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Experimental design is crucial for inference where limitations in the data collection procedure are present due to cost or other restrictions. Optimal experimental designs determine parameters that in some appropriate sense make the data…

机器学习 · 统计学 2016-03-11 Panagiotis Tsilifis , Roger G. Ghanem , Paris Hajali

Risk prediction models are often advertised as deterministic functions that map covariates to predicted risks. However, they are typically trained using finite samples, and as such, their predictions are inherently uncertain. This…

统计方法学 · 统计学 2025-06-03 Abdollah Safari , Paul Gustafson , Mohsen Sadatsafavi

We introduce a method combining variational autoencoders (VAEs) and deep metric learning to perform Bayesian optimisation (BO) over high-dimensional and structured input spaces. By adapting ideas from deep metric learning, we use label…

We present a new method for improving the performances of variational autoencoder (VAE). In addition to enforcing the deep feature consistent principle thus ensuring the VAE output and its corresponding input images to have similar deep…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Xianxu Hou , Ke Sun , Linlin Shen , Guoping Qiu

Bayesian experimental design (BED) provides a principled framework for optimizing data collection by choosing experiments that are maximally informative about unknown parameters. However, existing methods cannot deal with the joint…

机器学习 · 统计学 2026-01-30 Sara Pérez-Vieites , Sahel Iqbal , Simo Särkkä , Dominik Baumann

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

In an era of data abundance, statistical evidence is increasingly critical for business and policy decisions. Yet, organizations lack empirical tools to assess the value of evidence-based decision making (EBDM), optimize statistical…

In medical decision making, we have to choose among several expensive diagnostic tests such that the certainty about a patient's health is maximized while remaining within the bounds of resources like time and money. The expected increase…

人工智能 · 计算机科学 2019-09-19 Sarthak Ghosh , C. R. Ramakrishnan

We consider the problem of learning structures and parameters of Continuous-time Bayesian Networks (CTBNs) from time-course data under minimal experimental resources. In practice, the cost of generating experimental data poses a bottleneck,…

机器学习 · 统计学 2022-01-12 Dominik Linzner , Heinz Koeppl

The surrogate loss of variational autoencoders (VAEs) poses various challenges to their training, inducing the imbalance between task fitting and representation inference. To avert this, the existing strategies for VAEs focus on adjusting…

神经与进化计算 · 计算机科学 2024-04-02 Zhangkai Wu , Longbing Cao , Lei Qi

We introduce implicit Deep Adaptive Design (iDAD), a new method for performing adaptive experiments in real-time with implicit models. iDAD amortizes the cost of Bayesian optimal experimental design (BOED) by learning a design policy…

机器学习 · 统计学 2021-11-04 Desi R. Ivanova , Adam Foster , Steven Kleinegesse , Michael U. Gutmann , Tom Rainforth

Experimental design techniques such as active search and Bayesian optimization are widely used in the natural sciences for data collection and discovery. However, existing techniques tend to favor exploitation over exploration of the search…

机器学习 · 统计学 2024-05-07 Quan Nguyen , Adji Bousso Dieng

Deep generative models have been demonstrated as problematic in the unsupervised out-of-distribution (OOD) detection task, where they tend to assign higher likelihoods to OOD samples. Previous studies on this issue are usually not…

机器学习 · 计算机科学 2024-01-04 Zezhen Zeng , Bin Liu

Anomaly detection using dimensionality reduction has been an essential technique for monitoring multidimensional data. Although deep learning-based methods have been well studied for their remarkable detection performance, their…

机器学习 · 统计学 2018-12-24 Yasuhiro Ikeda , Kengo Tajiri , Yuusuke Nakano , Keishiro Watanabe , Keisuke Ishibashi

The European Medicines Agency has in recent years allowed licensing of new pharmaceuticals at an earlier stage in the clinical trial process. When trial evidence is obtained at an early stage, the events of interest, such as disease…

统计方法学 · 统计学 2021-03-26 Mathyn Vervaart , Mark Strong , Karl P. Claxton , Nicky J. Welton , Torbjørn Wisløff , Eline Aas

A key challenge in maximizing the benefits of Magnetic Resonance Imaging (MRI) in clinical settings is to accelerate acquisition times without significantly degrading image quality. This objective requires a balance between under-sampling…

机器学习 · 计算机科学 2025-06-23 Jacopo Iollo , Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

The variational autoencoder (VAE) is a popular, deep, latent-variable model (DLVM) due to its simple yet effective formulation for modeling the data distribution. Moreover, optimizing the VAE objective function is more manageable than other…

机器学习 · 计算机科学 2025-01-28 Surojit Saha , Sarang Joshi , Ross Whitaker

Obesity is a common issue in modern societies today that can lead to various diseases and significantly reduced quality of life. Currently, research has been conducted to investigate resting state EEG (electroencephalogram) signals with an…

机器学习 · 计算机科学 2023-02-03 Yuan Yue , Jeremiah D. Deng , Dirk De Ridder , Patrick Manning , Divya Adhia

In many machine learning tasks, input features with varying degrees of predictive capability are acquired at varying costs. In order to optimize the performance-cost trade-off, one would select features to observe a priori. However, given…

机器学习 · 计算机科学 2022-04-04 Randy Ardywibowo , Shahin Boluki , Zhangyang Wang , Bobak Mortazavi , Shuai Huang , Xiaoning Qian

We propose a general framework for sequential and dynamic acquisition of useful information in order to solve a particular task. While our goal could in principle be tackled by general reinforcement learning, our particular setting is…

机器学习 · 统计学 2016-02-09 He He , Paul Mineiro , Nikos Karampatziakis