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Federated learning enables different parties to collaboratively build a global model under the orchestration of a server while keeping the training data on clients' devices. However, performance is affected when clients have heterogeneous…

Clustering cancer patients into subgroups and identifying cancer subtypes is an important task in cancer genomics. Clustering based on comprehensive multi-omic molecular profiling can often achieve better results than those using a single…

基因组学 · 定量生物学 2017-08-25 Tianle Ma , Aidong Zhang

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

The demand for efficient machine learning (ML) accelerators is growing rapidly, driving the development of novel computing concepts such as resistive random access memory (RRAM)-based tiled computing-in-memory (CIM) architectures. CIM…

硬件体系结构 · 计算机科学 2024-01-18 Rebecca Pelke , Jose Cubero-Cascante , Nils Bosbach , Felix Staudigl , Rainer Leupers , Jan Moritz Joseph

We present a data-driven analysis of MOCK, $\Delta$-MOCK, and MOCLE. These are three closely related approaches that use multi-objective optimization for crisp clustering. More specifically, based on a collection of 12 datasets presenting…

机器学习 · 计算机科学 2021-10-26 Adriano Kultzak , Cristina Y. Morimoto , Aurora Pozo , Marcílio C. P. de Souto

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

计算机视觉与模式识别 · 计算机科学 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

In light of their capability to capture structural information while reducing computing complexity, anchor graph-based multi-view clustering (AGMC) methods have attracted considerable attention in large-scale clustering problems.…

机器学习 · 计算机科学 2025-09-19 Zhiyuan Xue , Ben Yang , Xuetao Zhang , Fei Wang , Zhiping Lin

Educators evaluate student knowledge using knowledge component (KC) models that map assessment questions to KCs. Still, designing KC models for large question banks remains an insurmountable challenge for instructors who need to analyze…

人工智能 · 计算机科学 2025-09-19 Yumou Wei , Paulo Carvalho , John Stamper

Principal component analysis (PCA), the most popular dimension-reduction technique, has been used to analyze high-dimensional data in many areas. It discovers the homogeneity within the data and creates a reduced feature space to capture as…

统计方法学 · 统计学 2026-03-24 Daning Bi , Le Chang , Yanrong Yang

Single-cell multi-view clustering enables the exploration of cellular heterogeneity within the same cell from different views. Despite the development of several multi-view clustering methods, two primary challenges persist. Firstly, most…

基因组学 · 定量生物学 2023-11-30 Dayu Hu , Zhibin Dong , Ke Liang , Jun Wang , Siwei Wang , Xinwang Liu

Spectral clustering is one of the most prominent clustering approaches. The distance-based similarity is the most widely used method for spectral clustering. However, people have already noticed that this is not suitable for multi-scale…

机器学习 · 计算机科学 2020-09-11 Hengrui Wang , Yubo Zhang , Mingzhi Chen , Tong Yang

This paper presents Orthogonal Subspace Clustering (OSC), an innovative method for high-dimensional data clustering. We first establish a theoretical theorem proving that high-dimensional data can be decomposed into orthogonal subspaces in…

机器学习 · 计算机科学 2026-03-17 Qing-Yuan Wen , Da-Qing Zhang

With the increasing number of samples, the manual clustering of COVID-19 and medical disease data samples becomes time-consuming and requires highly skilled labour. Recently, several algorithms have been used for clustering medical datasets…

神经与进化计算 · 计算机科学 2021-09-21 Bryar A. Hassan , Tarik A. Rashid , Hozan K. Hamarashid

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

计算机视觉与模式识别 · 计算机科学 2021-11-30 Simon Graham , Mostafa Jahanifar , Quoc Dang Vu , Giorgos Hadjigeorghiou , Thomas Leech , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Independent Component Analysis (ICA) is an effective unsupervised tool to learn statistically independent representation. However, ICA is not only sensitive to whitening but also difficult to learn an over-complete basis. Consequently, ICA…

计算机视觉与模式识别 · 计算机科学 2013-04-10 Yanhui Xiao , Zhenfeng Zhu , Yao Zhao

The current medical standard for setting an oral cancer (OC) diagnosis is histological examination of a tissue sample from the oral cavity. This process is time consuming and more invasive than an alternative approach of acquiring a brush…

图像与视频处理 · 电气工程与系统科学 2022-02-07 Nadezhda Koriakina , Nataša Sladoje , Vladimir Bašić , Joakim Lindblad

The analysis of data streams has received considerable attention over the past few decades due to sensors, social media, etc. It aims to recognize patterns in an unordered, infinite, and evolving stream of observations. Clustering this type…

机器学习 · 计算机科学 2022-01-14 Mohammed Oualid Attaoui , Hanene Azzag , Mustapha Lebbah , Nabil Keskes

Early detection of cancers has been much explored due to its paramount importance in biomedical fields. Among different types of data used to answer this biological question, studies based on T cell receptors (TCRs) are under recent…

机器学习 · 统计学 2022-08-10 Younghoon Kim , Tao Wang , Danyi Xiong , Xinlei Wang , Seongoh Park

Clustering functional data in the presence of phase variation is challenging, as temporal misalignment can obscure intrinsic shape differences and degrade clustering performance. Most existing approaches treat registration and clustering as…

机器学习 · 统计学 2026-04-30 Xinyang Xiong , Siyuan jiang , Pengcheng Zeng

We address the problem of federated learning (FL) where users are distributed and partitioned into clusters. This setup captures settings where different groups of users have their own objectives (learning tasks) but by aggregating their…

机器学习 · 统计学 2021-06-10 Avishek Ghosh , Jichan Chung , Dong Yin , Kannan Ramchandran