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Neural growth is the process of growing a small neural network to a large network and has been utilized to accelerate the training of deep neural networks. One crucial aspect of neural growth is determining the optimal growth timing.…

机器学习 · 计算机科学 2024-01-09 Haihang Wu , Wei Wang , Tamasha Malepathirana , Damith Senanayake , Denny Oetomo , Saman Halgamuge

Many mathematical models of synaptic plasticity have been proposed to explain the diversity of plasticity phenomena observed in biological organisms. These models range from simple interpretations of Hebb's postulate, which suggests that…

神经元与认知 · 定量生物学 2025-08-05 Danil Tyulmankov

Neuroimaging measures of the brain's white matter connections can enable the prediction of non-imaging phenotypes, such as demographic and cognitive measures. Existing works have investigated traditional microstructure and connectivity…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Wan Liu , Yuqian Chen , Chuyang Ye , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

This paper continues the research that considers a new cognitive model based strongly on the human brain. In particular, it considers the neural binding structure of an earlier paper. It also describes some new methods in the areas of image…

人工智能 · 计算机科学 2018-12-11 Kieran Greer

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

图像与视频处理 · 电气工程与系统科学 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

生物物理 · 物理学 2023-08-25 Mengyang Gu , Xinyi Fang , Yimin Luo

We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a…

计算机视觉与模式识别 · 计算机科学 2017-11-27 Alexandre Bône , Maxime Louis , Alexandre Routier , Jorge Samper , Michael Bacci , Benjamin Charlier , Olivier Colliot , Stanley Durrleman

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

图像与视频处理 · 电气工程与系统科学 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

Morphogenetic dynamics of tissue sheets require coordinated cell shape changes regulated by global patterning of mechanical forces. Inspired by such biological phenomena, we propose a minimal mechanochemical model based on the notion that…

软凝聚态物质 · 物理学 2021-01-01 Andrei Zakharov , Kinjal Dasbiswas

In spite of the large amount of existing neural models in the literature, there is a lack of a systematic review of the possible effect of choosing different initial conditions on the dynamic evolution of neural systems. In this short…

神经元与认知 · 定量生物学 2016-05-24 Pedro A. Valdes-Hernandez , Thomas Knoesche

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…

Artificial and biological systems may evolve similar computational solutions despite fundamental differences in architecture and learning mechanisms -- a form of convergent evolution. We demonstrate this phenomenon through large-scale…

神经元与认知 · 定量生物学 2025-07-04 Guobin Shen , Dongcheng Zhao , Yiting Dong , Qian Zhang , Yi Zeng

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Understanding how the brain learns can be advanced by investigating biologically plausible learning rules -- those that obey known biological constraints, such as locality, to serve as valid brain learning models. Yet, many studies overlook…

神经与进化计算 · 计算机科学 2025-01-13 Weixuan Liu , Xinyue Zhang , Yuhan Helena Liu

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.…

定量方法 · 定量生物学 2007-05-23 M. S. Barbosa , L. da F. Costa , E. S. Bernardes , G. Ramakers , J. van Pelt

Causal reasoning provides a language to ask important interventional and counterfactual questions beyond purely statistical association. In medical imaging, for example, we may want to study the causal effect of genetic, environmental, or…

计算机视觉与模式识别 · 计算机科学 2022-08-24 Rajat Rasal , Daniel C. Castro , Nick Pawlowski , Ben Glocker

Human physical reasoning relies on internal "body" representations - coarse, volumetric approximations that capture an object's extent and support intuitive predictions about motion and physics. While psychophysical evidence suggests humans…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Andrey Gizdov , Andrea Procopio , Yichen Li , Daniel Harari , Tomer Ullman

A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…

生物物理 · 物理学 2018-12-26 T. A. Engstrom , Teng Zhang , A. K. Lawton , A. L. Joyner , J. M. Schwarz

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

图像与视频处理 · 电气工程与系统科学 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap