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Although rare diseases are characterized by low prevalence, approximately 300 million people are affected by a rare disease. The early and accurate diagnosis of these conditions is a major challenge for general practitioners, who do not…

计算与语言 · 计算机科学 2021-11-12 Isabel Segura-Bedmar , David Camino-Perdonas , Sara Guerrero-Aspizua

Physics-informed machine learning (PIML) is emerging as a potentially transformative paradigm for modeling complex biomedical systems by integrating parameterized physical laws with data-driven methods. Here, we review three main classes of…

机器学习 · 计算机科学 2025-10-08 Nazanin Ahmadi , Qianying Cao , Jay D. Humphrey , George Em Karniadakis

Objective:Develop and validate an algorithm for analyzing the layout of PDF clinical documents to improve the performance of downstream natural language processing tasks. Materials and Methods: We designed an algorithm to process clinical…

Automatic extraction of clinical concepts is an essential step for turning the unstructured data within a clinical note into structured and actionable information. In this work, we propose a clinical concept extraction model for automatic…

计算与语言 · 计算机科学 2018-11-28 Henghui Zhu , Ioannis Ch. Paschalidis , Amir Tahmasebi

Individual's general well-being is greatly impacted by mental health conditions including depression and Post-Traumatic Stress Disorder (PTSD), underscoring the importance of early detection and precise diagnosis in order to facilitate…

In this work, we present a weakly supervised sentence extraction technique for identifying important sentences in scientific papers that are worthy of inclusion in the abstract. We propose a new attention based deep learning architecture…

信息检索 · 计算机科学 2018-02-14 Parth Mehta , Gaurav Arora , Prasenjit Majumder

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…

The clinical named entity recognition (CNER) task seeks to locate and classify clinical terminologies into predefined categories, such as diagnostic procedure, disease disorder, severity, medication, medication dosage, and sign symptom.…

计算与语言 · 计算机科学 2021-06-25 Yichao Zhou , Chelsea Ju , J. Harry Caufield , Kevin Shih , Calvin Chen , Yizhou Sun , Kai-Wei Chang , Peipei Ping , Wei Wang

The field of clinical natural language processing has been advanced significantly since the introduction of deep learning models. The self-supervised representation learning and the transfer learning paradigm became the methods of choice in…

计算与语言 · 计算机科学 2020-04-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Alejo Nevado-Holgado

The human brain represents an object by small elements and distinguishes two objects based on the difference in elements. Discovering the distinctive elements of high-dimensional datasets is therefore critical in numerous perception-driven…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Md Tauhidul Islam , Lei Xing

Interventional cancer clinical trials are generally too restrictive, and some patients are often excluded on the basis of comorbidity, past or concomitant treatments, or the fact that they are over a certain age. The efficacy and safety of…

计算与语言 · 计算机科学 2018-07-26 Aurelia Bustos , Antonio Pertusa

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

计算机视觉与模式识别 · 计算机科学 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

This study is dedicated to exploring the application of prompt learning methods to advance Named Entity Recognition (NER) within the medical domain. In recent years, the emergence of large-scale models has driven significant progress in NER…

计算与语言 · 计算机科学 2025-06-04 Jinzhu Yang

A systematic review identifies and collates various clinical studies and compares data elements and results in order to provide an evidence based answer for a particular clinical question. The process is manual and involves lot of time. A…

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

计算工程、金融与科学 · 计算机科学 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li

Advanced diffusion models have made notable progress in text-to-image compositional generation. However, it is still a challenge for existing models to achieve text-image alignment when confronted with complex text prompts. In this work, we…

计算机视觉与模式识别 · 计算机科学 2025-05-07 Chang Xie , Chenyi Zhuang , Pan Gao

Objective: We investigate whether deep learning techniques for natural language processing (NLP) can be used efficiently for patient phenotyping. Patient phenotyping is a classification task for determining whether a patient has a medical…

Neural network-based representations ("embeddings") have dramatically advanced natural language processing (NLP) tasks, including clinical NLP tasks such as concept extraction. Recently, however, more advanced embedding methods and…

计算与语言 · 计算机科学 2019-08-15 Yuqi Si , Jingqi Wang , Hua Xu , Kirk Roberts

De-identification is the task of identifying protected health information (PHI) in the clinical text. Existing neural de-identification models often fail to generalize to a new dataset. We propose a simple yet effective data augmentation…

计算与语言 · 计算机科学 2020-10-13 Xiang Yue , Shuang Zhou

We propose a method for learning disentangled representations of texts that code for distinct and complementary aspects, with the aim of affording efficient model transfer and interpretability. To induce disentangled embeddings, we propose…

计算与语言 · 计算机科学 2018-09-05 Sarthak Jain , Edward Banner , Jan-Willem van de Meent , Iain J. Marshall , Byron C. Wallace