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Binding affinity prediction of three-dimensional (3D) protein ligand complexes is critical for drug repositioning and virtual drug screening. Existing approaches transform a 3D protein-ligand complex to a two-dimensional (2D) graph, and…

生物大分子 · 定量生物学 2022-10-31 Yiqiang Yi , Xu Wan , Kangfei Zhao , Le Ou-Yang , Peilin Zhao

Gaussian Processes (GPs) are known to provide accurate predictions and uncertainty estimates even with small amounts of labeled data by capturing similarity between data points through their kernel function. However traditional GP kernels…

机器学习 · 计算机科学 2021-11-16 Ankur Mallick , Chaitanya Dwivedi , Bhavya Kailkhura , Gauri Joshi , T. Yong-Jin Han

Gaussian process latent variable models (GPLVMs) are a versatile family of unsupervised learning models commonly used for dimensionality reduction. However, common challenges in modeling data with GPLVMs include inadequate kernel…

机器学习 · 统计学 2024-06-19 Ying Li , Zhidi Lin , Feng Yin , Michael Minyi Zhang

Rolling bearings are subject to various faults due to its long-time operation under harsh environment, which will lead to unexpected breakdown of machinery system and cause severe accidents. Deep learning methods recently have gained…

机器学习 · 计算机科学 2021-09-21 Mingxuan Liang , Kai Zhou

We introduce Similarity Group Proposal Network (SGPN), a simple and intuitive deep learning framework for 3D object instance segmentation on point clouds. SGPN uses a single network to predict point grouping proposals and a corresponding…

计算机视觉与模式识别 · 计算机科学 2019-06-03 Weiyue Wang , Ronald Yu , Qiangui Huang , Ulrich Neumann

The goal of object detection is to determine the class and location of objects in an image. This paper proposes a novel anchor-free, two-stage framework which first extracts a number of object proposals by finding potential corner keypoint…

计算机视觉与模式识别 · 计算机科学 2020-07-29 Kaiwen Duan , Lingxi Xie , Honggang Qi , Song Bai , Qingming Huang , Qi Tian

We introduce G-CNN, an object detection technique based on CNNs which works without proposal algorithms. G-CNN starts with a multi-scale grid of fixed bounding boxes. We train a regressor to move and scale elements of the grid towards…

计算机视觉与模式识别 · 计算机科学 2016-04-27 Mahyar Najibi , Mohammad Rastegari , Larry S. Davis

Current remote sensing image classification problems have to deal with an unprecedented amount of heterogeneous and complex data sources. Upcoming missions will soon provide large data streams that will make land cover/use classification…

机器学习 · 计算机科学 2017-10-04 Pablo Morales-Alvarez , Adrian Perez-Suay , Rafael Molina , Gustau Camps-Valls

Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations. Deep Learning recently has shown promising progress in many…

计算机视觉与模式识别 · 计算机科学 2018-01-08 Mina Rezaei , Haojin Yang , Christoph Meinel

To overcome these obstacles and improve computational accuracy and efficiency, this paper presents the Randomized Radial Basis Function Neural Network (RRNN), an innovative approach explicitly crafted for solving multiscale elliptic…

数值分析 · 数学 2024-07-23 Yuhang Wu , Ziyuan Liu , Wenjun Sun , Xu Qian

Graph Convolutional Networks (GCNs) have received increasing attention in the machine learning community for effectively leveraging both the content features of nodes and the linkage patterns across graphs in various applications. As…

机器学习 · 计算机科学 2021-01-01 Donghan Yu , Ruohong Zhang , Zhengbao Jiang , Yuexin Wu , Yiming Yang

Focal cortical dysplasia (FCD) is a leading cause of drug-resistant focal epilepsy, which can be cured by surgery. These lesions are extremely subtle and often missed even by expert neuroradiologists. "Ground truth" manual lesion masks are…

图像与视频处理 · 电气工程与系统科学 2023-06-06 Hannah Spitzer , Mathilde Ripart , Abdulah Fawaz , Logan Z. J. Williams , MELD project , Emma Robinson , Juan Eugenio Iglesias , Sophie Adler , Konrad Wagstyl

The feed-forward architectures of recently proposed deep super-resolution networks learn representations of low-resolution inputs, and the non-linear mapping from those to high-resolution output. However, this approach does not fully…

计算机视觉与模式识别 · 计算机科学 2018-03-08 Muhammad Haris , Greg Shakhnarovich , Norimichi Ukita

The interdependence between nodes in graphs is key to improve class predictions on nodes and utilized in approaches like Label Propagation (LP) or in Graph Neural Networks (GNN). Nonetheless, uncertainty estimation for non-independent…

Locating 3D objects from a single RGB image via Perspective-n-Point (PnP) is a long-standing problem in computer vision. Driven by end-to-end deep learning, recent studies suggest interpreting PnP as a differentiable layer, allowing for…

计算机视觉与模式识别 · 计算机科学 2023-12-19 Hansheng Chen , Wei Tian , Pichao Wang , Fan Wang , Lu Xiong , Hao Li

Most advances in medical lesion detection network are limited to subtle modification on the conventional detection network designed for natural images. However, there exists a vast domain gap between medical images and natural images where…

计算机视觉与模式识别 · 计算机科学 2020-03-20 Chenhan Jiang , Shaoju Wang , Hang Xu , Xiaodan Liang , Nong Xiao

Reliable classification of benign and malignant lesions in breast ultrasound images can provide an effective and relatively low cost method for early diagnosis of breast cancer. The accuracy of the diagnosis is however highly dependent on…

图像与视频处理 · 电气工程与系统科学 2021-02-24 Elham Yousef Kalaf , Ata Jodeiri , Seyed Kamaledin Setarehdan , Ng Wei Lin , Kartini Binti Rahman , Nur Aishah Taib , Sarinder Kaur Dhillon

We introduce new Gaussian Process (GP) high-order approximations to linear operations that are frequently used in various numerical methods. Our method employs the kernel-based GP regression modeling, a non-parametric Bayesian approach to…

计算物理 · 物理学 2025-06-09 Christopher DeGrendele , Dongwook Lee

Randomized neural networks (RNN) are a variation of neural networks in which the hidden-layer parameters are fixed to randomly assigned values and the output-layer parameters are obtained by solving a linear system by least squares. This…

数值分析 · 数学 2022-06-14 Jingbo Sun , Suchuan Dong , Fei Wang

In this paper we propose novel Deformable Part Networks (DPNs) to learn {\em pose-invariant} representations for 2D object recognition. In contrast to the state-of-the-art pose-aware networks such as CapsNet \cite{sabour2017dynamic} and STN…

机器学习 · 统计学 2018-05-24 Ziming Zhang , Rongmei Lin , Alan Sullivan