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Ultrafast Electron Microscopy (UEM) has been demonstrated to be an effective table-top technique for imaging the temporally-evolving dynamics of matter with subparticle spatial resolution on the time scale of atomic motion. However, imaging…

光学 · 物理学 2017-08-02 M. Th. Hassan , J. S. Baskin , B. Liao , A. H. Zewail

Despite the widespread use of Scanning Transmission Electron Microscopy (STEM) for observing the structure of materials at the atomic scale, a detailed understanding of some relevant electron beam damage mechanisms is limited. Recent…

Instruments to visualize transient structural changes of inhomogeneous materials on the nanometer scale with atomic spatial and temporal resolution are demanded to advance materials science, bioscience, and fusion sciences. One such…

加速器物理 · 物理学 2017-03-20 X. Shen , R. K. Li , U. Lundström , T. J. Lane , A. H. Reid , S. P. Weathersby , X. J. Wang

Transmission electron microscopes use electrons with wavelengths of a few picometers, potentially capable of imaging individual atoms in solids at a resolution ultimately set by the intrinsic size of an atom. Unfortunately, due to…

Numerous physical phase plates (PP) for phase-contrast enhancement in transmission electron microscopy (TEM) have been proposed and studied with the hole-free or Volta PP having a high impact and interest in recent years. This study is…

仪器与探测器 · 物理学 2021-05-25 Simon Hettler , Raul Arenal

Weak-signal detection and single-particle selection from low-contrast micrographs of frozen hydrated biomolecules by cryo-electron microscopy (cryo-EM) presents a practical challenge. Cryo-EM image contrast degrades as the size of…

定量方法 · 定量生物学 2019-04-16 Youdong Mao , Luis R. Castillo-Menendez , Joseph Sodroski

Microscopy has been key to tremendous advances in science, technology, and medicine, revealing structure and dynamics across time and length scales. However, combining high spatial and temporal resolution in a non-invasive, label-free…

Electrical capacitance tomography (ECT) is a nonoptical imaging technique in which a map of the interior permittivity of a volume is estimated by making capacitance measurements at its boundary and solving an inverse problem. While previous…

计算机视觉与模式识别 · 计算机科学 2023-12-05 Manar Abdelatty , Joseph Incandela , Kangping Hu , Joseph W. Larkin , Sherief Reda , Jacob K. Rosenstein

The design of multi-channel gas electron multiplier (MGEM) with metallic electrodes is proposed, produced and tested. The electrodes of MGEM are produced from the brass plates with thickness of 1 mm, round openings of 1 mm in diameter and…

仪器与探测器 · 物理学 2010-06-17 B. M. Ovchinnikov , V. V. Parusov , Yu. B. Ovchinnikov

Contrast transfer mechanisms for electron scattering have been extensively studied in transmission electron microscopy. Here we revisit H. Rose's generalized contrast formalism from scattering theory to understand where information is…

光学 · 物理学 2025-10-28 Desheng Ma , Guanxing Li , David A Muller , Steven E Zeltmann

Single particle electron cryomicroscopy (cryo-EM) allows for structures of proteins and protein complexes to be determined from images of non-crystalline specimens. Cryo-EM data analysis requires electron microscope images of randomly…

仪器与探测器 · 物理学 2015-11-23 Jianhua Zhao , Marcus A. Brubaker , Samir Benlekbir , John L. Rubinstein

Electron cryo-tomography (cryo-ET) enables 3D imaging of complex, radiation-sensitive structures with molecular detail. However, image contrast from the interference of scattered electrons is nonlinear with atomic density and multiple…

The multi-Photomultiplier Tube (mPMT) photosensors will be used in the Water Cherenkov Test Experiment (WCTE) to efficiently detect the photons produced in the whole detector. One of the aims behind the development of WCTE is to test the…

For many complex materials systems, low-energy electron microscopy (LEEM) offers detailed insights into morphology and crystallography by naturally combining real-space and reciprocal-space information. Its unique strength, however, is that…

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

图像与视频处理 · 电气工程与系统科学 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

Ultra-fast transmission electron microscopy (UTEM) combines sub-picosecond time-resolution with the versatility of TEM spectroscopies. It allows one to study the dynamics of materials properties combining complementary techniques. However,…

材料科学 · 物理学 2021-08-25 S. Meuret , L. H. G. Tizei , F. Houdellier , S. Weber , Y. Auad , M. Tencé , H. -C. Chang , M. Kociak , A. Arbouet

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

仪器与探测器 · 物理学 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

We report on a new technique of a Multi-Cathode Counter (MCC) developed to search for hidden photon (HP) cold dark matter (CDM) with a mass from 5 to 500 eV. The method is suggested in the assumption that HP-photon mixing causes emission of…

仪器与探测器 · 物理学 2016-06-20 A. V. Kopylov , I. V. Orekhov , V. V. Petukhov

We introduce a new image contrast mechanism for scanning transmission electron microscopy (STEM) that derives from the local symmetry within the specimen. For a given position of the electron probe on the specimen, the image intensity is…

材料科学 · 物理学 2020-12-30 Matus Krajnak , Joanne Etheridge

The development of four-dimensional (4D) scanning transmission electron microscopy (STEM) using fast detectors has opened-up new avenues for addressing some of long-standing challenges in electron imaging. One of these challenges is how to…

材料科学 · 物理学 2021-01-19 Yu-Tsun Shao , Renliang Yuan , Haw-Wen Hsiao , Qun Yang , Yang Hu , Jian-Min Zuo