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Skin cancer is the most common human malignancy(American Cancer Society) which is primarily diagnosed visually, starting with an initial clinical screening and followed potentially by dermoscopic(related to skin) analysis, a biopsy and…

图像与视频处理 · 电气工程与系统科学 2022-02-03 Kartikeya Agarwal , Tismeet Singh

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

计算机视觉与模式识别 · 计算机科学 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose a fully automated pipeline for oral cancer detection on…

图像与视频处理 · 电气工程与系统科学 2020-09-14 Jiahao Lu , Nataša Sladoje , Christina Runow Stark , Eva Darai Ramqvist , Jan-Michaél Hirsch , Joakim Lindblad

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Vision Transformers (ViTs) have ushered in a new era in computer vision, showcasing unparalleled performance in many challenging tasks. However, their practical deployment in computational pathology has largely been constrained by the sheer…

计算机视觉与模式识别 · 计算机科学 2023-12-21 Clément Grisi , Geert Litjens , Jeroen van der Laak

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Automated grading of prostate cancer histopathology images is a challenging task, with one key challenge being the scarcity of annotations down to the level of regions of interest (strong labels), as typically the prostate cancer Gleason…

计算机视觉与模式识别 · 计算机科学 2018-11-20 Eirini Arvaniti , Manfred Claassen

Women infected by the Human papilloma virus are at an increased risk to develop cervical intraepithalial neoplasia lesions (CIN). CIN are classified into three grades of increasing severity (CIN-1, CIN-2, and CIN-3) and can eventually…

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

计算机视觉与模式识别 · 计算机科学 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Computer vision models are increasingly capable of classifying ovarian epithelial cancer subtypes, but they differ from pathologists by processing small tissue patches at a single resolution. Multi-resolution graph models leverage the…

图像与视频处理 · 电气工程与系统科学 2024-07-26 Jack Breen , Katie Allen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

The evaluation of the Human Epidermal growth factor Receptor-2 (HER2) expression is an important prognostic biomarker for breast cancer treatment selection. However, HER2 scoring has notoriously high interobserver variability due to stain…

图像与视频处理 · 电气工程与系统科学 2022-11-18 Manh Dan Pham , Cyprien Tilmant , Stéphanie Petit , Isabelle Salmon , Saima Ben Hadj , Rutger H. J. Fick

Hepatocellular Carcinoma diagnosis relies heavily on the interpretation of gigapixel Whole Slide Images. However, current computational approaches are constrained by fixed-resolution processing mechanisms and inefficient feature…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Yuxuan Yang , Zhonghao Yan , Yi Zhang , Bo Yun , Muxi Diao , Guowei Zhao , Kongming Liang , Wenbin Li , Zhanyu Ma

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

图像与视频处理 · 电气工程与系统科学 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

The boundary of tumors (hepatocellular carcinoma, or HCC) contains rich semantics: capsular invasion, visibility, smoothness, folding and protuberance, etc. Capsular invasion on tumor boundary has proven to be clinically correlated with the…

计算机视觉与模式识别 · 计算机科学 2021-03-10 Jieneng Chen , Ke Yan , Yu-Dong Zhang , Youbao Tang , Xun Xu , Shuwen Sun , Qiuping Liu , Lingyun Huang , Jing Xiao , Alan L. Yuille , Ya Zhang , Le Lu

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Breast cancer is the most prevalent cancer in women worldwide. Histopathology image analysis serves as the gold standard for cancer diagnosis. In this regard, whole-slide imaging (WSI), a revolutionary technology in digital pathology,…

统计方法学 · 统计学 2026-04-21 Baichen Yu , Xuetong Li , Jing Zhou , Hansheng Wang

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

图像与视频处理 · 电气工程与系统科学 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang