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Brain connectomes offer detailed maps of neural connections within the brain. Recent studies have proposed novel connectome graph datasets and attempted to improve connectome classification by using graph deep learning. With recent advances…

机器学习 · 计算机科学 2025-03-21 Jose Lara-Rangel , Clare Heinbaugh

Connections of the living human brain, on a macroscopic scale, can be mapped by a diffusion MR imaging based workflow. Since the same anatomic regions can be corresponded between distinct brains, one can compare the presence or the absence…

神经元与认知 · 定量生物学 2016-02-16 Balázs Szalkai , Csaba Kerepesi , Bálint Varga , Vince Grolmusz

The average human brain volume of the males is larger than that of the females. Several MRI voxel-based morphometry studies show that the gray matter/white matter ratio is larger in females. Here we have analyzed the recent public release…

神经元与认知 · 定量生物学 2016-04-21 Balázs Szalkai , Vince Grolmusz

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Finding the common structural brain connectivity network for a given population is an open problem, crucial for current neuro-science. Recent evidence suggests there's a tightly connected network shared between humans. Obtaining this…

神经元与认知 · 定量生物学 2017-01-10 Nahuel Lascano , Guillermo Gallardo , Rachid Deriche , Dorian Mazauric , Demian Wassermann

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

神经元与认知 · 定量生物学 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

In brain connectomics, the cortical surface is parcellated into different regions of interest (ROIs) prior to statistical analysis. The brain connectome for each individual can then be represented as a graph, with the nodes corresponding to…

统计方法学 · 统计学 2020-10-07 Steven Winter , Zhengwu Zhang , David Dunson

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

统计方法学 · 统计学 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

This paper presents a comprehensive and quality collection of functional human brain network data for potential research in the intersection of neuroscience, machine learning, and graph analytics. Anatomical and functional MRI images have…

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

神经元与认知 · 定量生物学 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

定量方法 · 定量生物学 2016-02-03 Sean L. Simpson , Paul J. Laurienti

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

机器学习 · 计算机科学 2016-12-06 Colin J Brown , Ghassan Hamarneh

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

物理与社会 · 物理学 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

A recent publication provides the network graph for a neocortical microcircuit comprising 8 million connections between 31,000 neurons (H. Markram, et al., Reconstruction and simulation of neocortical microcircuitry, Cell, 163 (2015) no. 2,…

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

神经元与认知 · 定量生物学 2013-10-16 Marcus Kaiser

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

神经元与认知 · 定量生物学 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

机器学习 · 计算机科学 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang

Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

神经元与认知 · 定量生物学 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López