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Despite their significant advantages over competing technologies, nanopore sequencers are plagued by high error rates, due to physical characteristics of the nanopore and inherent noise in the biological processes. It is thus paramount not…

信息论 · 计算机科学 2025-10-27 Anisha Banerjee , Yonatan Yehezkeally , Antonia Wachter-Zeh , Eitan Yaakobi

DNA strands serve as a storage medium for $4$-ary data over the alphabet $\{A,T,G,C\}$. DNA data storage promises formidable information density, long-term durability, and ease of replicability. However, information in this intriguing…

信息论 · 计算机科学 2024-08-06 Canberk İrimağzı , Yusuf Uslan , Ahmed Hareedy

Data storage in DNA is developing as a possible solution for archival digital data. Recently, to further increase the potential capacity of DNA-based data storage systems, the combinatorial composite DNA synthesis method was suggested. This…

信息论 · 计算机科学 2024-05-28 Omer Sabary , Inbal Preuss , Ryan Gabrys , Zohar Yakhini , Leon Anavy , Eitan Yaakobi

Synthetic DNA can in principle be used for the archival storage of arbitrary data. Because errors are introduced during DNA synthesis, storage, and sequencing, an error-correcting code (ECC) is necessary for error-free recovery of the data.…

定量方法 · 定量生物学 2018-12-05 William H. Press , John A. Hawkins

We describe a strategy for constructing codes for DNA-based information storage by serial composition of weighted finite-state transducers. The resulting state machines can integrate correction of substitution errors; synchronization by…

信息论 · 计算机科学 2016-11-18 Ian Holmes

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

新兴技术 · 计算机科学 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

As the global need for large-scale data storage is rising exponentially, existing storage technologies are approaching their theoretical and functional limits in terms of density and energy consumption, making DNA based storage a potential…

新兴技术 · 计算机科学 2021-10-12 Yotam Nahum , Eyar Ben-Tolila , Leon Anavy

Erasure coding techniques are getting integrated in networked distributed storage systems as a way to provide fault-tolerance at the cost of less storage overhead than traditional replication. Redundancy is maintained over time through…

分布式、并行与集群计算 · 计算机科学 2012-06-12 Lluis Pamies-Juarez , Frédérique Oggier , Anwitaman Datta

We consider the problem of designing low-redundancy codes in settings where one must correct deletions in conjunction with substitutions or adjacent transpositions; a combination of errors that is usually observed in DNA-based data storage.…

信息论 · 计算机科学 2021-12-21 Ryan Gabrys , Venkatesan Guruswami , João Ribeiro , Ke Wu

Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging…

信息论 · 计算机科学 2020-11-12 Yuanyuan Tang , Farzad Farnoud

An indel refers to a single insertion or deletion, while an edit refers to a single insertion, deletion or substitution. In this paper, we investigate codes that combat either a single indel or a single edit and provide linear-time…

信息论 · 计算机科学 2019-10-16 Kui Cai , Yeow Meng Chee , Ryan Gabrys , Han Mao Kiah , Tuan Thanh Nguyen

Regenerating codes are a class of codes proposed for providing reliability of data and efficient repair of failed nodes in distributed storage systems. In this paper, we address the fundamental problem of handling errors and erasures during…

信息论 · 计算机科学 2015-03-20 K. V. Rashmi , Nihar B. Shah , Kannan Ramchandran , P. Vijay Kumar

Distributed storage systems often introduce redundancy to increase reliability. When coding is used, the repair problem arises: if a node storing encoded information fails, in order to maintain the same level of reliability we need to…

信息论 · 计算机科学 2010-04-27 Alexandros G. Dimakis , Kannan Ramchandran , Yunnan Wu , Changho Suh

In order to achieve fault tolerance, highly reliable system often require the ability to detect errors as soon as they occur and prevent the speared of erroneous information throughout the system. Thus, the need for codes capable of…

信息论 · 计算机科学 2010-02-08 Muzhir Al-Ani , Qeethara Al-Shayea

The increasing demand for data storage has prompted the exploration of new techniques, with molecular data storage being a promising alternative. In this work, we develop coding schemes for a new storage paradigm that can be represented as…

信息论 · 计算机科学 2025-10-30 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

Distributed storage systems provide reliable access to data through redundancy spread over individually unreliable nodes. Application scenarios include data centers, peer-to-peer storage systems, and storage in wireless networks. Storing…

网络与互联网体系结构 · 计算机科学 2008-03-06 Alexandros G. Dimakis , P. Brighten Godfrey , Yunnan Wu , Martin J. Wainwright , Kannan Ramchandran

Noisy shuffling channels capture the main characteristics of DNA storage systems where distinct segments of data are received out of order, after being corrupted by substitution errors. For realistic schemes with short-length segments,…

信息论 · 计算机科学 2024-10-07 Javad Haghighat , Tolga M. Duman

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire…

信息论 · 计算机科学 2025-10-29 Frederik Walter , Omer Sabary , Antonia Wachter-Zeh , Eitan Yaakobi

Recently, DNA storage has surfaced as a promising alternative for data storage, presenting notable benefits in terms of storage capacity, cost-effectiveness in maintenance, and the capability for parallel replication. Mathematically, the…

信息论 · 计算机科学 2024-01-31 Yi Lu , Yun Ma , Chenghao Li , Xin Zhang , Guangxiang Si

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

信息论 · 计算机科学 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh