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Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

统计力学 · 物理学 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

On the basis of the transport features and experimental phenomena observed in studies of molecular motors, we proposea double-temperature ratchet model of coupled motors to reveal the dynamical mechanism of cooperative transport of motors…

经典物理 · 物理学 2017-02-24 Chen-pu Li , Hong-bin Chen , Zhi-gang Zheng

A ratchet model for coupled Brownian motors, inspired by the motion of individual two-headed molecular motors on cytoskeletal filaments, is proposed. Such motors are modeled as two elastically coupled Brownian particles, each of which moves…

软凝聚态物质 · 物理学 2009-11-07 Debasis Dan , A. M. Jayannavar , Gautam I. Menon

Transport phenomena in spatially periodic systems far from thermal equilibrium are considered. The main emphasize is put on directed transport in so-called Brownian motors (ratchets), i.e. a dissipative dynamics in the presence of thermal…

统计力学 · 物理学 2009-10-31 Peter Reimann

Most computer simulations of molecular dynamics take place under equilibrium conditions--in a closed, isolated system, or perhaps one held at constant temperature or pressure. Sometimes, extra tensions, shears, or temperature gradients are…

统计力学 · 物理学 2022-05-25 Alex Albaugh , Todd R. Gingrich

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

生物物理 · 物理学 2013-07-18 Debashish Chowdhury

We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long-range directional motion of a particle undergoing Brownian random walk in a constant periodic energy potential landscape. The occurrence of…

软凝聚态物质 · 物理学 2009-11-07 Lorenzo Marrucci , Domenico Paparo , Markus Kreuzer

Within the context of the Brownian ratchet model, a molecular rotary system was studied that can perform unidirectional rotations induced by linearly polarized ac fields, and produce positive work under loads. The model is based on the…

统计力学 · 物理学 2017-06-07 Hiroki Tutu , Takehiko Horita , Katsuya Ouchi

The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Brownian motion characterized by coupled diffusion equations. In…

统计力学 · 物理学 2007-05-23 Hong Qian

In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account…

统计力学 · 物理学 2012-11-22 Eva Zimmermann , Udo Seifert

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

统计力学 · 物理学 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

We formulate thermodynamically consistent coarse-graining procedures for molecular systems undergoing thermally and photo-induced transitions: starting from elementary vibronic transitions, we derive effective photo-isomerization reactions…

统计力学 · 物理学 2025-10-08 Francesco Avanzini , Massimiliano Esposito , Emanuele Penocchio

Molecular motors are in charge of almost every process in the life cycle of cells, such as protein synthesis, DNA replication, and cell locomotion, hence being of crucial importance for understanding the cellular dynamics. However, given…

统计力学 · 物理学 2025-09-05 Adrián Nadal-Rosa , Gonzalo Manzano

Simulating electron-nucleus coupled dynamics poses a non-trivial challenge and an important problem in the investigation of ultrafast processes involving coupled electronic and vibrational dynamics. Because irreversibility of the system…

化学物理 · 物理学 2019-04-11 Tatsushi Ikeda , Yoshitaka Tanimura

In recent literature there has been a lot of interest in the phenomena of noise induced transport in the absence of an average bias occurring in spatially periodic systems far from equilibrium. One of the main motivations in this area is to…

生物物理 · 物理学 2007-05-23 Raishma Krishnan , A. M. Jayannavar

We investigated three models of Brownian motors which convert rotational diffusion into directed translational motion by switching on and off a potential. In the first model a spatially asymmetric potential generates directed translational…

统计力学 · 物理学 2009-11-11 Brian Geislinger , Ryoichi Kawai

The pump process of the ratchet model inspired by the $F_o$ rotatory motor of ATP synthase is investigated. In this model there are two kinds of characteristic time. One is dynamical, the relaxation time of the system. Others are chemical,…

生物物理 · 物理学 2007-05-23 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

Thermodynamics of nanoscale devices is an active area of research. Despite their noisy surrounding they often produce mechanical work (e.g. micro-heat engines), display rectified Brownian motion (e.g. molecular motors). This invokes…

统计力学 · 物理学 2018-12-05 Arnab Saha , Rahul Marathe , P. S. Pal , A. M. Jayannavar

We study the flashing ratchet model of a Brownian motor, which consists in cyclical switching between the Fokker-Planck equation with an asymmetric ratchet-like potential and the pure diffusion equation. We show that the motor really…

偏微分方程分析 · 数学 2012-01-13 Dmitry Vorotnikov

We study a Brownian motor, based on cold atoms in optical lattices, where atomic motion can be induced in a controlled manner in an arbitrary direction, by rectification of isotropic random fluctuations. In contrast with ratchet mechanisms,…

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