相关论文: Primary and secondary components of nerve signals
The distinctive features of passing the two-component extremely short pulses through the nonlinear media are discussed. The equations considered describe the propagation in the two-level anisotropic medium of the electromagnetic pulses…
Biochemical signalling cascades transduce extracellular stimuli into cellular responses through sequences of discrete, node-to-node activations. While signal fidelity depends critically on local interaction kinetics, the mechanisms…
Autonomous oscillations in biological systems may have a biochemical origin or result from an interplay between force-generating and visco-elastic elements. In molecular motor assemblies the force-generating elements are molecular engines…
A study is made of how active membrane proteins can modify the long wavelength mechanics of fluid membranes. The activity of the proteins is modelled as disturbing the protein surroundings through non-local force distributions of which a…
Neuromorphic engineering is a rapidly developing field that aims to take inspiration from the biological organization of neural systems to develop novel technology for computing, sensing, and actuating. The unique properties of such systems…
Both action potentials and mechanosensitive signalling are an important communication mechanisms in plants. Considering an information theoretic framework, this paper explores the effective range of multiple action potentials for a long…
Starting from the wave equation for a medium with material properties that vary periodically, we study a system of recurrence relations that describe propagation of wave packets that oscillate on the microscale (i.e. on lengths of the order…
We look at the problem of signal transduction by extracellular agonist binding to a receptor protein at the membrane (sensor) via binding of G-proteins (effectors) to a highly integrative target molecule, such as the second messenger cAMP…
In the average profiles of several radio pulsars, the main pulse is accompanied by the preceding component. This so called precursor is known for its distinctive polarization, spectral, and fluctuation properties. Recent single-pulse…
A common feature of biological networks is the geometric property of self-similarity. Molecular regulatory networks through to circulatory systems, nervous systems, social systems and ecological trophic networks, show self-similar…
The human brain is one of the most complex and intriguing scientific topics. The most established theory on neuronal communication is a pure electrical model based on the propagation of intracell cationic charges along the neurons. Here we…
Metamaterials are artificial composite structures designed for controlling waves or fields, and exhibit interaction phenomena that are unexpected on the basis of their chemical constituents. These phenomena are encoded in effective material…
One form of big data are signals - time series of consecutive values. In physical experiments, billions of values can now be measured within a second. Signals of heart and brain in intensive care, as well as seismic waves, are measured with…
In our previous work, we proposed a novel neuron model based on symmetric differential equations and demonstrated its potential as an efficient signal propagator. Building upon that foundation, the present study delves deeper into the…
This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…
Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…
A particle switching between two sides of a symmetric system in interaction with a continuum exhibits a telegraph-like time development without the need of the Born-Bohr principle of reduction on eigenstates of the measuring equipment. The…
We demonstrate experimentally the possibility of revealing fluctuations in the eigenfrequency of a resonator when the frequency noise is of the telegraph type. Using a resonantly driven micromechanical resonator, we show that the…
Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…
Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the…