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Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…

计算与语言 · 计算机科学 2025-06-16 Jingyu Li , Lingchao Mao , Hairong Wang , Zhendong Wang , Xi Mao , Xuelei Sherry Ni

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Accurate diagnosis of Alzheimer's Disease (AD) entails clinical evaluation of multiple cognition metrics and biomarkers. Metrics such as the Alzheimer's Disease Assessment Scale - Cognitive test (ADAS-cog) comprise multiple subscores that…

机器学习 · 统计学 2017-08-16 Lev E. Givon , Laura J. Mariano , David O'Dowd , John M. Irvine , Abraham R. Schneider

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Alzheimer's Disease (AD) is a prevalent neurodegenerative condition where early detection is vital. Handwriting, often affected early in AD, offers a non-invasive and cost-effective way to capture subtle motor changes. State-of-the-art…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Changqing Gong , Huafeng Qin , Mounîm A. El-Yacoubi

Eye movements are known to reflect cognitive processes in reading, and psychological reading research has shown that eye gaze patterns differ between readers with and without dyslexia. In recent years, researchers have attempted to classify…

计算与语言 · 计算机科学 2022-12-05 Patrick Haller , Andreas Säuberli , Sarah Elisabeth Kiener , Jinger Pan , Ming Yan , Lena Jäger

Robust strategies for Alzheimer's disease (AD) detection are important, given the high prevalence of AD. In this paper, we study the performance and generalizability of three approaches for AD detection from speech on the recent ADReSSo…

计算与语言 · 计算机科学 2022-09-16 Aparna Balagopalan , Jekaterina Novikova

As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…

Ancient Chinese word segmentation (WSG) and part-of-speech tagging (POS) are important to study ancient Chinese, but the amount of ancient Chinese WSG and POS tagging data is still rare. In this paper, we propose a novel augmentation method…

计算与语言 · 计算机科学 2023-03-07 Shuo Feng , Piji Li

This paper presents three hybrid models that directly combine latent Dirichlet allocation and word embedding for distinguishing between speakers with and without Alzheimer's disease from transcripts of picture descriptions. Two of our…

计算与语言 · 计算机科学 2018-08-14 Akshay Budhkar , Frank Rudzicz

Disease modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal observations and provide no uncertainty quantification, rendering them impractical at the critical first…

机器学习 · 计算机科学 2026-04-13 Alireza Moayedikia , Sara Fin , Uffe Kock Wiil

Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…

图像与视频处理 · 电气工程与系统科学 2023-09-12 Huy-Dung Nguyen , Michaël Clément , Vincent Planche , Boris Mansencal , Pierrick Coupé

Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent…

图像与视频处理 · 电气工程与系统科学 2025-02-11 Nasser A Alsadhan

Data sets for identifying Alzheimer's disease (AD) are often relatively sparse, which limits their ability to train generalizable models. Here, we augment such a data set, DementiaBank, with each of two normative data sets, the Wisconsin…

计算与语言 · 计算机科学 2017-12-04 Zeinab Noorian , Chloé Pou-Prom , Frank Rudzicz

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

计算与语言 · 计算机科学 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

Automated speech analysis is a thriving approach to detect early markers of Alzheimer's disease (AD). Yet, recording conditions in most AD datasets are heterogeneous, with patients and controls often evaluated in different acoustic…

The choice of modeling units is crucial for automatic speech recognition (ASR) tasks. In mandarin scenarios, the Chinese characters represent meaning but are not directly related to the pronunciation. Thus only considering the writing of…

计算与语言 · 计算机科学 2022-10-19 Yuting Yang , Binbin Du , Yuke Li

Spoken languages show significant variation across mandarin and accent. Despite the high performance of mandarin automatic speech recognition (ASR), accent ASR is still a challenge task. In this paper, we introduce meta-learning techniques…

声音 · 计算机科学 2023-07-25 Ziwei Zhu , Changhao Shan , Bihong Zhang , Jian Yu

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

计算与语言 · 计算机科学 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni