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Nutrient gradients and limitations play a pivotal role in the life of all microbes, both in their natural habitat as well as in artificial, microfluidic systems. Spatial concentration gradients of nutrients in densely packed cell…

The spatiotemporal oscillations of the Min proteins in the bacterium Escherichia coli play an important role in cell division. A number of different models have been proposed to explain the dynamics from the underlying biochemistry. Here,…

亚细胞过程 · 定量生物学 2013-05-29 Peter Borowski , Eric N. Cytrynbaum

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

细胞行为 · 定量生物学 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Bacterial biofilms mechanically behave as viscoelastic media consisting of micron-sized bacteria crosslinked to a selfproduced network of extracellular polymeric substances (EPS) embedded in water. Structural principles for numerical…

This chapter gives a synopsis of recent approaches to model and analyse the evolution of microbial populations under selection. The first part reviews two population genetic models of Lenski's long-term evolution experiment with Escherichia…

种群与进化 · 定量生物学 2021-06-30 Ellen Baake , Anton Wakolbinger

Peritrichous bacteria such as Escherichia coli swim in viscous fluids by forming a helical bundle of flagellar filaments. The filaments are spatially distributed around the cell body to which they are connected via a flexible hook. To…

生物物理 · 物理学 2019-06-19 Kenta Ishimoto , Eric Lauga

Recent work suggests that cross-feeding -- the secretion and consumption of metabolic biproducts by microbes -- is essential for understanding microbial ecology. Yet how cross-feeding and competition combine to give rise to ecosystem-level…

种群与进化 · 定量生物学 2021-10-12 Pankaj Mehta , Robert Marsland

One of the major research questions regarding human microbiome studies is the feasibility of designing interventions that modulate the composition of the microbiome to promote health and cure disease. This requires extensive understanding…

统计方法学 · 统计学 2021-11-18 Matthew D. Koslovsky , Kristi L. Hoffman , Carrie R. Daniel , Marina Vannucci

Microorganisms are ubiquitous in nature and technology. They inhabit diverse environments ranging from small river tributaries and lakes to oceans, as well as wastewater treatment plants and food manufacturing. In many of these…

Growth in bacterial populations generally depends on the environment (availability and quality of nutrients, presence of a toxic inhibitor, product inhibition..). Here, we build a model to describe the action of a bacteriostatic antibiotic,…

生物物理 · 物理学 2025-06-25 Barnabe Ledoux , David Lacoste

Dictyostelium discoideum is an ideal organism to test the pathogenicity of Pseudomonas aeruginosa, since its eukaryote nature allows for comparisons to be made to human health. Additionally, D. discoideum naturally feeds on bacteria and has…

细胞行为 · 定量生物学 2018-06-28 Asher Parvu , Katherine Ortiz

Using very precise (up to 0.05%) measurements of the growth parameters for bacteria E. coli grown on minimal media, we aimed to determine the lowest deuterium concentration at which the adverse effects that are prominent at higher…

定量方法 · 定量生物学 2015-01-06 Xueshu Xie , Roman A. Zubarev

Most of our understanding of bacterial chemotaxis comes from studies of Escherichia coli. However, recent evidence suggests significant departures from the E. coli paradigm in other bacterial species. This variation may stem from different…

细胞行为 · 定量生物学 2015-03-27 Martin Godány , Bhavin S. Khatri , Richard A. Goldstein

We investigate the structure of gluten polymer-like gels in a binary mixture of water/ethanol, $50/50$ v/v, a good solvent for gluten proteins. Gluten comprises two main families of proteins, monomeric gliadins and polymer glutenins. In the…

A wide spectrum of Peritrichous bacteria undergo considerable physiological changes when they are inoculated onto nutrition-rich surfaces and exhibit a rapid and collective migration denoted as swarming. Thereby, the length of such swarmer…

生物物理 · 物理学 2016-10-25 Thomas Eisenstecken , Jinglei Hu , Roland G. Winkler

Motivated by the existence of remarkably ordered cluster arrays of bacteria colonies growing in Petri dishes and related problems, we study the spontaneous emergence of clustering and patterns in a simple nonequilibrium system: the…

统计力学 · 物理学 2009-11-13 Francisco Ramos , Cristobal Lopez , E. Hernandez-Garcia , Miguel A. Munoz

The migration of helical particles in viscous shear flows plays a crucial role in chiral particle sorting. Attaching a non-chiral head to a helical particle leads to a rheotactic torque inducing particle reorientation. This phenomenon is…

软凝聚态物质 · 物理学 2023-10-18 Andreas Zöttl , Francesca Tesser , Daiki Matsunaga , Justine Laurent , Olivia Du Roure , Anke Lindner

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

流体动力学 · 物理学 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

分子网络 · 定量生物学 2019-08-19 Thierry Emonet , Philippe Cluzel

Present study is dedicated to the problem of electrochemical analysis of multicomponent mixtures such as milk. A combination of cyclic voltammetry facilities and machine learning technique made it possible to create a pattern recognition…