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Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

光学 · 物理学 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

In this thesis we discuss architectural designs and training methods for a neural network to have the ability of dissecting an image into objects of interest without supervision. The main challenge in 2D unsupervised object segmentation is…

计算机视觉与模式识别 · 计算机科学 2025-04-28 Sara Sabour

Single-pixel imaging has emerged as a key technique in fluorescence microscopy, where fast acquisition and reconstruction are crucial. In this context, images are reconstructed from linearly compressed measurements. In practice, total…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Serban C. Tudosie , Valerio Gandolfi , Shivaprasad Varakkoth , Andrea Farina , Cosimo D'Andrea , Simon Arridge

Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

图像与视频处理 · 电气工程与系统科学 2023-08-07 Fang-Cheng Yeh

Blind image deblurring is an important yet very challenging problem in low-level vision. Traditional optimization based methods generally formulate this task as a maximum-a-posteriori estimation or variational inference problem, whose…

图像与视频处理 · 电气工程与系统科学 2021-06-08 Hui Wang , Zongsheng Yue , Qian Zhao , Deyu Meng

Colloidoscope is a deep learning pipeline employing a 3D residual Unet architecture, designed to enhance the tracking of dense colloidal suspensions through confocal microscopy. This methodology uses a simulated training dataset that…

Undersampling the k-space data is widely adopted for acceleration of Magnetic Resonance Imaging (MRI). Current deep learning based approaches for supervised learning of MRI image reconstruction employ real-valued operations and…

计算机视觉与模式识别 · 计算机科学 2018-07-11 Muneer Ahmad Dedmari , Sailesh Conjeti , Santiago Estrada , Phillip Ehses , Tony Stöcker , Martin Reuter

Recently, deep learning approaches have become the main research frontier for biological image reconstruction and enhancement problems thanks to their high performance, along with their ultra-fast inference times. However, due to the…

图像与视频处理 · 电气工程与系统科学 2022-03-18 Mehmet Akçakaya , Burhaneddin Yaman , Hyungjin Chung , Jong Chul Ye

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

光学 · 物理学 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

Phase retrieval, the problem of recovering lost phase information from measured intensity alone, is an inverse problem that is widely faced in various imaging modalities ranging from astronomy to nanoscale imaging. The current process of…

图像与视频处理 · 电气工程与系统科学 2024-06-12 Henry Chan , Youssef S. G. Nashed , Saugat Kandel , Stephan Hruszkewycz , Subramanian Sankaranarayanan , Ross J. Harder , Mathew J. Cherukara

Due to the current lack of large-scale datasets at the million-scale level, tasks involving panoramic images predominantly rely on existing two-dimensional pre-trained image benchmark models as backbone networks. However, these networks are…

计算机视觉与模式识别 · 计算机科学 2025-07-15 Jingguo Liu , Han Yu , Shigang Li , Jianfeng Li

To generalize to novel visual scenes with new viewpoints and new object poses, a visual system needs representations of the shapes of the parts of an object that are invariant to changes in viewpoint or pose. 3D graphics representations…

计算机视觉与模式识别 · 计算机科学 2019-05-29 Boyang Deng , Simon Kornblith , Geoffrey Hinton

Consistent in-focus input imagery is an essential precondition for machine vision systems to perceive the dynamic environment. A defocus blur severely degrades the performance of vision systems. To tackle this problem, we propose a…

图像与视频处理 · 电气工程与系统科学 2021-03-11 Jisheng Li , Qi Dai , Jiangtao Wen

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

图像与视频处理 · 电气工程与系统科学 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang

Since it is usually difficult to capture an all-in-focus image of a 3D scene directly, various multi-focus image fusion methods are employed to generate it from several images focusing at different depths. However, the performance of…

计算机视觉与模式识别 · 计算机科学 2019-11-05 Haoyu Ma , Juncheng Zhang , Shaojun Liu , Qingmin Liao

The trade-off between throughput and image quality is an inherent challenge in microscopy. To improve throughput, compressive imaging under-samples image signals; the images are then computationally reconstructed by solving a regularized…

图像与视频处理 · 电气工程与系统科学 2023-03-07 Udith Haputhanthri , Andrew Seeber , Dushan Wadduwage

Due to the computational complexity of 3D medical image segmentation, training with downsampled images is a common remedy for out-of-memory errors in deep learning. Nevertheless, as standard spatial convolution is sensitive to variations in…

图像与视频处理 · 电气工程与系统科学 2023-10-09 Ken C. L. Wong , Hongzhi Wang , Tanveer Syeda-Mahmood

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

图像与视频处理 · 电气工程与系统科学 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

Multi-contrast MRI images provide complementary contrast information about the characteristics of anatomical structures and are commonly used in clinical practice. Recently, a multi-flip-angle (FA) and multi-echo GRE method (MULTIPLEX MRI)…

图像与视频处理 · 电气工程与系统科学 2021-05-19 Eric Z. Chen , Yongquan Ye , Xiao Chen , Jingyuan Lyu , Zhongqi Zhang , Yichen Hu , Terrence Chen , Jian Xu , Shanhui Sun

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

光学 · 物理学 2022-01-26 Yi Xue , David Ren , Laura Waller