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In the context of a binary classification problem, the optimal linear combination of continuous predictors can be estimated by maximizing an empirical estimate of the area under the receiver operating characteristic (ROC) curve (AUC). For…

In medical diagnostics, leveraging multiple biomarkers can significantly improve classification accuracy compared to using a single biomarker. While existing methods based on exponential tilting or density ratio models have shown promise,…

统计方法学 · 统计学 2026-01-08 Fangyong Zheng , Pengfei Li , Tao Yu

In medical research, it is common to collect information of multiple continuous biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these biomarkers into one single score is a popular practice to integrate…

应用统计 · 统计学 2015-07-08 Tu Xu , Yixin Fang , Alan Rong , Junhui Wang

In clinical practice, multiple biomarkers are used for disease diagnosis, but their individual accuracies are often suboptimal, with only a few proving directly relevant. Effectively selecting and combining biomarkers can significantly…

统计方法学 · 统计学 2025-09-03 Ao Sun , Zhanwang Deng , Jiahui Zhao , Hang Li , Xiao-Hua Zhou

The Helstrom measurement (HM) is known to be the optimal strategy for distinguishing non-orthogonal quantum states with minimum error. Previously, a binary classifier based on classical simulation of the HM has been proposed. It was…

量子物理 · 物理学 2024-03-25 Wooseop Hwang , Daniel K. Park , Israel F. Araujo , Carsten Blank

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

计算机视觉与模式识别 · 计算机科学 2025-07-18 Zahid Ullah , Dragan Pamucar , Jihie Kim

Accurate brain tumor classification is crucial in medical imaging to ensure reliable diagnosis and effective treatment planning. This study introduces a novel double ensembling framework that synergistically combines pre-trained deep…

计算机视觉与模式识别 · 计算机科学 2025-06-17 Zahid Ullah , Jihie Kim

In this work we propose a Bayesian framework for fully automated image fusion and their joint segmentation. More specifically, we consider the case where we have observed images of the same object through different image processes or…

数据分析、统计与概率 · 物理学 2007-05-23 Olivier Feron , Ali Mohammad-Djafari

In clinical practice, multiple biomarkers are often measured on the same subject for disease diagnosis, and combining them can improve diagnostic accuracy. Existing studies typically combine multiple biomarkers by maximizing the Area Under…

统计方法学 · 统计学 2025-02-25 Ao Sun , Yanting Li , Xiao-Hua Zhou

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Objective: The primary goal of this study was to systematically examine the impact of commonly used imbalance handling methods (IHMs) on predictive performance in biomedical binary classification, considering the interplay between model…

机器学习 · 计算机科学 2026-05-15 Jiandong Chen , Lingjie Su , Le Peng , Yash Travadi , Rui Zhang , Ju Sun

In this paper, we consider the problem of automatic modulation classification with multiple sensors in the presence of unknown time offset, phase offset and received signal amplitude. We develop a novel hybrid maximum likelihood (HML)…

其他计算机科学 · 计算机科学 2015-02-05 O. Ozdemir , T. Wimalajeewa , B. Dulek , P. K. Varshney , W. Su

Computational studies that use block-structured adaptive mesh refinement (AMR) approaches suffer from unnecessarily high mesh resolution in regions adjacent to important solution features. This deficiency limits the performance of AMR…

计算物理 · 物理学 2022-03-02 Brandon Gusto , Tomasz Plewa

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

In this paper a hybrid feature selection method is proposed which takes advantages of wrapper subset evaluation with a lower cost and improves the performance of a group of classifiers. The method uses combination of sample domain filtering…

机器学习 · 计算机科学 2014-03-12 Mehdi Naseriparsa , Amir-Masoud Bidgoli , Touraj Varaee

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

图像与视频处理 · 电气工程与系统科学 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

Many practical applications of AI in medicine consist of semi-supervised discovery: The investigator aims to identify features of interest at a resolution more fine-grained than that of the available human labels. This is often the scenario…

计算与语言 · 计算机科学 2020-04-08 Allen Schmaltz , Andrew Beam

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

机器学习 · 计算机科学 2025-11-21 Chongmin Lee , Jihie Kim

In this work we propose a Bayesian framework for data fusion of multivariate signals which arises in imaging systems. More specifically, we consider the case where we have observed two images of the same object through two different imaging…

数据分析、统计与概率 · 物理学 2007-05-23 Olivier Feron , Ali Mohammad-Djafari
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