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Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

计算机视觉与模式识别 · 计算机科学 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Scientists construct connectomes, comprehensive descriptions of neuronal connections across a brain, in order to better understand and model brain function. Interactive visualizations of these pathways would enable exploratory analysis of…

神经元与认知 · 定量生物学 2022-05-06 Seth Daetwiler , Angus Read , Jessica Stillwell , Kameron Decker Harris

Reaching a global view of brain organization requires assembling evidence on widely different mental processes and mechanisms. The variety of human neuroscience concepts and terminology poses a fundamental challenge to relating brain…

Graph databases have been the subject of significant research and development. Problems such as modularity, centrality, alignment, and clustering have been formalized and solved in various application contexts. In this paper, we focus on…

社会与信息网络 · 计算机科学 2019-08-09 Vikram Ravindra , Huda Nassar , David F. Gleich , Ananth Grama

How an individual's unique brain connectivity determines that individual's cognition, behavior, and risk for pathology is a fundamental question in basic and clinical neuroscience. In seeking answers, many have turned to machine learning,…

神经元与认知 · 定量生物学 2023-12-08 Maxwell A. Bertolero , Dustin Moraczewski , Adam Thomas , Danielle S. Bassett

Brain imaging data mapping onto human connectome networks enables the investigation of global brain dynamics, where the brain hubs play an essential role in transferring activity between different brain parts. At this scale, the…

斑图形成与孤子 · 物理学 2025-07-11 Bosiljka Tadic , Marija Mitrovic Dankulov , Roderick Melnik

In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach. In this new context, it is important to know not only which brain areas are activated by a…

神经元与认知 · 定量生物学 2019-04-17 Jean Faber , Priscila C. Antoneli , Guillem Via , Noemi S. Araújo , Daniel J. L. L. Pinheiro , Esper Cavalheiro

In this study, we explore the fundamental principles behind the architecture of the human brain's structural connectome, from the perspective of spectral analysis of Laplacian and adjacency matrices. Building on the idea that the brain…

神经元与认知 · 定量生物学 2024-05-28 Anna Bobyleva , Alexander Gorsky , Sergei Nechaev , Olga Valba , Nikita Pospelov

As one of the most fundamental tasks in graph theory, subgraph matching is a crucial task in many fields, ranging from information retrieval, computer vision, biology, chemistry and natural language processing. Yet subgraph matching problem…

机器学习 · 计算机科学 2022-09-19 Zixun Lan , Limin Yu , Linglong Yuan , Zili Wu , Qiang Niu , Fei Ma

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Data-driven graph learning models a network by determining the strength of connections between its nodes. The data refers to a graph signal which associates a value with each graph node. Existing graph learning methods either use simplified…

机器学习 · 计算机科学 2020-11-05 Nafiseh Ghoroghchian , David M. Groppe , Roman Genov , Taufik A. Valiante , Stark C. Draper

Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural,…

神经元与认知 · 定量生物学 2016-09-13 Xindi Wang , Qixiang Lin , Mingrui Xia , Yong He

Memory is an important cognitive function for humans. How a brain with such a small power can complete such a complex memory function, the working mechanism behind this is undoubtedly fascinating. Engram theory views memory as the…

分布式、并行与集群计算 · 计算机科学 2023-07-13 Hui Wei , Weihua Miao , Fushun Li

Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…

社会与信息网络 · 计算机科学 2020-06-11 Tommaso Lanciano , Francesco Bonchi , Aristides Gionis

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

神经元与认知 · 定量生物学 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

We perform a massive evaluation of neural networks with architectures corresponding to random graphs of various types. We investigate various structural and numerical properties of the graphs in relation to neural network test accuracy. We…

机器学习 · 计算机科学 2020-12-03 Romuald A. Janik , Aleksandra Nowak

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

信号处理 · 电气工程与系统科学 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

fMRI is a non-invasive technique for investigating brain activity, offering high-resolution insights into neural processes. Understanding and decoding cognitive brain states from fMRI depends on how functional interactions are represented.…

神经元与认知 · 定量生物学 2026-02-23 Daniil Vlasenko , Vadim Ushakov , Alexey Zaikin , Denis Zakharov