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The growing interest in developing smart diagnostic systems to help medical experts process extensive data for treating incurable diseases has been notable. In particular, the challenge of identifying thyroid cancer (TC) has seen progress…

机器学习 · 计算机科学 2025-12-19 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Mohamed Chahine Ghanem

Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing…

定量方法 · 定量生物学 2020-05-21 Xi Yang , Yan Gong , Nida Waheed , Keith March , Jiang Bian , William R. Hogan , Yonghui Wu

Interactive visualization tools are highly desirable to biologist and cancer researchers to explore the complex structures, detect patterns and find out the relationships among bio-molecules responsible for a cancer type. A pathway contains…

定量方法 · 定量生物学 2017-10-23 Vinh Nguyen , Md Yasin Kabir , Tommy Dang

Accurate and early detection of breast cancer is essential for successful treatment. This paper introduces a novel deep-learning approach for improved breast cancer classification in histopathological images, a crucial step in diagnosis.…

图像与视频处理 · 电气工程与系统科学 2024-03-19 Mahdie Ahmadi , Nader Karimi , Shadrokh Samavi

Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a…

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

The integration of multi-omics data has emerged as a promising approach for gaining comprehensive insights into complex diseases such as cancer. This paper proposes a novel approach to identify cancer subtypes through the integration of…

机器学习 · 计算机科学 2023-12-06 Mark Peelen , Leila Bagheriye , Johan Kwisthout

Cancer is known as a disease mainly caused by gene alterations. Discovery of mutated driver pathways or gene sets is becoming an important step to understand molecular mechanisms of carcinogenesis. However, systematically investigating…

基因组学 · 定量生物学 2017-01-02 Junhua Zhang , Shihua Zhang

Identifying altered pathways that are associated with specific cancer types can potentially bring a significant impact on cancer patient treatment. Accurate identification of such key altered pathways information can be used to develop…

机器学习 · 统计学 2017-12-05 Sunho Park , Tae Hyun Hwang

MicroRNAs (miRNAs) are non-coding RNAs with approximately 22 nucleotides (nt) that are derived from precursor molecules. These precursor molecules or pre-miRNAs often fold into stem-loop hairpin structures. However, a large number of…

基因组学 · 定量生物学 2016-10-10 Ling Zhong , Jason T. L. Wang

This research aims to investigate the classification accuracy of various state-of-the-art image classification models across different categories of breast ultrasound images, as defined by the Breast Imaging Reporting and Data System…

图像与视频处理 · 电气工程与系统科学 2023-11-16 Malitha Gunawardhana , Norbert Zolek

Despite recent medical advancements, breast cancer remains one of the most prevalent and deadly diseases among women. Although machine learning-based Computer-Aided Diagnosis (CAD) systems have shown potential to assist radiologists in…

图像与视频处理 · 电气工程与系统科学 2023-08-29 Mohammad Karimzadeh , Aleksandar Vakanski , Min Xian , Boyu Zhang

The work includes a brief overview of the applications of the powerful and easy-to-perform method of Microwave Radiometry (MWR) for the diagnosis of various diseases. The main goal of this paper is to develop a method for diagnosing breast…

医学物理 · 物理学 2024-02-12 Alexander V. Khoperskov , Maxim V. Polyakov

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

图像与视频处理 · 电气工程与系统科学 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Breast density is an important risk factor for breast cancer that also affects the specificity and sensitivity of screening mammography. Current federal legislation mandates reporting of breast density for all women undergoing breast…

Tumor protein P53 is believed to be involved in over half of human cancers cases, the prediction of malignancies plays essential roles not only in advance detection for cancer, but also in discovering effective prevention and treatment of…

计算工程、金融与科学 · 计算机科学 2013-10-09 Ayad Ghany Ismaeel

The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational models in precision cancer diagnostics. This paper introduces Multi-Omics Graph…

Recent advances in biological research have seen the emergence of high-throughput technologies with numerous applications that allow the study of biological mechanisms at an unprecedented depth and scale. A large amount of genomic data is…

机器学习 · 统计学 2020-05-11 Nanwei Wang , Laurent Briollais , Helene Massam

Searching for potential active compounds in large databases is a necessary step to reduce time and costs in modern drug discovery pipelines. Such virtual screening methods seek to provide predictions that allow the search space to be…

生物大分子 · 定量生物学 2023-05-23 Rafael Mena-Yedra , Juana L. Redondo , Horacio Pérez-Sánchez , Pilar M. Ortigosa

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

基因组学 · 定量生物学 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen