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Recent studies of cortical neurons driven by fluctuating currents revealed cutoff frequencies for action potential encoding of several hundred Hz. Theoretical studies of biophysical neuron models have predicted a much lower cutoff frequency…

神经元与认知 · 定量生物学 2015-05-27 Wei Wei , Fred Wolf

We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

生物物理 · 物理学 2007-05-23 S. Panzeri , S. R. Schultz

Probability density functions and the probability of Sz occurrence conditional upon the time elapsed from the previous Sz were estimated using the energy and intervals of SZ in prolonged recordings from subjects with localization- related…

神经元与认知 · 定量生物学 2008-02-04 Ivan Osorio , Mark G. Frei , Didier Sornette , John Milton

Electroencephalography (EEG) is an important clinical tool for grading injury caused by lack of oxygen or blood to the brain during birth. Characteristics of low-voltage waveforms, known as inter-bursts, are related to different grades of…

信号处理 · 电气工程与系统科学 2019-07-08 Sumit A. Raurale , Saif Nalband , Geraldine B. Boylan , Gordon Lightbody , John M. O'Toole

A good understanding of how neurons use electrical pulses (i.e, spikes) to encode the signal information remains elusive. Analyzing spike sequences generated by individual neurons and by two coupled neurons (using the stochastic…

神经元与认知 · 定量生物学 2019-10-23 Maria Masoliver , Cristina Masoller

Epileptic seizure prediction from electroencephalographic (EEG) recordings remains challenging due to strong inter-patient variability and the complex temporal structure of neural signals. This paper presents a patient-adaptive transformer…

机器学习 · 计算机科学 2026-03-31 Mohamed Mahdi , Asma Baghdadi

Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…

In drug-resistant epilepsy, presurgical evaluation of epilepsy can be considered. Magnetoencephalography (MEG) has been shown to be an effective exam to inform the localization of the epileptogenic zone through the localization of…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Pauline Mouches , Julien Jung , Armand Demasson , Agnès Guinard , Romain Bouet , Rosalie Marchal , Romain Quentin

Time irreversibility (temporal asymmetry) is one of fundamental properties that characterize the nonlinearity of complex dynamical processes, and our brain is a typical complex dynamical system manifested with nonlinearity. Two…

神经元与认知 · 定量生物学 2020-03-10 Yao Wen-po , Yao wen-li , Dai Jia-fei , Wang Jun

We present two Bayesian procedures to infer the interactions and external currents in an assembly of stochastic integrate-and-fire neurons from the recording of their spiking activity. The first procedure is based on the exact calculation…

机器学习 · 统计学 2011-02-28 Remi Monasson , Simona Cocco

Successful epilepsy surgery depends on localising and resecting cerebral abnormalities and networks that generate seizures. Abnormalities, however, may be widely distributed across multiple discontiguous areas. We propose spatially…

EEG-correlated fMRI analysis is widely used to detect regional blood oxygen level dependent fluctuations that are significantly synchronized to interictal epileptic discharges, which can provide evidence for localizing the ictal onset zone.…

信号处理 · 电气工程与系统科学 2020-05-04 Simon Van Eyndhoven , Patrick Dupont , Simon Tousseyn , Nico Vervliet , Wim Van Paesschen , Sabine Van Huffel , Borbála Hunyadi

Spike sorting refers to the problem of assigning action potentials observed in extra-cellular recordings of neural activity to the neuron(s) from which they originate. We cast this problem as one of learning a convolutional dictionary from…

统计方法学 · 统计学 2018-06-07 Andrew H. Song , Francisco Flores , Demba Ba

By computerized analysis of cortical activity recorded via fMRI for pediatric epilepsy patients, we implement algorithmic localization of epileptic seizure focus within one of eight cortical lobes. Our innovative machine learning techniques…

定量方法 · 定量生物学 2018-12-12 Rasoul Hekmati , Robert Azencott , Wei Zhang , Zili D. Chu , Michael J. Paldino

The ripple effect poses a significant challenge in knowledge editing for large language models. Namely, when a single fact is edited, the model struggles to accurately update the related facts in a sequence, which is evaluated by multi-hop…

计算与语言 · 计算机科学 2024-10-07 Zihao Zhao , Yuchen Yang , Yijiang Li , Yinzhi Cao

Continuously learning new classes without catastrophic forgetting is a challenging problem for on-device acoustic event classification given the restrictions on computation resources (e.g., model size, running memory). To alleviate such an…

音频与语音处理 · 电气工程与系统科学 2025-12-23 Yang Xiao

Intracranial EEG (IEEG) is used for 2 main purposes, to determine: (1) if epileptic networks are amenable to focal treatment and (2) where to intervene. Currently these questions are answered qualitatively and sometimes differently across…

In recent years, new technologies in neuroscience have made it possible to measure the activities of large numbers of neurons simultaneously in behaving animals. For each neuron, a fluorescence trace is measured; this can be seen as a…

应用统计 · 统计学 2017-11-15 Sean Jewell , Daniela Witten

In recent years, several studies have tended to show a respiratory drive in numerous brain areas so that the respiratory rhythm could be considered as a master clock promoting communication between distant brain areas. However, outside of…

神经元与认知 · 定量生物学 2022-09-02 Maxime Juventin , Mickael Zbili , Nicolas Fourcaud-Trocmé , Samuel Garcia , Nathalie Buonviso , Corine Amat

The electroencephalography (EEG), which is one of the easiest modes of recording brain activations in a non-invasive manner, is often distorted due to recording artifacts which adversely impacts the stimulus-response analysis. The most…

音频与语音处理 · 电气工程与系统科学 2021-11-30 Jaswanth Reddy Katthi , Sriram Ganapathy
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