相关论文: An interpretable multiple kernel learning approach…

Extracting an understanding of the underlying system from high dimensional data is a growing problem in science. Discovering informative and meaningful features is crucial for clustering, classification, and low dimensional data embedding.…

The progression of chronic diseases often follows highly variable trajectories, and the underlying factors remain poorly understood. Standard mixed-effects models typically represent inter-patient differences as random deviations around a…

Federated learning and its application to medical image segmentation have recently become a popular research topic. This training paradigm suffers from statistical heterogeneity between participating institutions' local datasets, incurring…

Essential protein plays a crucial role in the process of cell life. The identification of essential proteins can not only promote the development of drug target technology, but also contribute to the mechanism of biological evolution. There…

Subspace clustering is to find underlying low-dimensional subspaces and cluster the data points correctly. In this paper, we propose a novel multi-view subspace clustering method. Most existing methods suffer from two critical issues.…

The linking genotype to phenotype is the fundamental aim of modern genetics. We focus on study of links between gene expression data and phenotype data through integrative analysis. We propose three approaches. 1) The inherent complexity of…

Purpose: The primary goal of this study is to explore the application of evaluation metrics to different clustering algorithms using the data provided from the Canadian Longitudinal Study (CLSA), focusing on cognitive features. The…

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Cancer is a fatal disease caused by a combination of genetic diseases and a variety of biochemical abnormalities. Lung and colon cancer have emerged as two of the leading causes of death and disability in humans. The histopathological…

A novel nonparametric clustering algorithm is proposed using the interpoint distances between the members of the data to reveal the inherent clustering structure existing in the given set of data, where we apply the classical nonparametric…

Data clustering has been widely used in data analysis and classification. In the present work, a method based on dynamic quantum clustering is proposed for the segmentation and analysis of brain tumor MRI. The results open the possibility…

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Significant advances in biotechnology have allowed for simultaneous measurement of molecular data points across multiple genomic and transcriptomic levels from a single tumor/cancer sample. This has motivated systematic approaches to…

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

For multi-modal magnetic resonance (MR) brain tumor image segmentation, current methods usually directly extract the discriminative features from input images for tumor sub-region category determination and localization. However, the impact…

Brain tumor is a common and fatal form of cancer which affects both adults and children. The classification of brain tumors into different types is hence a crucial task, as it greatly influences the treatment that physicians will prescribe.…

Combining information from different sources is a common way to improve classification accuracy in Brain-Computer Interfacing (BCI). For instance, in small sample settings it is useful to integrate data from other subjects or sessions in…

Advances in data collection in radiation therapy have led to an abundance of opportunities for applying data mining and machine learning techniques to promote new data-driven insights. In light of these advances, supporting collaboration…

Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…

High-resolution mapping of cells and tissue structures provides a foundation for developing interpretable machine-learning models for computational pathology. Deep learning algorithms can provide accurate mappings given large numbers of…