机科学 2023-09-14 Yuandou Wang , Neel Kanwal , Kjersti Engan , Chunming Rong , Zhiming Zhao

Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Sparse sampling schemes have the potential to dramatically reduce image acquisition time while simultaneously reducing radiation damage to samples. However, for a sparse sampling scheme to be useful it is important that we are able to…

计算机视觉与模式识别 · 计算机科学 2017-03-16 G. M. Dilshan P. Godaliyadda , Dong Hye Ye , Michael D. Uchic , Michael A. Groeber , Gregery T. Buzzard , Charles A. Bouman

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

图像与视频处理 · 电气工程与系统科学 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

图像与视频处理 · 电气工程与系统科学 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori