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Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of…

Dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) is a widely used multi-phase technique routinely used in clinical practice. DCE and similar datasets of dynamic medical data tend to contain redundant information on the…

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

神经元与认知 · 定量生物学 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Dispersion is a common phenomenon in optics due to the frequency dependence of the refractive index in polychromatic light. This issue, if left untreated in optical coherence tomography (OCT) imaging, leads to signal broadening of the…

图像与视频处理 · 电气工程与系统科学 2022-01-03 Shangbang Luo , Guy Holland , Eric Mikula , Samantha Bradford , Reza Khazaeinezhad , James V Jester , Tibor Juhasz

Brain cell structure and function reflect neurodevelopment, plasticity and ageing, and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to non-invasively…

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

We review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse-graining over an increasing diffusion length scale. From this perspective, we view research on…

生物物理 · 物理学 2018-04-20 Dmitry S. Novikov , Els Fieremans , Sune N. Jespersen , Valerij G. Kiselev

Treatment planning, which is a critical component of the radiotherapy workflow, is typically carried out by a medical physicist in a time-consuming trial-and-error manner. Previous studies have proposed knowledge-based or…

图像与视频处理 · 电气工程与系统科学 2024-03-29 Yiwen Zhang , Chuanpu Li , Liming Zhong , Zeli Chen , Wei Yang , Xuetao Wang

Diffusion-weighted imaging (DWI) is a type of Magnetic Resonance Imaging (MRI) technique sensitised to the diffusivity of water molecules, offering the capability to inspect tissue microstructures and is the only in-vivo method to…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Sheng Chen , Zihao Tang , Mariano Cabezas , Xinyi Wang , Arkiev D'Souza , Michael Barnett , Fernando Calamante , Weidong Cai , Chenyu Wang

The human brain constitutes 2% of the total body mass, but consumes 20% of the oxygen. The rate of the brain's oxygen utilization can be determined from the knowledge of cerebral blood flow and oxygen extraction fraction (OEF). Therefore,…

医学物理 · 物理学 2022-02-04 Dengrong Jiang , Hanzhang Lu

Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2-3 percent. Recently, brain activity in the resting state is gathering attention as a new means of exploring altered functional connectivity…

Traveling-wave optical coherence elastography (OCE) is a promising technique to measure the stiffness of biological tissues. While OCE has been applied to relatively homogeneous samples, tissues with significantly varying elasticity through…

医学物理 · 物理学 2022-01-31 Xu Feng , Guo-Yang Li , Antoine Ramier , Amira M. Eltony , Seok-Hyun Yun

We analyze the frequency dependence of the dispersion measure (DM), the column density of free electrons to a pulsar, caused by multipath scattering from small scale electron-density fluctuations. The DM is slightly different along each…

天体物理仪器与方法 · 物理学 2016-01-21 J. M. Cordes , R. M. Shannon , D. R. Stinebring

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive way of imaging white matter tracts in the human brain. DW-MRIs are usually acquired using echo-planar imaging (EPI) with high gradient fields, which could introduce…

图像与视频处理 · 电气工程与系统科学 2023-04-04 Zhangxing Bian , Muhan Shao , Aaron Carass , Jerry L. Prince

Apparent diffusion coefficient (ADC) is a measure of the magnitude of diffusion of water molecules within tissues. We argue that ADC value contains information of both diffusion and T2 relaxation. In this letter, we list literature evidence…

医学物理 · 物理学 2023-06-21 Yi Xiang J. Wang

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

图像与视频处理 · 电气工程与系统科学 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

图像与视频处理 · 电气工程与系统科学 2025-01-07 Ashiqur Rahman , Muhammad E. H. Chowdhury , Md Sharjis Ibne Wadud , Rusab Sarmun , Adam Mushtak , Sohaib Bassam Zoghoul , Israa Al-Hashimi

Diffusion pore imaging is an extension of diffusion-weighted nuclear magnetic resonance imaging enabling the direct measurement of the shape of arbitrarily formed, closed pores by probing diffusion restrictions using the motion of…

Purpose: Apparent diffusion coefficient (ADC) maps derived from diffusion weighted (DWI) MRI provides functional measurements about the water molecules in tissues. However, DWI is time consuming and very susceptible to image artifacts,…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Zach Eidex , Mojtaba Safari , Jacob Wynne , Richard L. J. Qiu , Tonghe Wang , David Viar Hernandez , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang