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We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size,…

图像与视频处理 · 电气工程与系统科学 2020-01-01 Davood Karimi , Golnoosh Samei , Yanan Shao , Septimiu Salcudean

The current standard for detecting human epidermal growth factor receptor 2 (HER2) status in breast cancer patients relies on HER2 amplification, identified through fluorescence in situ hybridization (FISH) or immunohistochemistry (IHC).…

图像与视频处理 · 电气工程与系统科学 2024-09-27 Ardhendu Sekhar , Vrinda Goel , Garima Jain , Abhijeet Patil , Ravi Kant Gupta , Tripti Bameta , Swapnil Rane , Amit Sethi

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

图像与视频处理 · 电气工程与系统科学 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

图像与视频处理 · 电气工程与系统科学 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification in Whole-slide Lung Histopathology) challenge for evaluating…

Automated semantic segmentation of whole-slide images (WSIs) stained with hematoxylin and eosin (H&E) is essential for large-scale artificial intelligence-based biomarker analysis in breast cancer. However, existing public datasets for…

Goal: Squamous cell carcinoma of cervix is one of the most prevalent cancer worldwide in females. Traditionally, the most indispensable diagnosis of cervix squamous carcinoma is histopathological assessment which is achieved under…

计算机视觉与模式识别 · 计算机科学 2019-05-28 Ye Tian , Li Yang , Wei Wang , Jing Zhang , Qing Tang , Mili Ji , Yang Yu , Yu Li , Hong Yang , Airong Qian

The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

图像与视频处理 · 电气工程与系统科学 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Hematoxylin and Eosin (H&E) staining is a cornerstone of pathological analysis, offering reliable visualization of cellular morphology and tissue architecture for cancer diagnosis, subtyping, and grading. Immunohistochemistry (IHC) staining…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Amit Das , Naofumi Tomita , Kyle J. Syme , Weijie Ma , Paige O'Connor , Kristin N. Corbett , Bing Ren , Xiaoying Liu , Saeed Hassanpour

Pathologists diagnose and grade prostate cancer by examining tissue from needle biopsies on glass slides. The cancer's severity and risk of metastasis are determined by the Gleason grade, a score based on the organization and morphology of…

图像与视频处理 · 电气工程与系统科学 2022-09-28 Alessandro Ferrero , Beatrice Knudsen , Deepika Sirohi , Ross Whitaker

Accurate segmentation of the prostate is a key step in external beam radiation therapy treatments. In this paper, we tackle the challenging task of prostate segmentation in CT images by a two-stage network with 1) the first stage to fast…

图像与视频处理 · 电气工程与系统科学 2020-05-26 Kelei He , Chunfeng Lian , Bing Zhang , Xin Zhang , Xiaohuan Cao , Dong Nie , Yang Gao , Junfeng Zhang , Dinggang Shen

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

图像与视频处理 · 电气工程与系统科学 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to…

计算机视觉与模式识别 · 计算机科学 2020-05-26 Amartya Kalapahar , Julio Silva-Rodríguez , Adrián Colomer , Fernando López-Mir , Valery Naranjo

Inter-and intra-observer variation in delineating regions of interest (ROIs) occurs because of differences in expertise level and preferences of the radiation oncologists. We evaluated the accuracy of a segmentation model using the U-Net…

Purpose: Non-invasive grading of prostate cancer (PCa) from micro-ultrasound (micro-US) could expedite triage and guide biopsies toward the most aggressive regions, yet current models struggle to infer tissue micro-structure at coarse…

This paper addresses the problem of quantifying biomarkers in multi-stained tissues, based on color and spatial information. A deep learning based method that can automatically localize and quantify the cells expressing biomarker(s) in a…

组织与器官 · 定量生物学 2017-01-02 Fahime Sheikhzadeh , Martial Guillaud , Rabab K. Ward

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

图像与视频处理 · 电气工程与系统科学 2022-11-29 Heather D. Couture

Accurate segmentation of prostate and surrounding organs at risk is important for prostate cancer radiotherapy treatment planning. We present a fully automated workflow for male pelvic CT image segmentation using deep learning. The…