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Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, with lung metastases being the most common site of distant spread and significantly worsening prognosis. Despite the growing availability of clinical and…

组织与器官 · 定量生物学 2025-01-22 Jeff J. H. Kim , George R. Nahass , Yang Dai , Theja Tulabandhula

Precision medicine promises to transform health care by offering individualised treatments that dramatically improve clinical outcomes. A necessary prerequisite is to identify subgroups of patients who respond differently to different…

机器学习 · 计算机科学 2026-03-03 Adam Marcus , Paul Agapow

Ethnicity is a key demographic attribute of human beings and it plays a vital role in automatic facial recognition and have extensive real world applications such as Human Computer Interaction (HCI); demographic based classification;…

计算机视觉与模式识别 · 计算机科学 2017-11-01 Inzamam Anwar , Naeem Ul Islam

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

Biomarkers which predict patient's survival can play an important role in medical diagnosis and treatment. How to select the significant biomarkers from hundreds of protein markers is a key step in survival analysis. In this paper a novel…

神经与进化计算 · 计算机科学 2013-06-03 Yihui Liu , Uwe Aickelin , Jan Feyereisl , Lindy G. Durrant

Cancer is a complex disease with significant social and economic impact. Advancements in high-throughput molecular assays and the reduced cost for performing high-quality multi-omics measurements have fuelled insights through machine…

机器学习 · 计算机科学 2022-06-28 Pedro Henrique da Costa Avelar , Roman Laddach , Sophia Karagiannis , Min Wu , Sophia Tsoka

With a high rate of morbidity and mortality, colorectal cancer (CRC) ranks third in mortality among cancers. By analyzing the texture properties of images and quantifying the heterogeneity of tumors, radiomics and radiogenomics are…

医学物理 · 物理学 2024-06-25 Parsa Karami , Reza Elahi

The genomic evolution inherent to cancer relates directly to a renewed focus on the voluminous next generation sequencing (NGS) data, and machine learning for the inference of explanatory models of how the (epi)genomic events are…

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

图像与视频处理 · 电气工程与系统科学 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Pancreatic cancers have one of the worst prognoses compared to other cancers, as they are diagnosed when cancer has progressed towards its latter stages. The current manual histological grading for diagnosing pancreatic adenocarcinomas is…

图像与视频处理 · 电气工程与系统科学 2022-06-20 Biraja Ghoshal , Bhargab Ghoshal , Allan Tucker

Background: Stratifying cancer patients according to risk of relapse can personalize their care. In this work, we provide an answer to the following research question: How to utilize machine learning to estimate probability of relapse in…

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

机器学习 · 计算机科学 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an…

分子网络 · 定量生物学 2014-08-12 Edwin Wang , Naif Zaman , Shauna Mcgee , Jean-Sébastien Milanese , Ali Masoudi-Nejad , Maureen O'Connor

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

机器学习 · 统计学 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

Objectives: Lung cancer poses a significant global health challenge, necessitating improved prognostic methods for personalized treatment. This study introduces a censor-aware semi-supervised learning (SSL) framework that integrates…

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

统计方法学 · 统计学 2026-01-12 Saku Suorsa , Aki Vehtari

We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (3 months) of the patients by analyzing free-text clinical notes in the…

Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often…

机器学习 · 计算机科学 2024-08-29 Alek Fröhlich , Thiago Ramos , Gustavo Cabello , Isabela Buzatto , Rafael Izbicki , Daniel Tiezzi

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

机器学习 · 计算机科学 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

机器学习 · 计算机科学 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré