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We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering:…

应用统计 · 统计学 2010-12-21 Kyung In Kim , Etienne Roquain , Mark Van De Wiel

We study the problem of applying spectral clustering to cluster multi-scale data, which is data whose clusters are of various sizes and densities. Traditional spectral clustering techniques discover clusters by processing a similarity…

机器学习 · 计算机科学 2020-06-09 Xiang Li , Ben Kao , Caihua Shan , Dawei Yin , Martin Ester

Hierarchical clustering is a popular unsupervised data analysis method. For many real-world applications, we would like to exploit prior information about the data that imposes constraints on the clustering hierarchy, and is not captured by…

数据结构与算法 · 计算机科学 2018-07-17 Vaggos Chatziafratis , Rad Niazadeh , Moses Charikar

The variance component tests used in genomewide association studies of thousands of individuals become computationally exhaustive when multiple traits are analysed in the context of omics studies. We introduce two high-throughput algorithms…

计算工程、金融与科学 · 计算机科学 2012-11-13 Diego Fabregat-Traver , Yurii S. Aulchenko , Paolo Bientinesi

Convex clustering is a recent stable alternative to hierarchical clustering. It formulates the recovery of progressively coalescing clusters as a regularized convex problem. While convex clustering was originally designed for handling…

应用统计 · 统计学 2019-12-12 Claire Donnat , Susan Holmes

Background: The nucleus of eukaryotic cells spatially packages chromosomes into a hierarchical and distinct segregation that plays critical roles in maintaining transcription regulation. High-throughput methods of chromosome conformation…

应用统计 · 统计学 2021-04-20 Haipeng Xing , Yingru Wu , Yong Chen , Michael Zhang

Clustering is a fundamental analysis tool aiming at classifying data points into groups based on their similarity or distance. It has found successful applications in all natural and social sciences, including biology, physics, economics,…

信息检索 · 计算机科学 2021-02-24 Wen-Bo Xie , Yan-Li Lee , Cong Wang , Duan-Bing Chen , Tao Zhou

Contrastive deep graph clustering, which aims to divide nodes into disjoint groups via contrastive mechanisms, is a challenging research spot. Among the recent works, hard sample mining-based algorithms have achieved great attention for…

机器学习 · 计算机科学 2023-01-31 Yue Liu , Xihong Yang , Sihang Zhou , Xinwang Liu , Zhen Wang , Ke Liang , Wenxuan Tu , Liang Li , Jingcan Duan , Cancan Chen

We propose a nearest neighbor based clustering algorithm that results in a naturally defined hierarchy of clusters. In contrast to the agglomerative and divisive hierarchical clustering algorithms, our approach is not dependent on the…

数据结构与算法 · 计算机科学 2022-03-16 Kaan Gokcesu , Hakan Gokcesu

Recent works on Hierarchical Clustering (HC), a well-studied problem in exploratory data analysis, have focused on optimizing various objective functions for this problem under arbitrary similarity measures. In this paper we take the first…

数据结构与算法 · 计算机科学 2018-12-31 Moses Charikar , Vaggos Chatziafratis , Rad Niazadeh , Grigory Yaroslavtsev

This paper presents a hierarchical low-rank decomposition algorithm assuming any matrix element can be computed in $O(1)$ time. The proposed algorithm computes rank-revealing decompositions of sub-matrices with a blocked adaptive cross…

$\textbf{Graph Coarsening (GC)}$ is a prominent graph reduction technique that compresses large graphs to enable efficient learning and inference. However, existing GC methods generate only one coarsened graph per run and must recompute…

社会与信息网络 · 计算机科学 2025-05-23 Mohit Kataria , Shreyash Bhilwade , Sandeep Kumar , Jayadeva

Chromosome conformation capture experiments such as Hi-C are used to map the three-dimensional spatial organization of genomes. One specific feature of the 3D organization is known as topologically associating domains (TADs), which are…

应用统计 · 统计学 2019-10-18 Y. X. Rachel Wang , Purnamrita Sarkar , Oana Ursu , Anshul Kundaje , Peter J. Bickel

Attributed networks containing entity-specific information in node attributes are ubiquitous in modeling social networks, e-commerce, bioinformatics, etc. Their inherent network topology ranges from simple graphs to hypergraphs with…

社会与信息网络 · 计算机科学 2024-10-08 Yiran Li , Gongyao Guo , Jieming Shi , Renchi Yang , Shiqi Shen , Qing Li , Jun Luo

In this paper, we propose an unsupervised face clustering algorithm called "Proximity-Aware Hierarchical Clustering" (PAHC) that exploits the local structure of deep representations. In the proposed method, a similarity measure between deep…

计算机视觉与模式识别 · 计算机科学 2017-03-16 Wei-An Lin , Jun-Cheng Chen , Rama Chellappa

This paper studies the problem of graph-level clustering, which is a novel yet challenging task. This problem is critical in a variety of real-world applications such as protein clustering and genome analysis in bioinformatics. Recent years…

机器学习 · 计算机科学 2023-03-09 Wei Ju , Yiyang Gu , Binqi Chen , Gongbo Sun , Yifang Qin , Xingyuming Liu , Xiao Luo , Ming Zhang

We propose a decentralized caching policy for wireless heterogeneous networks that makes content placement decisions based on pairwise interactions between cache nodes. We call our proposed scheme {\gamma}-exclusion cache placement (GEC),…

信息论 · 计算机科学 2021-01-08 Derya Malak , Muriel Médard , Jeffrey G. Andrews

We propose a clustering-based generalized low rank approximation method, which takes advantage of appealing features from both the generalized low rank approximation of matrices (GLRAM) and cluster analysis. It exploits a more general form…

最优化与控制 · 数学 2025-02-21 Yujun Zhu , Jie Zhu , Hizba Arshad , Zhongming Wang , Ju Ming

Clustering analysis is of substantial significance for data mining. The properties of big data raise higher demand for more efficient and economical distributed clustering methods. However, existing distributed clustering methods mainly…

分布式、并行与集群计算 · 计算机科学 2023-07-03 Yifeng Xiao , Jiang Xue , Deyu Meng

Motivation: Hi-C matrices are cornerstones for qualitative and quantitative studies of genome folding, from its territorial organization to compartments and topological domains. The high dynamic range of genomic distances probed in Hi-C…

基因组学 · 定量生物学 2021-01-27 Stefano Franzini , Marco Di Stefano , Cristian Micheletti