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The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

机器学习 · 计算机科学 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

As in many fields of medical research, survival analysis has witnessed a growing interest in the application of deep learning techniques to model complex, high-dimensional, heterogeneous, incomplete, and censored medical data. Current…

机器学习 · 计算机科学 2023-12-25 Patricia A. Apellániz , Juan Parras , Santiago Zazo

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

The application of deep learning in survival analysis (SA) allows utilizing unstructured and high-dimensional data types uncommon in traditional survival methods. This allows to advance methods in fields such as digital health, predictive…

机器学习 · 计算机科学 2021-11-18 Tobias Weber , Michael Ingrisch , Bernd Bischl , David Rügamer

Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

机器学习 · 计算机科学 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

Variational autoencoders (VAEs) are a popular generative model used to approximate distributions. The encoder part of the VAE is used in amortized learning of latent variables, producing a latent representation for data samples. Recently,…

机器学习 · 统计学 2023-05-12 Daniel G. Edelberg , Roy R. Lederman

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

机器学习 · 统计学 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

Artificial Intelligence in healthcare is a new and exciting frontier and the possibilities are endless. With deep learning approaches beating human performances in many areas, the logical next step is to attempt their application in the…

机器学习 · 计算机科学 2018-08-21 Ally Salim

This paper provides a comprehensive analysis of variational inference in latent variable models for survival analysis, emphasizing the distinctive challenges associated with applying variational methods to survival data. We identify a…

机器学习 · 计算机科学 2025-06-05 Chuanhui Liu , Xiao Wang

Variational Autoencoders (VAEs) are well-established as a principled approach to probabilistic unsupervised learning with neural networks. Typically, an encoder network defines the parameters of a Gaussian distributed latent space from…

机器学习 · 计算机科学 2025-05-16 Alan Jeffares , Liyuan Liu

Variational autoencoders (VAEs) have been used extensively to discover low-dimensional latent factors governing neural activity and animal behavior. However, without careful model selection, the uncovered latent factors may reflect noise in…

机器学习 · 计算机科学 2023-12-13 Julia Huiming Wang , Dexter Tsin , Tatiana Engel

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

基因组学 · 定量生物学 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

In healthcare, risk assessment of patient outcomes has been based on survival analysis for a long time, i.e. modeling time-to-event associations. However, conventional approaches rely on data from a single time-point, making them suboptimal…

机器学习 · 计算机科学 2026-02-20 Mine Öğretir , Miika Koskinen , Juha Sinisalo , Risto Renkonen , Harri Lähdesmäki

Learning interpretable and disentangled representations of data is a key topic in machine learning research. Variational Autoencoder (VAE) is a scalable method for learning directed latent variable models of complex data. It employs a clear…

机器学习 · 计算机科学 2020-06-04 Andriy Serdega , Dae-Shik Kim

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Classical methods for model order selection often fail in scenarios with low SNR or few snapshots. Deep learning-based methods are promising alternatives for such challenging situations as they compensate lack of information in the…

信号处理 · 电气工程与系统科学 2023-12-07 Michael Baur , Franz Weißer , Benedikt Böck , Wolfgang Utschick

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

Variational autoencoders (VAE) represent a popular, flexible form of deep generative model that can be stochastically fit to samples from a given random process using an information-theoretic variational bound on the true underlying…

机器学习 · 计算机科学 2019-10-08 Bin Dai , Yu Wang , John Aston , Gang Hua , David Wipf
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