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Cells and other soft particles are often forced to flow in confined geometries in both laboratory and natural environments, where the elastic deformation induces an additional drag and pressure drop across the particle. In contrast with…

流体动力学 · 物理学 2025-07-09 Charles Paul Moore , Hiba Belkadi , Brouna Safi , Gabriel Amselem , Charles N. Baroud

We explore the impact of geometrical corrugations on the near-wall flow properties of a soft-material driven in a confined rough microchannel. By means of numerical simulations, we perform a quantitative analysis of the relation between the…

软凝聚态物质 · 物理学 2020-06-22 F. Pelusi , M. Sbragaglia , A. Scagliarini , M. Lulli , M. Bernaschi , S. Succi

The lift and drag forces acting on a small, neutrally-buoyant spherical particle in a single-wall-bounded linear shear flow are examined via numerical computation. The effects of shear rate are isolated from those of slip by setting the…

We present a comparative modelling study of fluid-structure interactions in microchannels. Through a mathematical analysis based on plate theory and the lubrication approximation for low-Reynolds-number flow, we derive models for the flow…

流体动力学 · 物理学 2020-07-10 Tanmay C. Shidhore , Ivan C. Christov

Internal recirculation in a moving droplet plays an important role in several droplet-based microfluidic devices as it enhances mixing, chemical reaction and heat transfer. The occurrence of fluid slip at the wall, which becomes prominent…

流体动力学 · 物理学 2013-11-26 Joseph J Thalakkottor , Kamran Mohseni

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that…

软凝聚态物质 · 物理学 2023-01-18 Matthias Merkel , Lisa Manning

Through high-fidelity numerical simulation, the effect of the arrangement of micropillars on the flow characteristics and momentum transport has been extensively investigated. The surface friction due to the complex flow characteristics and…

流体动力学 · 物理学 2022-03-15 Yanxing Wang , Hui Wan , Tie Wei , Fangjun Shu

Direct Numerical Simulations of two superposed fluids in a channel with a textured surface on the lower wall have been carried out. A parametric study varying the viscosity ratio between the two fluids has been performed to mimic both {\bf…

流体动力学 · 物理学 2019-05-22 I. Arenas , E. Garcia , M. K. Fu , P. Orlandi , M. Hultmark , S. Leonardi

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

细胞行为 · 定量生物学 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

We have developed a coupled level set and volume of fluid-based computational fluid dynamics model to analyze the droplet formation mechanism in a square flow-focusing microchannel. We demonstrate a flexible manipulation of droplet…

流体动力学 · 物理学 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

Immiscible fluid displacement in porous media is fundamental for many environmental processes, including infiltration of water in soils, groundwater remediation, enhanced recovery of hydrocarbons and carbon geosequestration. Microstructural…

流体动力学 · 物理学 2019-05-22 Oshri Borgman , Thomas Darwent , Enrico Segre , Lucas Goehring , Ran Holtzman

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

生物物理 · 物理学 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing

The hygro-mechanical behavior of a hierarchical cellular material, i.e. growth rings of softwood is investigated using a two-scale micro-mechanics model based on a computational homogenization technique. The lower scale considers the…

材料科学 · 物理学 2015-09-22 Ahmad Rafsanjani , Dominique Derome , Falk K. Wittel , Jan Carmeliet

The guidance of human sperm cells under confinement in quasi 2D microchambers is investigated using a purely physical method to control their distribution. Transport property measurements and simulations are performed with dilute sperm…

In CFD simulations of two-phase flows, accurate drag force modeling is essential for predicting particle dynamics. However, a generally valid formulation is lacking, as all available drag force correlations have been established for…

流体动力学 · 物理学 2023-02-08 Gizem Ozler , Mustafa Demircioglu , Holger Grosshans

The persistent dynamics of active particles makes them explore extended portions of an obstacle's boundary during collisions. From impact to escape, the net applied forces depend on the curvature of the wall and increase in the presence of…

Active fluids generate internal active stress and exhibit unique responses to external forces such as superfluidity and self-yielding transitions. However, how confinement geometry influences these responses remains poorly understood. Here,…

Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces…

软凝聚态物质 · 物理学 2023-04-20 Siavash Monfared , Guruswami Ravichandran , Jose E. Andrade , Amin Doostmohammadi

Three dimensional simulations on the viscous folding in diverging microchannels reported by Cubaud and Mason are performed using the parallel code BLUE for multi-phase flows. The more viscous liquid L_1 is injected into the channel from the…

流体动力学 · 物理学 2016-09-14 Bingrui Xu , Jalel Chergui , Seungwon Shin , Damir Juric